MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Procyanidin B2 is a lipid of Polyketides (PK) class. The involved functions are known as conjugation, Methylation, Excretory function, enzyme activity and sulfatase activity. Procyanidin b2 often locates in Blood, Epidermis and Upper Gastrointestinal Tract. The associated genes with Procyanidin B2 are NR5A2 gene, HRAS wt Allele, CFB gene, PTGS2 gene and MAPK8 gene.
To understand associated biological information of Procyanidin B2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Procyanidin B2
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nomoto H et al. | Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis. | 2004 | Nutr Cancer | pmid:15456639 |
Sakano K et al. | Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. | 2005 | Free Radic. Biol. Med. | pmid:16198231 |
Saito A et al. | Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases. | 2005 | Bioorg. Med. Chem. | pmid:15781387 |
Contreras-DomÃnguez M et al. | Degradation of procyanidins by Aspergillus fumigatus: identification of a novel aromatic ring cleavage product. | 2006 | Biochimie | pmid:16905239 |
Chen DM et al. | Inhibitory effects of procyanidin B(2) dimer on lipid-laden macrophage formation. | 2006 | J. Cardiovasc. Pharmacol. | pmid:16954822 |
Kamimura A et al. | Procyanidin oligomers counteract TGF-beta1- and TGF-beta2-induced apoptosis in hair epithelial cells: an insight into their mechanisms. | 2006 | Skin Pharmacol Physiol | pmid:16778458 |
Zhang WY et al. | Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] suppresses the expression of cyclooxygenase-2 in endotoxin-treated monocytic cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16681998 |
Jo JY et al. | Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols. | 2006 | J. Agric. Food Chem. | pmid:16536579 |
Huang XZ et al. | [Studies on chemical constituents from roots of Craibiodendron henryi]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17583200 |
Lee KW et al. | Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities. | 2008 | Cardiovasc. Res. | pmid:18310679 |