MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Procyanidin B2 is a lipid of Polyketides (PK) class. The involved functions are known as conjugation, Methylation, Excretory function, enzyme activity and sulfatase activity. Procyanidin b2 often locates in Blood, Epidermis and Upper Gastrointestinal Tract. The associated genes with Procyanidin B2 are NR5A2 gene, HRAS wt Allele, CFB gene, PTGS2 gene and MAPK8 gene.
To understand associated biological information of Procyanidin B2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Procyanidin B2
MeSH term | MeSH ID | Detail |
---|---|---|
Diabetes Mellitus | D003920 | 90 associated lipids |
Diabetic Nephropathies | D003928 | 39 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cho ES et al. | Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activity. | 2009 | Free Radic. Biol. Med. | pmid:19248828 |
Appeldoorn MM et al. | Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats. | 2009 | J. Nutr. | pmid:19494022 |
Takeshita M et al. | Proanthocyanidin from blueberry leaves suppresses expression of subgenomic hepatitis C virus RNA. | 2009 | J. Biol. Chem. | pmid:19531480 |
Qa'dan F et al. | Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo. | 2009 | J Ethnopharmacol | pmid:19397981 |
Lee KW et al. | Cocoa procyanidins inhibit expression and activation of MMP-2 in vascular smooth muscle cells by direct inhibition of MEK and MT1-MMP activities. | 2008 | Cardiovasc. Res. | pmid:18310679 |
Xiao JS et al. | Rapid preparation of procyanidins B2 and C1 from Granny Smith apples by using low pressure column chromatography and identification of their oligomeric procyanidins. | 2008 | J. Agric. Food Chem. | pmid:18298060 |
Cho ES et al. | Cocoa procyanidins protect PC12 cells from hydrogen-peroxide-induced apoptosis by inhibiting activation of p38 MAPK and JNK. | 2008 | Mutat. Res. | pmid:18272186 |
Mackenzie GG et al. | Dimeric procyanidin B2 inhibits constitutively active NF-kappaB in Hodgkin's lymphoma cells independently of the presence of IkappaB mutations. | 2008 | Biochem. Pharmacol. | pmid:18275936 |
Kang NJ et al. | Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase. | 2008 | J. Biol. Chem. | pmid:18519570 |
Zhou DN et al. | [Phenols from the rhizomes of Arachniodes exilis]. | 2008 | Zhong Yao Cai | pmid:18619264 |
Hosoi S et al. | Analysis of CYP3A inhibitory components of star fruit (Averrhoa carambola L.) using liquid chromatography-mass spectrometry. | 2008 | J Nat Med | pmid:18404300 |
Huang XZ et al. | [Studies on chemical constituents from roots of Craibiodendron henryi]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17583200 |
Contreras-DomÃnguez M et al. | Degradation of procyanidins by Aspergillus fumigatus: identification of a novel aromatic ring cleavage product. | 2006 | Biochimie | pmid:16905239 |
Chen DM et al. | Inhibitory effects of procyanidin B(2) dimer on lipid-laden macrophage formation. | 2006 | J. Cardiovasc. Pharmacol. | pmid:16954822 |
Kamimura A et al. | Procyanidin oligomers counteract TGF-beta1- and TGF-beta2-induced apoptosis in hair epithelial cells: an insight into their mechanisms. | 2006 | Skin Pharmacol Physiol | pmid:16778458 |
Zhang WY et al. | Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] suppresses the expression of cyclooxygenase-2 in endotoxin-treated monocytic cells. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16681998 |
Jo JY et al. | Catalytic inhibition of human DNA topoisomerase II by interactions of grape cell culture polyphenols. | 2006 | J. Agric. Food Chem. | pmid:16536579 |
Sakano K et al. | Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. | 2005 | Free Radic. Biol. Med. | pmid:16198231 |
Saito A et al. | Systematic synthesis of galloyl-substituted procyanidin B1 and B2, and their ability of DPPH radical scavenging activity and inhibitory activity of DNA polymerases. | 2005 | Bioorg. Med. Chem. | pmid:15781387 |
Chinnici F et al. | Improved HPLC determination of phenolic compounds in cv. golden delicious apples using a monolithic column. | 2004 | J. Agric. Food Chem. | pmid:14709005 |