Chen X et al. |
Puerarin attenuates palmitate-induced mitochondrial dysfunction, impaired mitophagy and inflammation in L6 myotubes. |
2018 |
Life Sci. |
pmid:29802940
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Wan Q et al. |
Puerarin inhibits vascular smooth muscle cells proliferation induced by fine particulate matter via suppressing of the p38 MAPK signaling pathway. |
2018 |
BMC Complement Altern Med |
pmid:29728095
|
Deng Y et al. |
ERK5/KLF2 activation is involved in the reducing effects of puerarin on monocyte adhesion to endothelial cells and atherosclerotic lesion in apolipoprotein E-deficient mice. |
2018 |
Biochim. Biophys. Acta |
pmid:29723698
|
Lee JH et al. |
The suppressive effect of puerarin on atopic dermatitis-like skin lesions through regulation of inflammatory mediators in vitro and in vivo. |
2018 |
Biochem. Biophys. Res. Commun. |
pmid:29524423
|
Chen G et al. |
Puerarin attenuates angiotensin II-induced cardiac fibroblast proliferation via the promotion of catalase activity and the inhibition of hydrogen peroxide-dependent Rac-1 activation. |
2018 |
Chin J Nat Med |
pmid:29425589
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Hu Y et al. |
Puerarin inhibits non-small cell lung cancer cell growth via the induction of apoptosis. |
2018 |
Oncol. Rep. |
pmid:29393465
|
Zeng X et al. |
Puerarin inhibits TRPM3/miR-204 to promote MC3T3-E1 cells proliferation, differentiation and mineralization. |
2018 |
Phytother Res |
pmid:29368357
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Fu C et al. |
Puerarin protects endothelial progenitor cells from damage of angiotensin II via activation of ERK1/2‑Nrf2 signaling pathway. |
2018 |
Mol Med Rep |
pmid:29359784
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Yang B et al. |
Influence of paeoniflorin and menthol on puerarin transport across MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model. |
2018 |
J. Pharm. Pharmacol. |
pmid:29238980
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Li Y et al. |
Effect of puerarin on collagen metabolism of fibroblasts in pelvic tissue of women with pelvic organ prolapse. |
2018 |
Mol Med Rep |
pmid:29207080
|
Zhong Y et al. |
Puerarin alleviate radicular pain from lumbar disc herniation by inhibiting ERK-dependent spinal microglia activation. |
2018 |
Neuropeptides |
pmid:30466510
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Li SW et al. |
Comparison on Anticoagulation and Antiplatelet Aggregation Effects of Puerarin with Heparin Sodium and Tirofiban Hydrochloride: An In Vitro Study. |
2018 |
Chin J Integr Med |
pmid:29067595
|
Wang Y et al. |
Support Vector Regression Approach to Predict the Design Space for the Extraction Process of . |
2018 |
Molecules |
pmid:30241281
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Chen X et al. |
Puerarin acts on the skeletal muscle to improve insulin sensitivity in diabetic rats involving μ-opioid receptor. |
2018 |
Eur. J. Pharmacol. |
pmid:29061371
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Shiying L et al. |
Puerarin promoted proliferation and differentiation of dopamine-producing cells in Parkinson's animal models. |
2018 |
Biomed. Pharmacother. |
pmid:30119192
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Hou B et al. |
Puerarin Mitigates Diabetic Hepatic Steatosis and Fibrosis by Inhibiting TGF- Signaling Pathway Activation in Type 2 Diabetic Rats. |
2018 |
Oxid Med Cell Longev |
pmid:30057680
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Pang Z et al. |
Gel formation of puerarin and mechanistic study during its cooling process. |
2018 |
Int J Pharm |
pmid:30016673
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Krittanai S et al. |
Development of a colloidal gold nanoparticle-based immunochromatographic strip for the one-step detection of miroestrol and puerarin. |
2018 |
Biomed. Chromatogr. |
pmid:29972702
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Wang L et al. |
Puerarin Attenuates Osteoarthritis via Upregulating AMP-Activated Protein Kinase/Proliferator-Activated Receptor-γ Coactivator-1 Signaling Pathway in Osteoarthritis Rats. |
2018 |
Pharmacology |
pmid:29961054
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Ullah MZ et al. |
Attenuation of inflammatory pain by puerarin in animal model of inflammation through inhibition of pro-inflammatory mediators. |
2018 |
Int. Immunopharmacol. |
pmid:29909234
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Deng HF et al. |
Puerarin prevents vascular endothelial injury through suppression of NF-κB activation in LPS-challenged human umbilical vein endothelial cells. |
2018 |
Biomed. Pharmacother. |
pmid:29775893
|
Loutchanwoot P and Vortherms T |
Effects of puerarin on estrogen-regulated gene expression in gonadotropin-releasing hormone pulse generator of ovariectomized rats. |
2018 |
Steroids |
pmid:29733861
|
Liu Q et al. |
Puerarin improves methotrexate-induced renal damage by up-regulating renal expression of Oat1 and Oat3 in vivo and in vitro. |
2018 |
Biomed. Pharmacother. |
pmid:29710508
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Wei HY et al. |
Puerarin regulates neovascular glaucoma through pigment epithelium‑derived growth factor‑induced NF‑κB signaling pathway. |
2018 |
Mol Med Rep |
pmid:29620183
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Wang S et al. |
Optimization of ionic liquids-based microwave-assisted hydrolysis of puerarin and daidzein derivatives from Radix Puerariae Lobatae extract. |
2018 |
Food Chem |
pmid:29606431
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Li W et al. |
Puerarin-loaded PEG-PE micelles with enhanced anti-apoptotic effect and better pharmacokinetic profile. |
2018 |
Drug Deliv |
pmid:29587545
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Wang X et al. |
Puerarin prevents LPS-induced acute lung injury via inhibiting inflammatory response. |
2018 |
Microb. Pathog. |
pmid:29571724
|
Guo BQ et al. |
Puerarin reduces ischemia/reperfusion-induced myocardial injury in diabetic rats via upregulation of vascular endothelial growth factor A/angiotensin-1 and suppression of apoptosis. |
2018 |
Mol Med Rep |
pmid:29568939
|
Wang T et al. |
Puerarin promotes MIN6 cell survival by reducing cellular reactive oxygen species. |
2018 |
Mol Med Rep |
pmid:29568901
|
Wu JY et al. |
A microemulsion of puerarin-phospholipid complex for improving bioavailability: preparation, in vitro and in vivo evaluations. |
2018 |
Drug Dev Ind Pharm |
pmid:29513046
|
Ling C et al. |
Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury. |
2018 |
Molecules |
pmid:29498696
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Liu X et al. |
Puerarin Inhibits Proliferation and Induces Apoptosis by Upregulation of miR-16 in Bladder Cancer Cell Line T24. |
2018 |
Oncol. Res. |
pmid:29422113
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Wang HQ et al. |
Puerarin Up-regulates Methyl-CpG Binding Protein 2 Phosphorylation in Hippocampus of Vascular Dementia Rats. |
2018 |
Chin J Integr Med |
pmid:29327124
|
Zhao Q et al. |
Effects of glycyrrhizin on the pharmacokinetics of puerarin in rats. |
2018 |
Xenobiotica |
pmid:29099639
|
Liu B et al. |
Puerarin protects against heart failure induced by pressure overload through mitigation of ferroptosis. |
2018 |
Biochem. Biophys. Res. Commun. |
pmid:29427658
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Kong H et al. |
Effect of Puerarin on the Pharmacokinetics of Baicalin in Gegen Qinlian Decoction () in Mice. |
2018 |
Chin J Integr Med |
pmid:25908218
|
Wang C et al. |
Mechanism of aquaporin 4 (AQP 4) up-regulation in rat cerebral edema under hypobaric hypoxia and the preventative effect of puerarin. |
2018 |
Life Sci. |
pmid:29054452
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Slámová K et al. |
"Sweet Flavonoids": Glycosidase-Catalyzed Modifications. |
2018 |
Int J Mol Sci |
pmid:30037103
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Yi T et al. |
Enhancing both oral bioavailability and brain penetration of puerarin using borneol in combination with preparation technologies. |
2017 |
Drug Deliv |
pmid:28165806
|
Kang H et al. |
Puerarin inhibits M2 polarization and metastasis of tumor-associated macrophages from NSCLC xenograft model via inactivating MEK/ERK 1/2 pathway. |
2017 |
Int. J. Oncol. |
pmid:28101568
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Li X et al. |
Puerarin protects against endothelial dysfunction and end-organ damage in Ang II-induced hypertension. |
2017 |
Clin. Exp. Hypertens. |
pmid:28060542
|
Ge B et al. |
Puerarin offsets the anticoagulation effect of warfarin in rats by inducing rCyps, upregulating vitamin K epoxide reductase and inhibiting thrombomodulin. |
2017 |
Biopharm Drug Dispos |
pmid:27925234
|
Li L et al. |
Puerarin suppression of Aβ-induced primary cortical neuron death is largely dependent on ERβ. |
2017 |
Brain Res. |
pmid:27923632
|
Türer ÇC et al. |
The Local Effect of Puerarin on Critical-Sized Calvarial Defects. |
2017 |
J Craniofac Surg |
pmid:27922959
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Wei S et al. |
Effect of puerarin on transcriptome of astrocyte during oxygen-glucose deprivation/reoxygenation injury. |
2017 |
Mol. Cell. Biochem. |
pmid:27844252
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Cheng YF et al. |
GPR30 Activation Contributes to the Puerarin-Mediated Neuroprotection in MPP-Induced SH-SY5Y Cell Death. |
2017 |
J. Mol. Neurosci. |
pmid:27796870
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Cong X et al. |
Puerarin ameliorates heat stress-induced oxidative damage and apoptosis in bovine Sertoli cells by suppressing ROS production and upregulating Hsp72 expression. |
2017 |
Theriogenology |
pmid:27771118
|
Song X et al. |
Restoration of autophagy by puerarin in lead-exposed primary rat proximal tubular cells via regulating AMPK-mTOR signaling. |
2017 |
J. Biochem. Mol. Toxicol. |
pmid:27762461
|
Liu Y et al. |
Lyophilized Powder of Catalpol and Puerarin Protected Cerebral Vessels from Ischemia by Its Anti-apoptosis on Endothelial Cells. |
2017 |
Int. J. Biol. Sci. |
pmid:28367097
|
Sun H et al. |
Simultaneous determination of epalrestat and puerarin in rat plasma by UHPLC-MS/MS: Application to their pharmacokinetic interaction study. |
2017 |
Biomed. Chromatogr. |
pmid:27650591
|
Ma X et al. |
Puerarin attenuates cisplatin-induced rat nephrotoxicity: The involvement of TLR4/NF-κB signaling pathway. |
2017 |
PLoS ONE |
pmid:28182789
|
Zheng QH et al. |
Efficacy and safety of puerarin injection in curing acute ischemic stroke: A meta-analysis of randomized controlled trials. |
2017 |
Medicine (Baltimore) |
pmid:28072733
|
Jung HW et al. |
The Root Extract of Pueraria lobata and Its Main Compound, Puerarin, Prevent Obesity by Increasing the Energy Metabolism in Skeletal Muscle. |
2017 |
Nutrients |
pmid:28054981
|
Bacanlı M et al. |
The antioxidant, cytotoxic, and antigenotoxic effects of galangin, puerarin, and ursolic acid in mammalian cells. |
2017 |
Drug Chem Toxicol |
pmid:27461151
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Wu L et al. |
Protective Effects of Puerarin against Aβ 1-42-Induced Learning and Memory Impairments in Mice. |
2017 |
Planta Med. |
pmid:27420352
|
KopeÄná-Zapletalová M et al. |
Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities. |
2017 |
Xenobiotica |
pmid:27312150
|
Zhao J et al. |
Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI). |
2017 |
Mol. Neurobiol. |
pmid:27013468
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Dong Z et al. |
RGD modified and PEGylated lipid nanoparticles loaded with puerarin: Formulation, characterization and protective effects on acute myocardial ischemia model. |
2017 |
Biomed. Pharmacother. |
pmid:28236703
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Li CH et al. |
Puerarin promotes ABCA1-mediated cholesterol efflux and decreases cellular lipid accumulation in THP-1 macrophages. |
2017 |
Eur. J. Pharmacol. |
pmid:28576406
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Li W et al. |
Puerarin attenuates the daunorubicin-induced apoptosis of H9c2 cells by activating the PI3K/Akt signaling pathway via the inhibition of Ca2+ influx. |
2017 |
Int. J. Mol. Med. |
pmid:29039532
|
Yao Y et al. |
Puerarin inhibits β‑amyloid peptide 1‑42‑induced tau hyperphosphorylation via the Wnt/β‑catenin signaling pathway. |
2017 |
Mol Med Rep |
pmid:28990074
|
Tu YM et al. |
A high concentration of fatty acids induces TNF-α as well as NO release mediated by the P2X4 receptor, and the protective effects of puerarin in RAW264.7 cells. |
2017 |
Food Funct |
pmid:28937704
|
Zhang L et al. |
Puerarin transport across rat nasal epithelial cells and the influence of compatibility with peoniflorin and menthol. |
2017 |
Drug Des Devel Ther |
pmid:28919709
|
Zhan XQ et al. |
Puerarin promotes the viability and differentiation of MC3T3‑E1 cells by miR‑204‑regulated Runx2 upregulation. |
2017 |
Mol Med Rep |
pmid:28901520
|
Li X et al. |
Puerarin and Amlodipine Improvement of D-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression. |
2017 |
Neurochem. Res. |
pmid:28831640
|
Bhuiyan MMH et al. |
Radix Puerariae modulates glutamatergic synaptic architecture and potentiates functional synaptic plasticity in primary hippocampal neurons. |
2017 |
J Ethnopharmacol |
pmid:28734961
|
Kim Y et al. |
Pharmacokinetics and Safety of DW1029M, a Botanical Drug for the Treatment of Diabetic Nephropathy, Following Single Doses in Healthy Subjects. |
2017 |
Clin Pharmacol Drug Dev |
pmid:28301092
|
Li P et al. |
In Vivo Pharmacokinetics of Puerarin via Different Drug Administration Routes Based on Middle Cerebral Artery Occlusion Model. |
2017 |
Eur J Drug Metab Pharmacokinet |
pmid:27928655
|
Jing S et al. |
A novel electrochemical sensor based on WO nanorods-decorated poly(sodium 4-styrenesulfonate) functionalized graphene nanocomposite modified electrode for detecting of puerarin. |
2017 |
Talanta |
pmid:28738611
|
Wang L et al. |
Puerarin Enhances Ca2+ Reuptake and Ca2+ Content of Sarcoplasmic Reticulum in Murine Embryonic Stem Cell-Derived Cardiomyocytes via Upregulation of SERCA2a. |
2017 |
Cell. Physiol. Biochem. |
pmid:29179218
|
Wang J et al. |
Novel cationic lipid nanoparticles as an ophthalmic delivery system for multicomponent drugs: development, characterization, in vitro permeation, in vivo pharmacokinetic, and molecular dynamics studies. |
2017 |
Int J Nanomedicine |
pmid:29158673
|
Lin L et al. |
The Effects and Possible Mechanisms of Puerarin to Treat Uterine Fibrosis Induced by Ischemia-Reperfusion Injury in Rats. |
2017 |
Med. Sci. Monit. |
pmid:28704345
|
Kong H et al. |
Pharmacokinetics and Tissue Distribution Kinetics of Puerarin in Rats Using Indirect Competitive ELISA. |
2017 |
Molecules |
pmid:28587251
|
Liu X et al. |
Puerarin suppresses LPS-induced breast cancer cell migration, invasion and adhesion by blockage NF-κB and Erk pathway. |
2017 |
Biomed. Pharmacother. |
pmid:28558356
|
Tang H et al. |
Puerarin attenuates myocardial hypoxia/reoxygenation injury by inhibiting autophagy via the Akt signaling pathway. |
2017 |
Mol Med Rep |
pmid:28393209
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Liu H et al. |
Puerarin and zinc additively prevent mandibular bone loss through inhibiting osteoclastogenesis in ovariectomized rats. |
2017 |
Histol. Histopathol. |
pmid:27966208
|
Shang Z et al. |
Rapid profiling and identification of puerarin metabolites in rat urine and plasma after oral administration by UHPLC-LTQ-Orbitrap mass spectrometer. |
2017 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:29073480
|
Deng HF et al. |
Puerarin inhibits expression of tissue factor induced by oxidative low-density lipoprotein through activating the PI3K/Akt/eNOS pathway and inhibiting activation of ERK1/2 and NF-κB. |
2017 |
Life Sci. |
pmid:29037842
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Tan C et al. |
Puerarin Improves Vascular Insulin Resistance and Cardiovascular Remodeling in Salt-Sensitive Hypertension. |
2017 |
Am. J. Chin. Med. |
pmid:28830209
|
Zhang WG et al. |
Puerarin Induces Hepatocellular Carcinoma Cell Apoptosis Modulated by MAPK Signaling Pathways in a Dose-dependent Manner. |
2017 |
Anticancer Res. |
pmid:28739736
|
Wang K et al. |
Puerarin inhibits amyloid β-induced NLRP3 inflammasome activation in retinal pigment epithelial cells via suppressing ROS-dependent oxidative and endoplasmic reticulum stresses. |
2017 |
Exp. Cell Res. |
pmid:28583762
|
Cheng HH et al. |
Effects of puerarin on intracellular Ca and cell viability of MDCK renal tubular cells. |
2017 |
Environ. Toxicol. Pharmacol. |
pmid:28384516
|
Zhou X et al. |
Puerarin attenuates renal fibrosis by reducing oxidative stress induced-epithelial cell apoptosis via MAPK signal pathways in vivo and in vitro. |
2017 |
Ren Fail |
pmid:28335679
|
Wang X et al. |
Molecular characterization of the C-glucosylation for puerarin biosynthesis in Pueraria lobata. |
2017 |
Plant J. |
pmid:28207970
|
Hongyun H et al. |
Puerarin provides a neuroprotection against transient cerebral ischemia by attenuating autophagy at the ischemic penumbra in neurons but not in astrocytes. |
2017 |
Neurosci. Lett. |
pmid:28192195
|
Xue B et al. |
Puerarin may protect against Schwann cell damage induced by glucose fluctuation. |
2017 |
J Nat Med |
pmid:28181078
|
Li R et al. |
Puerarin exerts the protective effect against chemical induced dysmetabolism in rats. |
2016 |
Gene |
pmid:27677221
|
Loutchanwoot P et al. |
Evaluation of in vivo estrogenic potency of natural estrogen-active chemical, puerarin, on pituitary function in gonadectomized female rats. |
2016 |
Life Sci. |
pmid:27615593
|
Zhang X et al. |
Puerarin Attenuates Cardiac Hypertrophy Partly Through Increasing Mir-15b/195 Expression and Suppressing Non-Canonical Transforming Growth Factor Beta (Tgfβ) Signal Pathway. |
2016 |
Med. Sci. Monit. |
pmid:27145790
|
Xiong N et al. |
hVMAT2: A Target of Individualized Medication for Parkinson's Disease. |
2016 |
Neurotherapeutics |
pmid:27137201
|
Cheng Y et al. |
Protective Effect of Puerarin Against Oxidative Stress Injury of Neural Cells and Related Mechanisms. |
2016 |
Med. Sci. Monit. |
pmid:27074962
|
Saraswat G et al. |
Molecular cues to the anti-implantation effect of nano-puerarin in rats. |
2016 |
Reproduction |
pmid:27026713
|
Xue Q et al. |
Lyophilized Powder of Catalpol and Puerarin Protects Neurovascular Unit from Stroke. |
2016 |
Int. J. Biol. Sci. |
pmid:27019622
|
Ma Y et al. |
Puerarin Attenuates Anoxia/Reoxygenation Injury Through Enhancing Bcl-2 Associated Athanogene 3 Expression, a Modulator of Apoptosis and Autophagy. |
2016 |
Med. Sci. Monit. |
pmid:27011313
|
Qiao L et al. |
A HPLC-MS/MS method for determination of 6'''-feruloylspinosin in rat plasma and tissues: Pharmacokinetics and tissue distribution study. |
2016 |
J Pharm Biomed Anal |
pmid:26780157
|
Zhao YZ et al. |
Using PG-Liposome-Based System to Enhance Puerarin Liver-Targeted Therapy for Alcohol-Induced Liver Disease. |
2016 |
AAPS PharmSciTech |
pmid:26753818
|
Huang FJ and Chan WH |
Apoptotic effects on maturation of mouse oocytes, fertilization and fetal development by puerarin. |
2016 |
Drug Chem Toxicol |
pmid:26712108
|
Cheng G et al. |
Preparation and In Vitro/In Vivo Evaluation of Puerarin Solid Self-Microemulsifying Drug Delivery System by Spherical Crystallization Technique. |
2016 |
AAPS PharmSciTech |
pmid:26694058
|
Liu X et al. |
Puerarin ameliorates cognitive deficits in streptozotocin-induced diabetic rats. |
2016 |
Metab Brain Dis |
pmid:26686502
|
Liu CM et al. |
Puerarin protects mouse liver against nickel-induced oxidative stress and inflammation associated with the TLR4/p38/CREB pathway. |
2016 |
Chem. Biol. Interact. |
pmid:26607348
|