Yi T et al. |
Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies. |
2017 |
Drug Deliv |
pmid:28165806
|
Kang H et al. |
Puerarin inhibits M2 polarization and metastasis of tumor-associated macrophages from NSCLC xenograft model via inactivating MEK/ERK 1/2 pathway. |
2017 |
Int. J. Oncol. |
pmid:28101568
|
Li X et al. |
Puerarin protects against endothelial dysfunction and end-organ damage in Ang II-induced hypertension. |
2017 |
Clin. Exp. Hypertens. |
pmid:28060542
|
Ge B et al. |
Puerarin offsets the anticoagulation effect of warfarin in rats by inducing rCyps, upregulating vitamin K epoxide reductase and inhibiting thrombomodulin. |
2017 |
Biopharm Drug Dispos |
pmid:27925234
|
Li L et al. |
Puerarin suppression of Aβ-induced primary cortical neuron death is largely dependent on ERβ. |
2017 |
Brain Res. |
pmid:27923632
|
Liu Y et al. |
Lyophilized Powder of Catalpol and Puerarin Protected Cerebral Vessels from Ischemia by Its Anti-apoptosis on Endothelial Cells. |
2017 |
Int. J. Biol. Sci. |
pmid:28367097
|
Ma X et al. |
Puerarin attenuates cisplatin-induced rat nephrotoxicity: The involvement of TLR4/NF-κB signaling pathway. |
2017 |
PLoS ONE |
pmid:28182789
|
Zheng QH et al. |
Efficacy and safety of puerarin injection in curing acute ischemic stroke: A meta-analysis of randomized controlled trials. |
2017 |
Medicine (Baltimore) |
pmid:28072733
|
Jung HW et al. |
The Root Extract of Pueraria lobata and Its Main Compound, Puerarin, Prevent Obesity by Increasing the Energy Metabolism in Skeletal Muscle. |
2017 |
Nutrients |
pmid:28054981
|
Bacanlı M et al. |
The antioxidant, cytotoxic, and antigenotoxic effects of galangin, puerarin, and ursolic acid in mammalian cells. |
2017 |
Drug Chem Toxicol |
pmid:27461151
|
Wu L et al. |
Protective Effects of Puerarin against Aβ 1-42-Induced Learning and Memory Impairments in Mice. |
2017 |
Planta Med. |
pmid:27420352
|
KopeÄná-Zapletalová M et al. |
Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities. |
2017 |
Xenobiotica |
pmid:27312150
|
Zhao J et al. |
Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI). |
2017 |
Mol. Neurobiol. |
pmid:27013468
|
Dong Z et al. |
RGD modified and PEGylated lipid nanoparticles loaded with puerarin: Formulation, characterization and protective effects on acute myocardial ischemia model. |
2017 |
Biomed. Pharmacother. |
pmid:28236703
|
Li CH et al. |
Puerarin promotes ABCA1-mediated cholesterol efflux and decreases cellular lipid accumulation in THP-1 macrophages. |
2017 |
Eur. J. Pharmacol. |
pmid:28576406
|
Li X et al. |
Puerarin and Amlodipine Improvement of D-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression. |
2017 |
Neurochem. Res. |
pmid:28831640
|
Bhuiyan MMH et al. |
Radix Puerariae modulates glutamatergic synaptic architecture and potentiates functional synaptic plasticity in primary hippocampal neurons. |
2017 |
J Ethnopharmacol |
pmid:28734961
|
Kim Y et al. |
Pharmacokinetics and Safety of DW1029M, a Botanical Drug for the Treatment of Diabetic Nephropathy, Following Single Doses in Healthy Subjects. |
2017 |
Clin Pharmacol Drug Dev |
pmid:28301092
|
Li P et al. |
In Vivo Pharmacokinetics of Puerarin via Different Drug Administration Routes Based on Middle Cerebral Artery Occlusion Model. |
2017 |
Eur J Drug Metab Pharmacokinet |
pmid:27928655
|
Wang L et al. |
Puerarin Enhances Ca2+ Reuptake and Ca2+ Content of Sarcoplasmic Reticulum in Murine Embryonic Stem Cell-Derived Cardiomyocytes via Upregulation of SERCA2a. |
2017 |
Cell. Physiol. Biochem. |
pmid:29179218
|
Wang J et al. |
Novel cationic lipid nanoparticles as an ophthalmic delivery system for multicomponent drugs: development, characterization, in vitro permeation, in vivo pharmacokinetic, and molecular dynamics studies. |
2017 |
Int J Nanomedicine |
pmid:29158673
|
Lin L et al. |
The Effects and Possible Mechanisms of Puerarin to Treat Uterine Fibrosis Induced by Ischemia-Reperfusion Injury in Rats. |
2017 |
Med. Sci. Monit. |
pmid:28704345
|
Kong H et al. |
Pharmacokinetics and Tissue Distribution Kinetics of Puerarin in Rats Using Indirect Competitive ELISA. |
2017 |
Molecules |
pmid:28587251
|
Liu X et al. |
Puerarin suppresses LPS-induced breast cancer cell migration, invasion and adhesion by blockage NF-κB and Erk pathway. |
2017 |
Biomed. Pharmacother. |
pmid:28558356
|
Tang H et al. |
Puerarin attenuates myocardial hypoxia/reoxygenation injury by inhibiting autophagy via the Akt signaling pathway. |
2017 |
Mol Med Rep |
pmid:28393209
|
Liu H et al. |
Puerarin and zinc additively prevent mandibular bone loss through inhibiting osteoclastogenesis in ovariectomized rats. |
2017 |
Histol. Histopathol. |
pmid:27966208
|
Shang Z et al. |
Rapid profiling and identification of puerarin metabolites in rat urine and plasma after oral administration by UHPLC-LTQ-Orbitrap mass spectrometer. |
2017 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:29073480
|
Deng HF et al. |
Puerarin inhibits expression of tissue factor induced by oxidative low-density lipoprotein through activating the PI3K/Akt/eNOS pathway and inhibiting activation of ERK1/2 and NF-κB. |
2017 |
Life Sci. |
pmid:29037842
|
Tan C et al. |
Puerarin Improves Vascular Insulin Resistance and Cardiovascular Remodeling in Salt-Sensitive Hypertension. |
2017 |
Am. J. Chin. Med. |
pmid:28830209
|
Zhang WG et al. |
Puerarin Induces Hepatocellular Carcinoma Cell Apoptosis Modulated by MAPK Signaling Pathways in a Dose-dependent Manner. |
2017 |
Anticancer Res. |
pmid:28739736
|
Wang K et al. |
Puerarin inhibits amyloid β-induced NLRP3 inflammasome activation in retinal pigment epithelial cells via suppressing ROS-dependent oxidative and endoplasmic reticulum stresses. |
2017 |
Exp. Cell Res. |
pmid:28583762
|
Cheng HH et al. |
Effects of puerarin on intracellular Ca and cell viability of MDCK renal tubular cells. |
2017 |
Environ. Toxicol. Pharmacol. |
pmid:28384516
|
Zhou X et al. |
Puerarin attenuates renal fibrosis by reducing oxidative stress induced-epithelial cell apoptosis via MAPK signal pathways in vivo and in vitro. |
2017 |
Ren Fail |
pmid:28335679
|
Wang X et al. |
Molecular characterization of the C-glucosylation for puerarin biosynthesis in Pueraria lobata. |
2017 |
Plant J. |
pmid:28207970
|
Hongyun H et al. |
Puerarin provides a neuroprotection against transient cerebral ischemia by attenuating autophagy at the ischemic penumbra in neurons but not in astrocytes. |
2017 |
Neurosci. Lett. |
pmid:28192195
|
Xue B et al. |
Puerarin may protect against Schwann cell damage induced by glucose fluctuation. |
2017 |
J Nat Med |
pmid:28181078
|
Li R et al. |
Puerarin exerts the protective effect against chemical induced dysmetabolism in rats. |
2016 |
Gene |
pmid:27677221
|
Loutchanwoot P et al. |
Evaluation of in vivo estrogenic potency of natural estrogen-active chemical, puerarin, on pituitary function in gonadectomized female rats. |
2016 |
Life Sci. |
pmid:27615593
|
Chen J et al. |
Puerarin affects bone biomarkers in the serum of rats with intrauterine growth restriction. |
2016 |
J Tradit Chin Med |
pmid:27400476
|
Su B et al. |
Relevance of the Pharmacokinetic and Pharmacodynamic Profiles of Puerariae lobatae Radix to Aggregation of Multi-Component Molecules in Aqueous Decoctions. |
2016 |
Molecules |
pmid:27367654
|
Zhang X et al. |
Puerarin Attenuates Cardiac Hypertrophy Partly Through Increasing Mir-15b/195 Expression and Suppressing Non-Canonical Transforming Growth Factor Beta (Tgfβ) Signal Pathway. |
2016 |
Med. Sci. Monit. |
pmid:27145790
|
Xiong N et al. |
hVMAT2: A Target of Individualized Medication for Parkinson's Disease. |
2016 |
Neurotherapeutics |
pmid:27137201
|
Cheng Y et al. |
Protective Effect of Puerarin Against Oxidative Stress Injury of Neural Cells and Related Mechanisms. |
2016 |
Med. Sci. Monit. |
pmid:27074962
|
Saraswat G et al. |
Molecular cues to the anti-implantation effect of nano-puerarin in rats. |
2016 |
Reproduction |
pmid:27026713
|
Hong XP et al. |
Puerarin Ameliorates D-Galactose Induced Enhanced Hippocampal Neurogenesis and Tau Hyperphosphorylation in Rat Brain. |
2016 |
J. Alzheimers Dis. |
pmid:26890737
|
Suthon S et al. |
Anti-osteoporotic effects of Pueraria candollei var. mirifica on bone mineral density and histomorphometry in estrogen-deficient rats. |
2016 |
J Nat Med |
pmid:26815435
|
Qiao L et al. |
A HPLC-MS/MS method for determination of 6'''-feruloylspinosin in rat plasma and tissues: Pharmacokinetics and tissue distribution study. |
2016 |
J Pharm Biomed Anal |
pmid:26780157
|
Zhao YZ et al. |
Using PG-Liposome-Based System to Enhance Puerarin Liver-Targeted Therapy for Alcohol-Induced Liver Disease. |
2016 |
AAPS PharmSciTech |
pmid:26753818
|
Huang FJ and Chan WH |
Apoptotic effects on maturation of mouse oocytes, fertilization and fetal development by puerarin. |
2016 |
Drug Chem Toxicol |
pmid:26712108
|
Cheng G et al. |
Preparation and In Vitro/In Vivo Evaluation of Puerarin Solid Self-Microemulsifying Drug Delivery System by Spherical Crystallization Technique. |
2016 |
AAPS PharmSciTech |
pmid:26694058
|