| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alcohol-Related Disorders | D019973 | 3 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Urinary Incontinence | D014549 | 4 associated lipids |
| Hepatitis, Alcoholic | D006519 | 5 associated lipids |
| Dyspepsia | D004415 | 5 associated lipids |
| Hypertension, Renovascular | D006978 | 10 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Glucose Intolerance | D018149 | 13 associated lipids |
| Angina, Unstable | D000789 | 14 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
SCHEMBL105486
Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with SCHEMBL105486?
SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with SCHEMBL105486
PubChem Associated disorders and diseases
What pathways are associated with SCHEMBL105486
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with SCHEMBL105486?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with SCHEMBL105486?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with SCHEMBL105486?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with SCHEMBL105486?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with SCHEMBL105486?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with SCHEMBL105486
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Feng CG et al. | [Progress in research of aldose reductase inhibitors in traditional medicinal herbs]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16335816 |
| Han P et al. | [Effect of pueraria crude extreact and puerarin on ethanol-induced expression of heat shock protein 70 in embryonic mouse hippocampal cultures]. | 2005 | Zhonghua Yi Xue Za Zhi | pmid:16324368 |
| Tian H et al. | [Separation and identification of isoflavonoids in Pueraria lobata extracts and its preparations by reversed-phase capillary liquid chromatography coupled with electrospray ionization quadrupole time of flight mass spectrometry]. | 2005 | Se Pu | pmid:16350789 |
| Pan HP et al. | [Effect of puerarin on the expression of Hsp70 in the rats with cerebral injury induced by acute local ischemia]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16011103 |
| Zhao Y et al. | [Experimental study of protective effect of pueraria compound on the cerebral ischemic injury]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16011106 |
| Gao Q et al. | Improvement of ventricular mechanical properties by puerarin involves mitochondrial permeability transition in isolated rat heart during ischemia and reperfusion. | 2005 | Conf Proc IEEE Eng Med Biol Soc | pmid:17281523 |
| Wang YL et al. | [Myocardial protective effect of puerarin injection in children with severe pneumonia]. | 2005 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:16025962 |
| Zhang S et al. | Application of microdialysis technique in the traditional chinese medicine. | 2005 | Conf Proc IEEE Eng Med Biol Soc | pmid:17282072 |
| Wang B et al. | [Clinical analysis of 5 cases with acute intravascular hemolysis caused by puerarin]. | 2004 | Beijing Da Xue Xue Bao | pmid:14970887 |
| Zhang FR et al. | [Effects of puerarin on number and activity of endothelial progenitor cells from peripheral blood]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15506293 |
| Zhang Q et al. | Flow injection-chemiluminescence determination of puerarin in pharmaceutical preparations. | 2004 | J Pharm Biomed Anal | pmid:15522534 |
| Duan HJ et al. | [Effects of puerarin on renal function, expressions of MMP-2 and TIMP-2 in diabetic rats]. | 2004 | Yao Xue Xue Bao | pmid:15493832 |
| Xiao LZ et al. | [Study on the effect and mechanism of puerarin on the size of infarction in patients with acute myocardial infarction]. | 2004 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:15495821 |
| Prasain JK et al. | Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. | 2004 | J. Agric. Food Chem. | pmid:15186086 |
| Sang HF et al. | Effect of puerarin on neural function and histopathological damages after transient spinal cord ischemia in rabbits. | 2004 | Chin. J. Traumatol. | pmid:15294110 |
| Benlhabib E et al. | Effects of purified puerarin on voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. | 2004 | J Med Food | pmid:15298765 |
| Franke AA et al. | Determinants for urinary and plasma isoflavones in humans after soy intake. | 2004 | Nutr Cancer | pmid:15623460 |
| Benlhabib E et al. | Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. | 2004 | J Med Food | pmid:15298764 |
| Matkowski A | In vitro isoflavonoid production in callus from different organs of Pueraria lobata (Wild.) Ohwi. | 2004 | J. Plant Physiol. | pmid:15077633 |
| Jung DY et al. | Induction of growth hormone release by Pueraria thunbergiana BENTH. | 2004 | Horm. Metab. Res. | pmid:15002057 |