MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Procyanidin B2 is a lipid of Polyketides (PK) class. The involved functions are known as conjugation, Methylation, Excretory function, enzyme activity and sulfatase activity. Procyanidin b2 often locates in Blood, Epidermis and Upper Gastrointestinal Tract. The associated genes with Procyanidin B2 are NR5A2 gene, HRAS wt Allele, CFB gene, PTGS2 gene and MAPK8 gene.
To understand associated biological information of Procyanidin B2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Procyanidin B2
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cho ES et al. | Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK. | 2008 | Mutat. Res. | pmid:18272186 |
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Tanaka K et al. | Evaluation of the quality of Chinese and Vietnamese cassia using LC-MS and multivariate analysis. | 2013 | Nat Prod Commun | pmid:23472464 |
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Baselga-Escudero L et al. | Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells. | 2014 | Nucleic Acids Res. | pmid:24165878 |
Nomoto H et al. | Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis. | 2004 | Nutr Cancer | pmid:15456639 |
Waffo-Téguo P et al. | Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. | 2001 | Nutr Cancer | pmid:11962253 |
Zhang JQ et al. | Critical Role of FoxO1 in Granulosa Cell Apoptosis Caused by Oxidative Stress and Protective Effects of Grape Seed Procyanidin B2. | 2016 | Oxid Med Cell Longev | pmid:27057282 |
Chou SC et al. | Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells. | 2010 | Pharm. Res. | pmid:20162340 |
Shrestha SP et al. | Glucuronidation and methylation of procyanidin dimers b2 and 3,3″-di-o-galloyl-b2 and corresponding monomers epicatechin and 3-o-galloyl-epicatechin in mouse liver. | 2012 | Pharm. Res. | pmid:22068277 |
Butterweck V et al. | Pharmacological and endocrine effects of Hypericum perforatum and hypericin after repeated treatment. | 2001 | Pharmacopsychiatry | pmid:11518068 |
Quettier-Deleu C et al. | Hawthorn extracts inhibit LDL oxidation. | 2003 | Pharmazie | pmid:12967038 |
Sereia AL et al. | Capillary Electrophoresis as Tool for Diastereomeric Separation in a Trichilia catigua Fraction. | 2017 | Phytochem Anal | pmid:27910216 |
Alvarez AL et al. | Bioactivity-guided fractionation of Phyllanthus orbicularis and identification of the principal anti HSV-2 compounds. | 2012 | Phytother Res | pmid:22318977 |
Chen Y et al. | Anti-myocardial Ischemia Effect and Components of Litchi Pericarp Extracts. | 2017 | Phytother Res | pmid:28744920 |
Hussein G et al. | Inhibitory effects of Sudanese plant extracts on HIV-1 replication and HIV-1 protease. | 1999 | Phytother Res | pmid:10189947 |
Abrahams S et al. | Identification and biochemical characterization of mutants in the proanthocyanidin pathway in Arabidopsis. | 2002 | Plant Physiol. | pmid:12376625 |
Shahat AA et al. | Antiviral and antioxidant activity of flavonoids and proanthocyanidins from Crataegus sinaica. | 2002 | Planta Med. | pmid:12094299 |
Butterweck V et al. | Plasma levels of hypericin in presence of procyanidin B2 and hyperoside: a pharmacokinetic study in rats. | 2003 | Planta Med. | pmid:12677519 |
Yu F et al. | Proteomic analysis of aorta and protective effects of grape seed procyanidin B2 in db/db mice reveal a critical role of milk fat globule epidermal growth factor-8 in diabetic arterial damage. | 2012 | PLoS ONE | pmid:23285083 |
Li XL et al. | PIMT prevents the apoptosis of endothelial cells in response to glycated low density lipoproteins and protective effects of grape seed procyanidin B2. | 2013 | PLoS ONE | pmid:23922881 |
Schmuch J et al. | Extract from Rumex acetosa L. for prophylaxis of periodontitis: inhibition of bacterial in vitro adhesion and of gingipains of Porphyromonas gingivalis by epicatechin-3-O-(4β→8)-epicatechin-3-O-gallate (procyanidin-B2-Di-gallate). | 2015 | PLoS ONE | pmid:25803708 |
Cherubin P et al. | Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds. | 2016 | PLoS ONE | pmid:27829022 |
Vallejo-Ochoa J et al. | Early plant growth and biochemical responses induced by Azospirillum brasilense Sp245 lipopolysaccharides in wheat (Triticum aestivum L.) seedlings are attenuated by procyanidin B2. | 2018 | Protoplasma | pmid:29110138 |
Jiang X et al. | Analysis of accumulation patterns and preliminary study on the condensation mechanism of proanthocyanidins in the tea plant [Camellia sinensis]. | 2015 | Sci Rep | pmid:25735226 |
Kamimura A et al. | Procyanidin oligomers counteract TGF-beta1- and TGF-beta2-induced apoptosis in hair epithelial cells: an insight into their mechanisms. | 2006 | Skin Pharmacol Physiol | pmid:16778458 |
Ramos S et al. | Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells. | 2011 | Toxicol In Vitro | pmid:21945981 |
Zhou DN et al. | [Phenols from the rhizomes of Arachniodes exilis]. | 2008 | Zhong Yao Cai | pmid:18619264 |
Huang XZ et al. | [Studies on chemical constituents from roots of Craibiodendron henryi]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17583200 |