| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alcohol-Related Disorders | D019973 | 3 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Urinary Incontinence | D014549 | 4 associated lipids |
| Hepatitis, Alcoholic | D006519 | 5 associated lipids |
| Dyspepsia | D004415 | 5 associated lipids |
| Hypertension, Renovascular | D006978 | 10 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Glucose Intolerance | D018149 | 13 associated lipids |
| Angina, Unstable | D000789 | 14 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
SCHEMBL105486
Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with SCHEMBL105486?
SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with SCHEMBL105486
PubChem Associated disorders and diseases
What pathways are associated with SCHEMBL105486
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with SCHEMBL105486?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with SCHEMBL105486?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with SCHEMBL105486?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with SCHEMBL105486?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with SCHEMBL105486?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with SCHEMBL105486
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhou Y et al. | [Comparative study on pharmacological effects of various species of Pueraria]. | 1995 | Zhongguo Zhong Yao Za Zhi | pmid:8679082 |
| Liu S et al. | [A study on processing of the root of Pueraria lobata (Willd.) ohwi by HPLC]. | 1998 | Zhongguo Zhong Yao Za Zhi | pmid:12242820 |
| Wu GL et al. | [Effect of puerarin on levels of TGF-beta1 and alpha-SMA in rats with alcoholic injury liver]. | 2008 | Zhongguo Zhong Yao Za Zhi | pmid:19166018 |
| Zou GX et al. | [New method of multi-components quantitation by one marker new method for quality evaluation of Guanmaikang capsula]. | 2008 | Zhongguo Zhong Yao Za Zhi | pmid:19007008 |
| Guo D et al. | [Study on pharmacokinetics and biodistribution of pur derivative nanopaticles in mice]. | 2010 | Zhongguo Zhong Yao Za Zhi | pmid:21355276 |
| Zang HM et al. | [Experimental study of the effects of puerarin on biological characters of osteoblasts in vitro]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16494032 |
| Yang ZD et al. | [Chemical constituents in root of Hemerocallis fulva]. | 2008 | Zhongguo Zhong Yao Za Zhi | pmid:18536463 |
| Deng L et al. | [Effect of catalpol and puerarin freeze-dried powder on coagulability, hemorheology and no in rats with Qi-deficiency and blood-stasis syndrome]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22860464 |
| Liang X et al. | [Intestinal absorption effect of Angelica dahurica extract on puerarin of puerariae Lobatae Radix]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22860465 |
| Liu XY et al. | [Stability of PEGylated puerarin under different storage conditions]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23373208 |