MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
Epicatechin-3-gallate is a lipid of Polyketides (PK) class. Epicatechin-3-gallate is associated with abnormalities such as Epilepsy and Megalencephaly. The involved functions are known as Docking, Drug Interactions, inhibitors, Oxidation and Inflammation Process. Epicatechin-3-gallate often locates in Solitary microtubule component of centriole or axonemal complex, Palmar surface, Glial and peritoneal. The associated genes with Epicatechin-3-gallate are Homologous Gene and TSC1 gene.
To understand associated biological information of Epicatechin-3-gallate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Epicatechin-3-gallate is suspected in Epilepsy, Megalencephaly and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Epicatechin-3-gallate
MeSH term | MeSH ID | Detail |
---|---|---|
Colonic Neoplasms | D003110 | 161 associated lipids |
Cicatrix | D002921 | 9 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Vaidyanathan JB and Walle T | Cellular uptake and efflux of the tea flavonoid (-)epicatechin-3-gallate in the human intestinal cell line Caco-2. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12970388 |
Kadowaki M et al. | Presence or absence of a gallate moiety on catechins affects their cellular transport. | 2008 | J. Pharm. Pharmacol. | pmid:18718123 |
Yokozawa T et al. | (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. | 2004 | J. Pharm. Pharmacol. | pmid:15005882 |
Nakamura H et al. | Green tea catechin inhibits lipopolysaccharide-induced bone resorption in vivo. | 2010 | J. Periodont. Res. | pmid:19602116 |
Hayes CJ et al. | Synthesis and preliminary anticancer activity studies of C4 and C8-modified derivatives of catechin gallate (CG) and epicatechin gallate (ECG). | 2006 | J. Org. Chem. | pmid:17168588 |
Kobayashi K et al. | Strong Inhibition of Secretory Sphingomyelinase by Catechins, Particularly by (-)-Epicatechin 3-O-Gallate and (-)-3'-O-Methylepigallocatechin 3-O-Gallate. | 2016 | J. Nutr. Sci. Vitaminol. | pmid:27264097 |
Minoda K et al. | Influence of the galloyl moiety in tea catechins on binding affinity for human serum albumin. | 2010 | J. Nutr. Sci. Vitaminol. | pmid:21228505 |
Manna S et al. | Tea polyphenols can restrict benzo[a]pyrene-induced lung carcinogenesis by altered expression of p53-associated genes and H-ras, c-myc and cyclin D1. | 2009 | J. Nutr. Biochem. | pmid:18656336 |
Hosokawa Y et al. | Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts. | 2010 | J. Nutr. Biochem. | pmid:19616927 |
Zhu W et al. | A-type ECG and EGCG dimers disturb the structure of 3T3-L1 cell membrane and strongly inhibit its differentiation by targeting peroxisome proliferator-activated receptor γ with miR-27 involved mechanism. | 2015 | J. Nutr. Biochem. | pmid:26145192 |