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Pueraria mirifica extract and puerarin enhance proliferation and expression of alkaline phosphatase and type I collagen in primary baboon osteoblasts. |
2014 |
Phytomedicine |
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Hou JY et al. |
Mucoadhesive microparticles for gastroretentive delivery: preparation, biodistribution and targeting evaluation. |
2014 |
Mar Drugs |
pmid:25470180
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Wang J et al. |
Puerarin attenuates airway inflammation by regulation of eotaxin-3. |
2015 |
Immunol. Lett. |
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Wang X et al. |
De novo transcriptome sequencing in Pueraria lobata to identify putative genes involved in isoflavones biosynthesis. |
2015 |
Plant Cell Rep. |
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Guo HD et al. |
Large scale purification of puerarin from Puerariae Lobatae Radix through resins adsorption and acid hydrolysis. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Li B et al. |
Puerarin enhances bone mass by promoting osteoblastogenesis and slightly lowering bone marrow adiposity in ovariectomized rats. |
2014 |
Biol. Pharm. Bull. |
pmid:25590084
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Qu J et al. |
Puerarin alleviates noise-induced hearing loss via affecting PKCγ and GABAB receptor expression. |
2015 |
J. Neurol. Sci. |
pmid:25592416
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Zhu X et al. |
The effect of puerarin against IL-1β-mediated leukostasis and apoptosis in retinal capillary endothelial cells (TR-iBRB2). |
2014 |
Mol. Vis. |
pmid:25593509
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Kang OH et al. |
Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes. |
2015 |
Int. J. Mol. Med. |
pmid:25605057
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Yang X et al. |
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis. |
2015 |
J. Periodont. Res. |
pmid:25645818
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Zhang Y et al. |
The Puerarin improves renal function in STZ-induced diabetic rats by attenuating eNOS expression. |
2015 |
Ren Fail |
pmid:25707518
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Wang Z et al. |
Protective effects of edaravone combined puerarin on inhalation lung injury induced by black gunpowder smog. |
2015 |
Int. Immunopharmacol. |
pmid:25754765
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Han P et al. |
Puerarin suppresses high glucose-induced MCP-1 expression via modulating histone methylation in cultured endothelial cells. |
2015 |
Life Sci. |
pmid:25817234
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Zheng G et al. |
Effects of puerarin on lipid accumulation and metabolism in high-fat diet-fed mice. |
2015 |
PLoS ONE |
pmid:25822741
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Gray SL et al. |
Impact of kudzu and puerarin on sperm function. |
2015 |
Reprod. Toxicol. |
pmid:25828059
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Cui SQ et al. |
Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning. |
2015 |
Braz. J. Med. Biol. Res. |
pmid:25831201
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Zou ZJ et al. |
Intervention effects of puerarin on blood stasis in rats revealed by a (1)H NMR-based metabonomic approach. |
2015 |
Phytomedicine |
pmid:25837270
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Lv H et al. |
Puerarin enhances proliferation and osteoblastic differentiation of human bone marrow stromal cells via a nitric oxide/cyclic guanosine monophosphate signaling pathway. |
2015 |
Mol Med Rep |
pmid:25892538
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Kong H et al. |
Effect of Puerarin on the Pharmacokinetics of Baicalin in Gegen Qinlian Decoction () in Mice. |
2018 |
Chin J Integr Med |
pmid:25908218
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Liu AC et al. |
Pre-treatment with puerarin affects pharmacokinetics of warfarin, but not clopidogrel, in experimental rats. |
2015 |
Chin J Nat Med |
pmid:25908622
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Zhao J et al. |
Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2. |
2016 |
Mol. Neurobiol. |
pmid:25952544
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Sun D et al. |
Simultaneous determination of acetylpuerarin and puerarin in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study following intravenous and oral administration. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26021848
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Wenjun H et al. |
The Protective Effect of Puerarin on Myocardial Infarction Reperfusion Injury (MIRI): A Meta-Analysis of Randomized Studies in Rat Models. |
2015 |
Med. Sci. Monit. |
pmid:26067875
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Cheng W et al. |
Puerarin improves cardiac function through regulation of energy metabolism in Streptozotocin-Nicotinamide induced diabetic mice after myocardial infarction. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26079885
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Yi Y et al. |
The construction of puerarin nanocrystals and its pharmacokinetic and in vivo-in vitro correlation (IVIVC) studies on beagle dog. |
2015 |
Colloids Surf B Biointerfaces |
pmid:26099971
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Yu D et al. |
Puerarin attenuates glucocorticoid-induced apoptosis of hFOB1.19 cells through the JNK- and Akt-mediated mitochondrial apoptotic pathways. |
2015 |
Int. J. Mol. Med. |
pmid:26101183
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Gang C et al. |
Puerarin Suppresses Angiotensin II-Induced Cardiac Hypertrophy by Inhibiting NADPH Oxidase Activation and Oxidative Stress-Triggered AP-1 Signaling Pathways. |
2015 |
J Pharm Pharm Sci |
pmid:26158288
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Liu B et al. |
Puerarin prevents cardiac hypertrophy induced by pressure overload through activation of autophagy. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26188094
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Zhang J et al. |
Puerarin attenuates cognitive dysfunction and oxidative stress in vascular dementia rats induced by chronic ischemia. |
2015 |
Int J Clin Exp Pathol |
pmid:26191159
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Haque Bhuiyan MM et al. |
The neuritogenic and synaptogenic effects of the ethanolic extract of radix Puerariae in cultured rat hippocampal neurons. |
2015 |
J Ethnopharmacol |
pmid:26196403
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Pan X et al. |
Effect of Puerarin on Expression of ICAM-1 and TNF-α in Kidneys of Diabetic Rats. |
2015 |
Med. Sci. Monit. |
pmid:26201474
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Zhang F et al. |
Puerarin attenuates smoke inhalation injury by regulation of Th1/Th2 expression and inhibition of Th17 cells in rats. |
2015 |
Int. Immunopharmacol. |
pmid:26218281
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Zhu X et al. |
Puerarin Protects Human Neuroblastoma SH-SY5Y Cells against Glutamate-Induced Oxidative Stress and Mitochondrial Dysfunction. |
2016 |
J. Biochem. Mol. Toxicol. |
pmid:26277993
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Yin M et al. |
Puerarin Suppresses the Self-Renewal of Murine Embryonic Stem Cells by Inhibition of REST-MiR-21 Regulatory Pathway. |
2015 |
Cell. Physiol. Biochem. |
pmid:26330232
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Zhai Y et al. |
Preparation and Characterization of Puerarin-Loaded Lipid Nanocapsules. |
2015 |
J Nanosci Nanotechnol |
pmid:26353476
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Wu S et al. |
Study of the Biotransformation of Tongmai Formula by Human Intestinal Flora and Its Intestinal Permeability across the Caco-2 Cell Monolayer. |
2015 |
Molecules |
pmid:26501241
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Zhao SS et al. |
Puerarin attenuates learning and memory impairments and inhibits oxidative stress in STZ-induced SAD mice. |
2015 |
Neurotoxicology |
pmid:26511841
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Liu S et al. |
Puerarin attenuates severe burn-induced acute myocardial injury in rats. |
2015 |
Burns |
pmid:26514700
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Wang D et al. |
Evaluation of kudzu root extract-induced hepatotoxicity. |
2015 |
J Ethnopharmacol |
pmid:26545459
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Wang D et al. |
Automated On-Line Microdialysis Sampling Coupled with HPLC for Synchronous Determination of Puerarin in Subcutaneous Tissue and Plasma Following Topical Administration. |
2015 |
Clin. Lab. |
pmid:26554250
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Zhang H et al. |
Puerarin Inhibits oxLDL-Induced Macrophage Activation and Foam Cell Formation in Human THP1 Macrophage. |
2015 |
Biomed Res Int |
pmid:26576421
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Liu CM et al. |
Puerarin protects mouse liver against nickel-induced oxidative stress and inflammation associated with the TLR4/p38/CREB pathway. |
2016 |
Chem. Biol. Interact. |
pmid:26607348
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Liu X et al. |
Puerarin ameliorates cognitive deficits in streptozotocin-induced diabetic rats. |
2016 |
Metab Brain Dis |
pmid:26686502
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Cheng G et al. |
Preparation and In Vitro/In Vivo Evaluation of Puerarin Solid Self-Microemulsifying Drug Delivery System by Spherical Crystallization Technique. |
2016 |
AAPS PharmSciTech |
pmid:26694058
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Huang FJ and Chan WH |
Apoptotic effects on maturation of mouse oocytes, fertilization and fetal development by puerarin. |
2016 |
Drug Chem Toxicol |
pmid:26712108
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Zhao YZ et al. |
Using PG-Liposome-Based System to Enhance Puerarin Liver-Targeted Therapy for Alcohol-Induced Liver Disease. |
2016 |
AAPS PharmSciTech |
pmid:26753818
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Qiao L et al. |
A HPLC-MS/MS method for determination of 6'''-feruloylspinosin in rat plasma and tissues: Pharmacokinetics and tissue distribution study. |
2016 |
J Pharm Biomed Anal |
pmid:26780157
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Yang L et al. |
Puerarin Protects Pancreatic β-Cells in Obese Diabetic Mice via Activation of GLP-1R Signaling. |
2016 |
Mol. Endocrinol. |
pmid:26789107
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Suthon S et al. |
Anti-osteoporotic effects of Pueraria candollei var. mirifica on bone mineral density and histomorphometry in estrogen-deficient rats. |
2016 |
J Nat Med |
pmid:26815435
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Chang BY et al. |
Protective activity of kudzu (Pueraria thunbergiana) vine on chemically-induced hepatotoxicity: in vitro and in vivo studies. |
2016 |
BMC Complement Altern Med |
pmid:26825303
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Li W et al. |
Puerarin Improves Diabetic Aorta Injury by Inhibiting NADPH Oxidase-Derived Oxidative Stress in STZ-Induced Diabetic Rats. |
2016 |
J Diabetes Res |
pmid:26881260
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Hong XP et al. |
Puerarin Ameliorates D-Galactose Induced Enhanced Hippocampal Neurogenesis and Tau Hyperphosphorylation in Rat Brain. |
2016 |
J. Alzheimers Dis. |
pmid:26890737
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Liu B et al. |
Puerarin for ischaemic stroke. |
2016 |
Cochrane Database Syst Rev |
pmid:26891451
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Xu X et al. |
Puerarin reduces apoptosis in rat hippocampal neurons culturea in high glucose medium by modulating the p38 mitogen activated protein kinase and c-Jun N-terminal kinase signaling pathways. |
2016 |
J Tradit Chin Med |
pmid:26946623
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Su HF et al. |
Absorptive interactions of concurrent oral administration of (+)-catechin and puerarin in rats and the underlying mechanisms. |
2016 |
Acta Pharmacol. Sin. |
pmid:26972494
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Jiang QD and Li XP |
Effect of puerarin on the expression of NMU, NPY, and POMC genes in the hypothalamus. |
2016 |
Genet. Mol. Res. |
pmid:26985919
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Qu H et al. |
Rapid lateral-flow immunoassay for the quantum dot-based detection of puerarin. |
2016 |
Biosens Bioelectron |
pmid:26991602
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Hu Y et al. |
Inhibitory effect of puerarin on vascular smooth muscle cells proliferation induced by oxidised low-density lipoprotein via suppressing ERK 1/2 phosphorylation and PCNA expression. |
2016 |
Pharmazie |
pmid:27004373
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Luo X et al. |
Puerarin Exerts a Delayed Inhibitory Effect on the Proliferation of Cardiomyocytes Derived from Murine ES Cells via Slowing Progression through G2/M Phase. |
2016 |
Cell. Physiol. Biochem. |
pmid:27008508
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Ma Y et al. |
Puerarin Attenuates Anoxia/Reoxygenation Injury Through Enhancing Bcl-2 Associated Athanogene 3 Expression, a Modulator of Apoptosis and Autophagy. |
2016 |
Med. Sci. Monit. |
pmid:27011313
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Zhao J et al. |
Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI). |
2017 |
Mol. Neurobiol. |
pmid:27013468
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Xue Q et al. |
Lyophilized Powder of Catalpol and Puerarin Protects Neurovascular Unit from Stroke. |
2016 |
Int. J. Biol. Sci. |
pmid:27019622
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Saraswat G et al. |
Molecular cues to the anti-implantation effect of nano-puerarin in rats. |
2016 |
Reproduction |
pmid:27026713
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Cheng Y et al. |
Protective Effect of Puerarin Against Oxidative Stress Injury of Neural Cells and Related Mechanisms. |
2016 |
Med. Sci. Monit. |
pmid:27074962
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Yuan SY et al. |
Puerarin prevents bone loss in ovariectomized mice and inhibits osteoclast formation in vitro. |
2016 |
Chin J Nat Med |
pmid:27114313
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Wang ZK et al. |
Alleviation of Lead-Induced Apoptosis by Puerarin via Inhibiting Mitochondrial Permeability Transition Pore Opening in Primary Cultures of Rat Proximal Tubular Cells. |
2016 |
Biol Trace Elem Res |
pmid:27116952
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Wang Q et al. |
WITHDRAWN: Puerarin injection for unstable angina pectoris. |
2016 |
Cochrane Database Syst Rev |
pmid:27136749
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Xiong N et al. |
hVMAT2: A Target of Individualized Medication for Parkinson's Disease. |
2016 |
Neurotherapeutics |
pmid:27137201
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Zhang X et al. |
Puerarin Attenuates Cardiac Hypertrophy Partly Through Increasing Mir-15b/195 Expression and Suppressing Non-Canonical Transforming Growth Factor Beta (Tgfβ) Signal Pathway. |
2016 |
Med. Sci. Monit. |
pmid:27145790
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Liu G et al. |
Recent Advances in Methods of Puerarin Biotransformation. |
2016 |
Mini Rev Med Chem |
pmid:27145856
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Wang C et al. |
Puerarin attenuates inflammation and oxidation in mice with collagen antibody-induced arthritis via TLR4/NF-κB signaling. |
2016 |
Mol Med Rep |
pmid:27278131
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KopeÄná-Zapletalová M et al. |
Interaction of isoflavonoids with human liver microsomal cytochromes P450: inhibition of CYP enzyme activities. |
2017 |
Xenobiotica |
pmid:27312150
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Xu X et al. |
Puerarin, isolated from Pueraria lobata (Willd.), protects against diabetic nephropathy by attenuating oxidative stress. |
2016 |
Gene |
pmid:27317894
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Wang S et al. |
Puerarin protects against CCl4-induced liver fibrosis in mice: possible role of PARP-1 inhibition. |
2016 |
Int. Immunopharmacol. |
pmid:27318789
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Wu H et al. |
Puerarin Exerts an Antiinflammatory Effect by Inhibiting NF-kB and MAPK Activation in Staphylococcus aureus-Induced Mastitis. |
2016 |
Phytother Res |
pmid:27335240
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Su B et al. |
Relevance of the Pharmacokinetic and Pharmacodynamic Profiles of Puerariae lobatae Radix to Aggregation of Multi-Component Molecules in Aqueous Decoctions. |
2016 |
Molecules |
pmid:27367654
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Chen J et al. |
Puerarin affects bone biomarkers in the serum of rats with intrauterine growth restriction. |
2016 |
J Tradit Chin Med |
pmid:27400476
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Wang K et al. |
Neuroprotective Effect of Puerarin on Glutamate-Induced Cytotoxicity in Differentiated Y-79 Cells via Inhibition of ROS Generation and Ca(2+) Influx. |
2016 |
Int J Mol Sci |
pmid:27409614
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Wu L et al. |
Protective Effects of Puerarin against Aβ 1-42-Induced Learning and Memory Impairments in Mice. |
2017 |
Planta Med. |
pmid:27420352
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Bacanlı M et al. |
The antioxidant, cytotoxic, and antigenotoxic effects of galangin, puerarin, and ursolic acid in mammalian cells. |
2017 |
Drug Chem Toxicol |
pmid:27461151
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Zhang L et al. |
Puerarin transport across a Calu-3 cell monolayer - an in vitro model of nasal mucosa permeability and the influence of paeoniflorin and menthol. |
2016 |
Drug Des Devel Ther |
pmid:27468226
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Huang J et al. |
Different Flavonoids Can Shape Unique Gut Microbiota Profile In Vitro. |
2016 |
J. Food Sci. |
pmid:27472307
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Ji L et al. |
Puerarin inhibits the inflammatory response in atherosclerosis via modulation of the NF-κB pathway in a rabbit model. |
2016 |
Pharmacol Rep |
pmid:27505855
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Lv B et al. |
Puerarin Attenuates N-Methyl-D-aspartic Acid-induced Apoptosis and Retinal Ganglion Cell Damage Through the JNK/p38 MAPK Pathway. |
2016 |
J. Glaucoma |
pmid:27552519
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Zhang D et al. |
The Neuroprotective Effect of Puerarin in Acute Spinal Cord Injury Rats. |
2016 |
Cell. Physiol. Biochem. |
pmid:27576607
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Qin H et al. |
Puerarin Suppresses Na+-K+-ATPase-Mediated Systemic Inflammation and CD36 Expression, and Alleviates Cardiac Lipotoxicity In Vitro and In Vivo. |
2016 |
J. Cardiovasc. Pharmacol. |
pmid:27606935
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Zhao L et al. |
Protective Effects of Genistein and Puerarin against Chronic Alcohol-Induced Liver Injury in Mice via Antioxidant, Anti-inflammatory, and Anti-apoptotic Mechanisms. |
2016 |
J. Agric. Food Chem. |
pmid:27609057
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Loutchanwoot P et al. |
Evaluation of in vivo estrogenic potency of natural estrogen-active chemical, puerarin, on pituitary function in gonadectomized female rats. |
2016 |
Life Sci. |
pmid:27615593
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Wang C et al. |
Protective effects of puerarin on acute lung and cerebrum injury induced by hypobaric hypoxia via the regulation of aquaporin (AQP) via NF-κB signaling pathway. |
2016 |
Int. Immunopharmacol. |
pmid:27643664
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Sun H et al. |
Simultaneous determination of epalrestat and puerarin in rat plasma by UHPLC-MS/MS: Application to their pharmacokinetic interaction study. |
2017 |
Biomed. Chromatogr. |
pmid:27650591
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Li R et al. |
Puerarin exerts the protective effect against chemical induced dysmetabolism in rats. |
2016 |
Gene |
pmid:27677221
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Liu H et al. |
Coadministration of puerarin (low dose) and zinc attenuates bone loss and suppresses bone marrow adiposity in ovariectomized rats. |
2016 |
Life Sci. |
pmid:27697446
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Song XB et al. |
Puerarin protects against cadmium-induced proximal tubular cell apoptosis by restoring mitochondrial function. |
2016 |
Chem. Biol. Interact. |
pmid:27717697
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Gao Y et al. |
An isoflavonoid-enriched extract from Pueraria lobata (kudzu) root protects human umbilical vein endothelial cells against oxidative stress induced apoptosis. |
2016 |
J Ethnopharmacol |
pmid:27717903
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Xu H et al. |
The Effects of Puerarin on Rat Ventricular Myocytes and the Potential Mechanism. |
2016 |
Sci Rep |
pmid:27762288
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Song X et al. |
Restoration of autophagy by puerarin in lead-exposed primary rat proximal tubular cells via regulating AMPK-mTOR signaling. |
2017 |
J. Biochem. Mol. Toxicol. |
pmid:27762461
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Cong X et al. |
Puerarin ameliorates heat stress-induced oxidative damage and apoptosis in bovine Sertoli cells by suppressing ROS production and upregulating Hsp72 expression. |
2017 |
Theriogenology |
pmid:27771118
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Cheng YF et al. |
GPR30 Activation Contributes to the Puerarin-Mediated Neuroprotection in MPP-Induced SH-SY5Y Cell Death. |
2017 |
J. Mol. Neurosci. |
pmid:27796870
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Ji Y et al. |
Anticerebral Ischemia-Reperfusion Injury Activity of Synthesized Puerarin Derivatives. |
2016 |
Biomed Res Int |
pmid:27807543
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Wei S et al. |
Effect of puerarin on transcriptome of astrocyte during oxygen-glucose deprivation/reoxygenation injury. |
2017 |
Mol. Cell. Biochem. |
pmid:27844252
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