MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Procyanidin B2 is a lipid of Polyketides (PK) class. The involved functions are known as conjugation, Methylation, Excretory function, enzyme activity and sulfatase activity. Procyanidin b2 often locates in Blood, Epidermis and Upper Gastrointestinal Tract. The associated genes with Procyanidin B2 are NR5A2 gene, HRAS wt Allele, CFB gene, PTGS2 gene and MAPK8 gene.
To understand associated biological information of Procyanidin B2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Procyanidin B2
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Martinez-Micaelo N et al. | Omega-3 docosahexaenoic acid and procyanidins inhibit cyclo-oxygenase activity and attenuate NF-κB activation through a p105/p50 regulatory mechanism in macrophage inflammation. | 2012 | Biochem. J. | pmid:21954853 |
Feliciano RP et al. | Comparison of isolated cranberry (Vaccinium macrocarpon Ait.) proanthocyanidins to catechin and procyanidins A2 and B2 for use as standards in the 4-(dimethylamino)cinnamaldehyde assay. | 2012 | J. Agric. Food Chem. | pmid:22533362 |
Zumdick S et al. | In vitro intestinal transport of oligomeric procyanidins (DP 2 to 4) across monolayers of Caco-2 cells. | 2012 | Fitoterapia | pmid:22776719 |
Ottaviani JI et al. | Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans. | 2012 | Am. J. Clin. Nutr. | pmid:22378733 |
Yu F et al. | Proteomic analysis of aorta and protective effects of grape seed procyanidin B2 in db/db mice reveal a critical role of milk fat globule epidermal growth factor-8 in diabetic arterial damage. | 2012 | PLoS ONE | pmid:23285083 |
Crupi P et al. | HPLC-DAD-ESI-MS analysis of flavonoid compounds in 5 seedless table grapes grown in Apulian Region. | 2012 | J. Food Sci. | pmid:22309436 |
RodrÃguez-Ramiro I et al. | Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway. | 2011 | J. Nutr. Biochem. | pmid:21334869 |
Li BY et al. | Induction of lactadherin mediates the apoptosis of endothelial cells in response to advanced glycation end products and protective effects of grape seed procyanidin B2 and resveratrol. | 2011 | Apoptosis | pmid:21505870 |
Li BY et al. | Grape seed procyanidin B2 inhibits advanced glycation end product-induced endothelial cell apoptosis through regulating GSK3β phosphorylation. | 2011 | Cell Biol. Int. | pmid:21244366 |
Kahle K et al. | Intestinal transit and systemic metabolism of apple polyphenols. | 2011 | Eur J Nutr | pmid:21184087 |
Poupard P et al. | Characterization of procyanidin B2 oxidation products in an apple juice model solution and confirmation of their presence in apple juice by high-performance liquid chromatography coupled to electrospray ion trap mass spectrometry. | 2011 | J Mass Spectrom | pmid:22124992 |
Cai Q et al. | Grape seed procyanidin b2 inhibits human aortic smooth muscle cell proliferation and migration induced by advanced glycation end products. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21897042 |
Ramos S et al. | Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells. | 2011 | Toxicol In Vitro | pmid:21945981 |
RodrÃguez-Ramiro I et al. | Comparative effects of dietary flavanols on antioxidant defences and their response to oxidant-induced stress on Caco2 cells. | 2011 | Eur J Nutr | pmid:21046126 |
Gescher K et al. | Oligomeric proanthocyanidins from Rumex acetosa L. inhibit the attachment of herpes simplex virus type-1. | 2011 | Antiviral Res. | pmid:21070811 |
Stoupi S et al. | In vivo bioavailability, absorption, excretion, and pharmacokinetics of [14C]procyanidin B2 in male rats. | 2010 | Drug Metab. Dispos. | pmid:19910517 |
Stoupi S et al. | Procyanidin B2 catabolism by human fecal microflora: partial characterization of 'dimeric' intermediates. | 2010 | Arch. Biochem. Biophys. | pmid:20188693 |
Stoupi S et al. | A comparison of the in vitro biotransformation of (-)-epicatechin and procyanidin B2 by human faecal microbiota. | 2010 | Mol Nutr Food Res | pmid:19943260 |
Chou SC et al. | Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells. | 2010 | Pharm. Res. | pmid:20162340 |
Appeldoorn MM et al. | Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats. | 2009 | J. Nutr. | pmid:19494022 |