| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
Total
4
Procyanidin B2
Procyanidin B2 is a lipid of Polyketides (PK) class. The involved functions are known as conjugation, Methylation, Excretory function, enzyme activity and sulfatase activity. Procyanidin b2 often locates in Blood, Epidermis and Upper Gastrointestinal Tract. The associated genes with Procyanidin B2 are NR5A2 gene, HRAS wt Allele, CFB gene, PTGS2 gene and MAPK8 gene.
Cross Reference
Introduction
To understand associated biological information of Procyanidin B2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Procyanidin B2?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Procyanidin B2
PubChem Associated disorders and diseases
What pathways are associated with Procyanidin B2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Procyanidin B2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Procyanidin B2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Procyanidin B2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Procyanidin B2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Procyanidin B2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Procyanidin B2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xiao Y et al. | Procyanidin B2 protects against d-galactose-induced mimetic aging in mice: Metabolites and microbiome analysis. | 2018 | Food Chem. Toxicol. | pmid:29751077 |
| Fayeulle N et al. | Characterization of new flavan-3-ol derivatives in fermented cocoa beans. | 2018 | Food Chem | pmid:29680045 |
| Vallejo-Ochoa J et al. | Early plant growth and biochemical responses induced by Azospirillum brasilense Sp245 lipopolysaccharides in wheat (Triticum aestivum L.) seedlings are attenuated by procyanidin B2. | 2018 | Protoplasma | pmid:29110138 |
| Deng M et al. | Effect of Storage Conditions on Phenolic Profiles and Antioxidant Activity of Litchi Pericarp. | 2018 | Molecules | pmid:30200581 |
| Shi Q et al. | Comparative Analysis of Pigments, Phenolics, and Antioxidant Activity of Chinese Jujube ( Mill.) during Fruit Development. | 2018 | Molecules | pmid:30071615 |
| Saenger T et al. | Short-term biomarkers of apple consumption. | 2017 | Mol Nutr Food Res | pmid:27794196 |
| Wang W et al. | Procyanidin B2 ameliorates carrageenan-induced chronic nonbacterial prostatitis in rats via anti-inflammatory and activation of the Nrf2 pathway. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28844677 |
| Matić P et al. | Validation of Spectrophotometric Methods for the Determination of Total Polyphenol and Total Flavonoid Content. | 2017 | J AOAC Int | pmid:28730980 |
| Yin M et al. | Grape seed procyanidin B2 ameliorates hepatic lipid metabolism disorders in db/db mice. | 2017 | Mol Med Rep | pmid:28677803 |
| Chen Y et al. | Anti-myocardial Ischemia Effect and Components of Litchi Pericarp Extracts. | 2017 | Phytother Res | pmid:28744920 |
| Kim AN et al. | The effect of grinding at various vacuum levels on the color, phenolics, and antioxidant properties of apple. | 2017 | Food Chem | pmid:27596414 |
| Novakovic A et al. | Endothelium-dependent vasorelaxant effect of procyanidin B2 on human internal mammary artery. | 2017 | Eur. J. Pharmacol. | pmid:28414054 |
| Tanaka S et al. | Procyanidin B2 gallates inhibit IFN-γ and IL-17 production in T cells by suppressing T-bet and RORγt expression. | 2017 | Int. Immunopharmacol. | pmid:28088699 |
| Sereia AL et al. | Capillary Electrophoresis as Tool for Diastereomeric Separation in a Trichilia catigua Fraction. | 2017 | Phytochem Anal | pmid:27910216 |
| Escott C et al. | Characterization of polymeric pigments and pyranoanthocyanins formed in microfermentations of non-Saccharomyces yeasts. | 2016 | J. Appl. Microbiol. | pmid:27511798 |
| Cuadrado-Silva CT et al. | Targeted Metabolomic Analysis of Polyphenols with Antioxidant Activity in Sour Guava (Psidium friedrichsthalianum Nied.) Fruit. | 2016 | Molecules | pmid:28025550 |
| Zhang JQ et al. | Critical Role of FoxO1 in Granulosa Cell Apoptosis Caused by Oxidative Stress and Protective Effects of Grape Seed Procyanidin B2. | 2016 | Oxid Med Cell Longev | pmid:27057282 |
| Wang A et al. | Procyanidins Mitigate Osteoarthritis Pathogenesis by, at Least in Part, Suppressing Vascular Endothelial Growth Factor Signaling. | 2016 | Int J Mol Sci | pmid:27941690 |
| Cherubin P et al. | Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds. | 2016 | PLoS ONE | pmid:27829022 |
| Zhou Y et al. | Restoration of Mimecan Expression by Grape Seed Procyanidin B2 Through Regulation of Nuclear Factor-kappaB in Mice With Diabetic Nephropathy. | 2016 | Iran J Kidney Dis | pmid:27721232 |
| Cai X et al. | Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro. | 2016 | Food Funct | pmid:26650960 |
| Li W et al. | Supplementation of procyanidins B2 attenuates photooxidation-induced apoptosis in ARPE-19 cells. | 2016 | Int J Food Sci Nutr | pmid:27251367 |
| Tessarin P et al. | Influence of canopy-applied chitosan on the composition of organic cv. Sangiovese and Cabernet Sauvignon berries and wines. | 2016 | Food Chem | pmid:27211677 |
| Lima Mdos S et al. | Phenolic compounds, organic acids and antioxidant activity of grape juices produced in industrial scale by different processes of maceration. | 2015 | Food Chem | pmid:26041208 |
| Liszt KI et al. | Identification of Catechin, Syringic Acid, and Procyanidin B2 in Wine as Stimulants of Gastric Acid Secretion. | 2015 | J. Agric. Food Chem. | pmid:26244870 |
| Wu S et al. | Procyanidin B2 attenuates neurological deficits and blood-brain barrier disruption in a rat model of cerebral ischemia. | 2015 | Mol Nutr Food Res | pmid:26228251 |
| Yin W et al. | Anti-inflammatory effects of grape seed procyanidin B2 on a diabetic pancreas. | 2015 | Food Funct | pmid:26207855 |
| Schmuch J et al. | Extract from Rumex acetosa L. for prophylaxis of periodontitis: inhibition of bacterial in vitro adhesion and of gingipains of Porphyromonas gingivalis by epicatechin-3-O-(4β→8)-epicatechin-3-O-gallate (procyanidin-B2-Di-gallate). | 2015 | PLoS ONE | pmid:25803708 |
| Zuriarrain A et al. | Polyphenolic profile in cider and antioxidant power. | 2015 | J. Sci. Food Agric. | pmid:25475490 |
| Yang BY et al. | Protective Effect of Procyanidin B2 against CCl4-Induced Acute Liver Injury in Mice. | 2015 | Molecules | pmid:26151119 |
| Kopustinskiene DM et al. | Direct effects of (-)-epicatechin and procyanidin B2 on the respiration of rat heart mitochondria. | 2015 | Biomed Res Int | pmid:25811024 |
| Bao L et al. | Grape seed procyanidin B2 ameliorates mitochondrial dysfunction and inhibits apoptosis via the AMP-activated protein kinase-silent mating type information regulation 2 homologue 1-PPARγ co-activator-1α axis in rat mesangial cells under high-dose glucosamine. | 2015 | Br. J. Nutr. | pmid:25404010 |
| Jiang X et al. | Analysis of accumulation patterns and preliminary study on the condensation mechanism of proanthocyanidins in the tea plant [Camellia sinensis]. | 2015 | Sci Rep | pmid:25735226 |
| Wen L et al. | Phenolic contents and cellular antioxidant activity of Chinese hawthorn "Crataegus pinnatifida". | 2015 | Food Chem | pmid:25976791 |
| Martinez-Micaelo N et al. | Procyanidin B2 inhibits inflammasome-mediated IL-1β production in lipopolysaccharide-stimulated macrophages. | 2015 | Mol Nutr Food Res | pmid:25379992 |
| Yin W et al. | Critical role of prohibitin in endothelial cell apoptosis caused by glycated low-density lipoproteins and protective effects of grape seed procyanidin B2. | 2015 | J. Cardiovasc. Pharmacol. | pmid:25343566 |
| Li D et al. | Procyanidin B2 inhibits high glucose‑induced epithelial‑mesenchymal transition in HK‑2 human renal proximal tubular epithelial cells. | 2015 | Mol Med Rep | pmid:26498003 |
| Shilpi A et al. | Mechanisms of DNA methyltransferase-inhibitor interactions: Procyanidin B2 shows new promise for therapeutic intervention of cancer. | 2015 | Chem. Biol. Interact. | pmid:25839702 |
| Luan SS et al. | Quantitative proteomics study of protective effects of grape seed procyanidin B2 on diabetic cardiomyopathy in db/db mice. | 2014 | Biosci. Biotechnol. Biochem. | pmid:25209507 |
| Muthenna P et al. | Effect of cinnamon and its procyanidin-B2 enriched fraction on diabetic nephropathy in rats. | 2014 | Chem. Biol. Interact. | pmid:25199697 |
| De Taeye C et al. | Degradation of (-)-epicatechin and procyanidin B2 in aqueous and lipidic model systems. first evidence of "chemical" flavan-3-ol oligomers in processed cocoa. | 2014 | J. Agric. Food Chem. | pmid:25167469 |
| Espley RV et al. | Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice. | 2014 | J. Nutr. | pmid:24353343 |
| Gaivelyte K et al. | Variation of quantitative composition of phenolic compounds in rowan (Sorbus aucuparia L.) leaves during the growth season. | 2014 | Nat. Prod. Res. | pmid:24697599 |
| Baselga-Escudero L et al. | Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells. | 2014 | Nucleic Acids Res. | pmid:24165878 |
| Ou K et al. | Microbial catabolism of procyanidins by human gut microbiota. | 2014 | Mol Nutr Food Res | pmid:25045165 |
| Ekuadzi E et al. | Chemical constituents from Gouania longipetala and Glyphaea brevis. | 2014 | Nat. Prod. Res. | pmid:24910899 |
| Yang H et al. | Procyanidin B2 inhibits NLRP3 inflammasome activation in human vascular endothelial cells. | 2014 | Biochem. Pharmacol. | pmid:25450671 |
| Jeong JH et al. | An investigation into the ameliorating effect of black soybean extract on learning and memory impairment with assessment of neuroprotective effects. | 2014 | BMC Complement Altern Med | pmid:25496367 |
| Bai X et al. | Antioxidant activity and HPLC analysis of polyphenol-enriched extracts from industrial apple pomace. | 2013 | J. Sci. Food Agric. | pmid:23460126 |
| Zhang Z et al. | Proteomic analysis of kidney and protective effects of grape seed procyanidin B2 in db/db mice indicate MFG-E8 as a key molecule in the development of diabetic nephropathy. | 2013 | Biochim. Biophys. Acta | pmid:23474305 |