Procyanidin B2

Procyanidin B2 is a lipid of Polyketides (PK) class. The involved functions are known as conjugation, Methylation, Excretory function, enzyme activity and sulfatase activity. Procyanidin b2 often locates in Blood, Epidermis and Upper Gastrointestinal Tract. The associated genes with Procyanidin B2 are NR5A2 gene, HRAS wt Allele, CFB gene, PTGS2 gene and MAPK8 gene.

Cross Reference

Introduction

To understand associated biological information of Procyanidin B2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Procyanidin B2?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Procyanidin B2

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with Procyanidin B2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Procyanidin B2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Procyanidin B2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Procyanidin B2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Procyanidin B2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Procyanidin B2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Procyanidin B2

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Authors Title Published Journal PubMed Link
Yin M et al. Grape seed procyanidin B2 ameliorates hepatic lipid metabolism disorders in db/db mice. 2017 Mol Med Rep pmid:28677803
Li D et al. Procyanidin B2 inhibits high glucose‑induced epithelial‑mesenchymal transition in HK‑2 human renal proximal tubular epithelial cells. 2015 Mol Med Rep pmid:26498003
Bai X et al. Antioxidant activity and HPLC analysis of polyphenol-enriched extracts from industrial apple pomace. 2013 J. Sci. Food Agric. pmid:23460126
Zuriarrain A et al. Polyphenolic profile in cider and antioxidant power. 2015 J. Sci. Food Agric. pmid:25475490
Kozikowski AP et al. Studies in polyphenol chemistry and bioactivity. 2. Establishment of interflavan linkage regio- and stereochemistry by oxidative degradation of an O-alkylated derivative of procyanidin B2 to (R)-(-)-2,4-diphenylbutyric acid. 2000 J. Org. Chem. pmid:10993368
Rodríguez-Ramiro I et al. Procyanidin B2 and a cocoa polyphenolic extract inhibit acrylamide-induced apoptosis in human Caco-2 cells by preventing oxidative stress and activation of JNK pathway. 2011 J. Nutr. Biochem. pmid:21334869
Appeldoorn MM et al. Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats. 2009 J. Nutr. pmid:19494022
Espley RV et al. Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice. 2014 J. Nutr. pmid:24353343
Foo LY et al. A-Type proanthocyanidin trimers from cranberry that inhibit adherence of uropathogenic P-fimbriated Escherichia coli. 2000 J. Nat. Prod. pmid:11000024
De Bruyne T et al. Biological evaluation of proanthocyanidin dimers and related polyphenols. 1999 J. Nat. Prod. pmid:10425115