SCHEMBL105486

Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with SCHEMBL105486?

SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with SCHEMBL105486

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Arthritis D001168 41 associated lipids
Body Weight D001835 333 associated lipids
Burns D002056 34 associated lipids
Cataract D002386 34 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Coronary Disease D003327 70 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Dyspepsia D004415 5 associated lipids
Endometriosis D004715 29 associated lipids
Fatty Liver D005234 48 associated lipids
Per page 10 20 50 | Total 43

PubChem Associated disorders and diseases

What pathways are associated with SCHEMBL105486

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with SCHEMBL105486?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with SCHEMBL105486?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with SCHEMBL105486?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with SCHEMBL105486?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with SCHEMBL105486?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with SCHEMBL105486

Download all related citations
Per page 10 20 50 100 | Total 919
Authors Title Published Journal PubMed Link
Peng XY et al. [Study on the differentiation and apoptosis of HL-60 cell line induced by Puerarin]. 2001 Hunan Yi Ke Da Xue Xue Bao pmid:12536642
Dong LP et al. [The protective effect of puerarin on cultured rat cerebral cortical astrocytes]. 2001 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21171401
Chen G et al. Determination of puerarin, daidzein and rutin in Pueraria lobata (Wild.) Ohwi by capillary electrophoresis with electrochemical detection. 2001 J Chromatogr A pmid:11510548
Chen B et al. [The rapid analysis of functional components of P. Lobata by near infrared spectrum]. 2002 Guang Pu Xue Yu Guang Pu Fen Xi pmid:12914179
Cervellati R et al. Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method. 2002 J. Agric. Food Chem. pmid:12475261
Benlhabib E et al. Composition, red blood cell uptake, and serum protein binding of phytoestrogens extracted from commercial kudzu-root and soy preparations. 2002 J Med Food pmid:12495583
Keyler DE et al. Toxicity study of an antidipsotropic Chinese herbal mixture in rats: NPI-028. 2002 J Altern Complement Med pmid:12006125
Yu BS et al. RP-HPLC determination of puerarin in Chinese traditional medicinal preparations containing pueraria. 2002 J Pharm Biomed Anal pmid:12367710
Hsieh MT et al. Effects of puerarin on scopolamine-, mecamylamine-, p-chloroamphetamine- and dizocilpine-induced inhibitory avoidance performance impairment in rats. 2002 Planta Med. pmid:12391553
Choo MK et al. Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microflora. 2002 Biol. Pharm. Bull. pmid:12392089