MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Procyanidin B2 is a lipid of Polyketides (PK) class. The involved functions are known as conjugation, Methylation, Excretory function, enzyme activity and sulfatase activity. Procyanidin b2 often locates in Blood, Epidermis and Upper Gastrointestinal Tract. The associated genes with Procyanidin B2 are NR5A2 gene, HRAS wt Allele, CFB gene, PTGS2 gene and MAPK8 gene.
To understand associated biological information of Procyanidin B2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Procyanidin B2
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
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Appeldoorn MM et al. | Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats. | 2009 | J. Nutr. | pmid:19494022 |
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Qa'dan F et al. | Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo. | 2009 | J Ethnopharmacol | pmid:19397981 |
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Stoupi S et al. | In vivo bioavailability, absorption, excretion, and pharmacokinetics of [14C]procyanidin B2 in male rats. | 2010 | Drug Metab. Dispos. | pmid:19910517 |
Stoupi S et al. | Procyanidin B2 catabolism by human fecal microflora: partial characterization of 'dimeric' intermediates. | 2010 | Arch. Biochem. Biophys. | pmid:20188693 |
Stoupi S et al. | A comparison of the in vitro biotransformation of (-)-epicatechin and procyanidin B2 by human faecal microbiota. | 2010 | Mol Nutr Food Res | pmid:19943260 |
Chou SC et al. | Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells. | 2010 | Pharm. Res. | pmid:20162340 |
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Li BY et al. | Induction of lactadherin mediates the apoptosis of endothelial cells in response to advanced glycation end products and protective effects of grape seed procyanidin B2 and resveratrol. | 2011 | Apoptosis | pmid:21505870 |
Li BY et al. | Grape seed procyanidin B2 inhibits advanced glycation end product-induced endothelial cell apoptosis through regulating GSK3β phosphorylation. | 2011 | Cell Biol. Int. | pmid:21244366 |
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Shrestha SP et al. | Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver. | 2012 | Pharm. Res. | pmid:22068277 |
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Zhang Z et al. | Proteomic analysis of kidney and protective effects of grape seed procyanidin B2 in db/db mice indicate MFG-E8 as a key molecule in the development of diabetic nephropathy. | 2013 | Biochim. Biophys. Acta | pmid:23474305 |
Li XL et al. | PIMT prevents the apoptosis of endothelial cells in response to glycated low density lipoproteins and protective effects of grape seed procyanidin B2. | 2013 | PLoS ONE | pmid:23922881 |
Fukami H et al. | Isolation of a reduced form of cyanidin 3-O-β-D-glucoside from immature black soybean (Glycine max (L.) Merr.) and its reducing properties. | 2013 | J Oleo Sci | pmid:23985492 |
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Muthenna P et al. | Inhibition of protein glycation by procyanidin-B2 enriched fraction of cinnamon: delay of diabetic cataract in rats. | 2013 | IUBMB Life | pmid:24136906 |
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Sung NY et al. | Procyanidin dimer B2-mediated IRAK-M induction negatively regulates TLR4 signaling in macrophages. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23872113 |
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Yang H et al. | Procyanidin B2 inhibits NLRP3 inflammasome activation in human vascular endothelial cells. | 2014 | Biochem. Pharmacol. | pmid:25450671 |
Jeong JH et al. | An investigation into the ameliorating effect of black soybean extract on learning and memory impairment with assessment of neuroprotective effects. | 2014 | BMC Complement Altern Med | pmid:25496367 |
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Zuriarrain A et al. | Polyphenolic profile in cider and antioxidant power. | 2015 | J. Sci. Food Agric. | pmid:25475490 |
Yang BY et al. | Protective Effect of Procyanidin B2 against CCl4-Induced Acute Liver Injury in Mice. | 2015 | Molecules | pmid:26151119 |
Kopustinskiene DM et al. | Direct effects of (-)-epicatechin and procyanidin B2 on the respiration of rat heart mitochondria. | 2015 | Biomed Res Int | pmid:25811024 |
Bao L et al. | Grape seed procyanidin B2 ameliorates mitochondrial dysfunction and inhibits apoptosis via the AMP-activated protein kinase-silent mating type information regulation 2 homologue 1-PPARγ co-activator-1α axis in rat mesangial cells under high-dose glucosamine. | 2015 | Br. J. Nutr. | pmid:25404010 |
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Martinez-Micaelo N et al. | Procyanidin B2 inhibits inflammasome-mediated IL-1β production in lipopolysaccharide-stimulated macrophages. | 2015 | Mol Nutr Food Res | pmid:25379992 |
Yin W et al. | Critical role of prohibitin in endothelial cell apoptosis caused by glycated low-density lipoproteins and protective effects of grape seed procyanidin B2. | 2015 | J. Cardiovasc. Pharmacol. | pmid:25343566 |