Loutchanwoot P et al. |
Evaluation of in vivo estrogenic potency of natural estrogen-active chemical, puerarin, on pituitary function in gonadectomized female rats. |
2016 |
Life Sci. |
pmid:27615593
|
Xu ME et al. |
The study of anti-metabolic syndrome effect of puerarin in vitro. |
2005 |
Life Sci. |
pmid:16005472
|
Yan LP et al. |
Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats. |
2006 |
Life Sci. |
pmid:16472823
|
Han P et al. |
Puerarin suppresses high glucose-induced MCP-1 expression via modulating histone methylation in cultured endothelial cells. |
2015 |
Life Sci. |
pmid:25817234
|
Gao Q et al. |
Atractyloside and 5-hydroxydecanoate block the protective effect of puerarin in isolated rat heart. |
2006 |
Life Sci. |
pmid:16458326
|
Chen X et al. |
Puerarin attenuates palmitate-induced mitochondrial dysfunction, impaired mitophagy and inflammation in L6 myotubes. |
2018 |
Life Sci. |
pmid:29802940
|
Wang C et al. |
Mechanism of aquaporin 4 (AQP 4) up-regulation in rat cerebral edema under hypobaric hypoxia and the preventative effect of puerarin. |
2018 |
Life Sci. |
pmid:29054452
|
Deng HF et al. |
Puerarin inhibits expression of tissue factor induced by oxidative low-density lipoprotein through activating the PI3K/Akt/eNOS pathway and inhibiting activation of ERK1/2 and NF-κB. |
2017 |
Life Sci. |
pmid:29037842
|
Yang R et al. |
Determination of puerarin in biological samples and its application to a pharmacokinetic study by flow-injection chemiluminescence. |
2011 Sep-Oct |
Luminescence |
pmid:21547999
|
Hou JY et al. |
Mucoadhesive microparticles for gastroretentive delivery: preparation, biodistribution and targeting evaluation. |
2014 |
Mar Drugs |
pmid:25470180
|
Rachoń D et al. |
Dietary daidzein and puerarin do not affect pituitary LH expression but exert uterotropic effects in ovariectomized rats. |
2007 |
Maturitas |
pmid:17258874
|
Cherdshewasart W and Sriwatcharakul S |
Metabolic activation promotes estrogenic activity of the phytoestrogen-rich plant. |
2008 |
Maturitas |
pmid:18313242
|
Zhang X et al. |
Puerarin Attenuates Cardiac Hypertrophy Partly Through Increasing Mir-15b/195 Expression and Suppressing Non-Canonical Transforming Growth Factor Beta (Tgfβ) Signal Pathway. |
2016 |
Med. Sci. Monit. |
pmid:27145790
|
Cheng Y et al. |
Protective Effect of Puerarin Against Oxidative Stress Injury of Neural Cells and Related Mechanisms. |
2016 |
Med. Sci. Monit. |
pmid:27074962
|
Ma Y et al. |
Puerarin Attenuates Anoxia/Reoxygenation Injury Through Enhancing Bcl-2 Associated Athanogene 3 Expression, a Modulator of Apoptosis and Autophagy. |
2016 |
Med. Sci. Monit. |
pmid:27011313
|
Pan X et al. |
Effect of Puerarin on Expression of ICAM-1 and TNF-α in Kidneys of Diabetic Rats. |
2015 |
Med. Sci. Monit. |
pmid:26201474
|
Wenjun H et al. |
The Protective Effect of Puerarin on Myocardial Infarction Reperfusion Injury (MIRI): A Meta-Analysis of Randomized Studies in Rat Models. |
2015 |
Med. Sci. Monit. |
pmid:26067875
|
Lin L et al. |
The Effects and Possible Mechanisms of Puerarin to Treat Uterine Fibrosis Induced by Ischemia-Reperfusion Injury in Rats. |
2017 |
Med. Sci. Monit. |
pmid:28704345
|
Liu M et al. |
Puerarin alleviates neuropathic pain by inhibiting neuroinflammation in spinal cord. |
2014 |
Mediators Inflamm. |
pmid:25089076
|
Gruber JV and Holtz R |
Examining the genomic influence of skin antioxidants in vitro. |
2010 |
Mediators Inflamm. |
pmid:20706672
|
Zheng QH et al. |
Efficacy and safety of puerarin injection in curing acute ischemic stroke: A meta-analysis of randomized controlled trials. |
2017 |
Medicine (Baltimore) |
pmid:28072733
|
Liu X et al. |
Puerarin ameliorates cognitive deficits in streptozotocin-induced diabetic rats. |
2016 |
Metab Brain Dis |
pmid:26686502
|
Zhang XP et al. |
Protective effects of ligustrazine, kakonein and Panax notoginsenosides on multiple organs in rats with severe acute pancreatitis. |
2010 |
Methods Find Exp Clin Pharmacol |
pmid:21225014
|
Tang F et al. |
Puerarin protects against Staphylococcus aureus-induced injury of human alveolar epithelial A549 cells via downregulating alpha-hemolysin secretion. |
2014 |
Microb. Drug Resist. |
pmid:24372183
|
Wang X et al. |
Puerarin prevents LPS-induced acute lung injury via inhibiting inflammatory response. |
2018 |
Microb. Pathog. |
pmid:29571724
|
Liu G et al. |
Recent Advances in Methods of Puerarin Biotransformation. |
2016 |
Mini Rev Med Chem |
pmid:27145856
|
Wang C et al. |
Puerarin attenuates inflammation and oxidation in mice with collagen antibody-induced arthritis via TLR4/NF-κB signaling. |
2016 |
Mol Med Rep |
pmid:27278131
|
Guo XF et al. |
Synergistic antitumor effect of puerarin combined with 5-fluorouracil on gastric carcinoma. |
2015 |
Mol Med Rep |
pmid:25434307
|
Lv H et al. |
Puerarin enhances proliferation and osteoblastic differentiation of human bone marrow stromal cells via a nitric oxide/cyclic guanosine monophosphate signaling pathway. |
2015 |
Mol Med Rep |
pmid:25892538
|
Wang J et al. |
Synergistic effects of puerarin combined with 5-fluorouracil on esophageal cancer. |
2014 |
Mol Med Rep |
pmid:25189132
|
Zhang WG et al. |
Puerarin inhibits growth and induces apoptosis in SMMC-7721 hepatocellular carcinoma cells. |
2014 |
Mol Med Rep |
pmid:25175767
|
Liang J et al. |
Puerarin inhibits caspase-3 expression in osteoblasts of diabetic rats. |
2012 |
Mol Med Rep |
pmid:22470138
|
Fu C et al. |
Puerarin protects endothelial progenitor cells from damage of angiotensin II via activation of ERK1/2‑Nrf2 signaling pathway. |
2018 |
Mol Med Rep |
pmid:29359784
|
Li Y et al. |
Effect of puerarin on collagen metabolism of fibroblasts in pelvic tissue of women with pelvic organ prolapse. |
2018 |
Mol Med Rep |
pmid:29207080
|
Yao Y et al. |
Puerarin inhibits β‑amyloid peptide 1‑42‑induced tau hyperphosphorylation via the Wnt/β‑catenin signaling pathway. |
2017 |
Mol Med Rep |
pmid:28990074
|
Zhan XQ et al. |
Puerarin promotes the viability and differentiation of MC3T3‑E1 cells by miR‑204‑regulated Runx2 upregulation. |
2017 |
Mol Med Rep |
pmid:28901520
|
Wei HY et al. |
Puerarin regulates neovascular glaucoma through pigment epithelium‑derived growth factor‑induced NF‑κB signaling pathway. |
2018 |
Mol Med Rep |
pmid:29620183
|
Guo BQ et al. |
Puerarin reduces ischemia/reperfusion-induced myocardial injury in diabetic rats via upregulation of vascular endothelial growth factor A/angiotensin-1 and suppression of apoptosis. |
2018 |
Mol Med Rep |
pmid:29568939
|
Wang T et al. |
Puerarin promotes MIN6 cell survival by reducing cellular reactive oxygen species. |
2018 |
Mol Med Rep |
pmid:29568901
|
Tang H et al. |
Puerarin attenuates myocardial hypoxia/reoxygenation injury by inhibiting autophagy via the Akt signaling pathway. |
2017 |
Mol Med Rep |
pmid:28393209
|
Jun M et al. |
Suppression of arachidonic acid metabolism and nitric oxide formation by kudzu isoflavones in murine macrophages. |
2005 |
Mol Nutr Food Res |
pmid:16254887
|
Hien TT et al. |
Molecular mechanism of suppression of MDR1 by puerarin from Pueraria lobata via NF-kappaB pathway and cAMP-responsive element transcriptional activity-dependent up-regulation of AMP-activated protein kinase in breast cancer MCF-7/adr cells. |
2010 |
Mol Nutr Food Res |
pmid:20077420
|
Teng Y et al. |
Protective effect of puerarin on diabetic retinopathy in rats. |
2009 |
Mol. Biol. Rep. |
pmid:18587665
|
Shen JG et al. |
Effects of puerarin on receptor for advanced glycation end products in nephridial tissue of streptozotocin-induced diabetic rats. |
2009 |
Mol. Biol. Rep. |
pmid:19125353
|
Wei S et al. |
Effect of puerarin on transcriptome of astrocyte during oxygen-glucose deprivation/reoxygenation injury. |
2017 |
Mol. Cell. Biochem. |
pmid:27844252
|
Zhang H et al. |
Puerarin: a novel antagonist to inward rectifier potassium channel (IK1). |
2011 |
Mol. Cell. Biochem. |
pmid:21327545
|
Yang L et al. |
Puerarin Protects Pancreatic β-Cells in Obese Diabetic Mice via Activation of GLP-1R Signaling. |
2016 |
Mol. Endocrinol. |
pmid:26789107
|
Zhao J et al. |
Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI). |
2017 |
Mol. Neurobiol. |
pmid:27013468
|
Zhao J et al. |
Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2. |
2016 |
Mol. Neurobiol. |
pmid:25952544
|
Zhu X et al. |
The effect of puerarin against IL-1β-mediated leukostasis and apoptosis in retinal capillary endothelial cells (TR-iBRB2). |
2014 |
Mol. Vis. |
pmid:25593509
|
Liao ZG et al. |
Improvement of Transmembrane Transport Mechanism Study of Imperatorin on P-Glycoprotein-Mediated Drug Transport. |
2016 |
Molecules |
pmid:27886150
|
Su B et al. |
Relevance of the Pharmacokinetic and Pharmacodynamic Profiles of Puerariae lobatae Radix to Aggregation of Multi-Component Molecules in Aqueous Decoctions. |
2016 |
Molecules |
pmid:27367654
|
Wu S et al. |
Study of the Biotransformation of Tongmai Formula by Human Intestinal Flora and Its Intestinal Permeability across the Caco-2 Cell Monolayer. |
2015 |
Molecules |
pmid:26501241
|
Shao J et al. |
Spectroscopic and molecular docking studies of the in vitro interaction between puerarin and cytochrome P450. |
2014 |
Molecules |
pmid:24743933
|
Wang Y et al. |
Support Vector Regression Approach to Predict the Design Space for the Extraction Process of . |
2018 |
Molecules |
pmid:30241281
|
Ling C et al. |
Synergistic Effects of Salvianolic Acid B and Puerarin on Cerebral Ischemia Reperfusion Injury. |
2018 |
Molecules |
pmid:29498696
|
Kong H et al. |
Pharmacokinetics and Tissue Distribution Kinetics of Puerarin in Rats Using Indirect Competitive ELISA. |
2017 |
Molecules |
pmid:28587251
|
Xu R et al. |
Two new flavones from Tridax procumbens Linn. |
2010 |
Molecules |
pmid:20877227
|
Wang YG et al. |
[High-performance capillary electrophoresis for determining the chemical compositions of Gegen and Fenge extracts]. |
2008 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:18753072
|
Cui SQ |
[Effect of puerarin in myocardial protection in rats with acute and chronic alcoholism]. |
2011 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:22200707
|
Zhang R et al. |
[Protective effect of puerarin against calcium overload after focal cerebral ischemia injury in rats]. |
2010 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:20584654
|
Maji AK et al. |
Pueraria tuberosa: a review on its phytochemical and therapeutic potential. |
2014 |
Nat. Prod. Res. |
pmid:24980468
|
Xu J et al. |
A new flavonoid glycoside from the rhizomes and roots of Smilax scobinicaulis. |
2014 |
Nat. Prod. Res. |
pmid:24483603
|
Li Q et al. |
Effect of puerarin on the expression of extracellular matrix in rats with streptozotocin-induced diabetic nephropathy. |
2009 Jan-Feb |
Natl Med J India |
pmid:19761151
|
Yan LP et al. |
Analysis of the mechanisms underlying the endothelium-dependent antivasoconstriction of puerarin in rat aorta. |
2009 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:19190894
|
Tao HQ et al. |
HP-β-CD-PLGA nanoparticles improve the penetration and bioavailability of puerarin and enhance the therapeutic effects on brain ischemia-reperfusion injury in rats. |
2013 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:23192284
|
Liu S et al. |
Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. |
2014 |
Neurochem. Int. |
pmid:24657446
|
Zhu G et al. |
Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death. |
2012 |
Neurochem. Int. |
pmid:22265823
|
Liang S et al. |
P2X receptors and modulation of pain transmission: focus on effects of drugs and compounds used in traditional Chinese medicine. |
2010 |
Neurochem. Int. |
pmid:20863868
|
Wang C et al. |
Puerarin protects against β-amyloid-induced microglia apoptosis via a PI3K-dependent signaling pathway. |
2014 |
Neurochem. Res. |
pmid:25173404
|
Li X et al. |
Puerarin and Amlodipine Improvement of D-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression. |
2017 |
Neurochem. Res. |
pmid:28831640
|
Mahdy HM et al. |
Puerarin ameliorates 3-nitropropionic acid-induced neurotoxicity in rats: possible neuromodulation and antioxidant mechanisms. |
2014 |
Neurochem. Res. |
pmid:24346712
|
Gao L et al. |
Puerarin protects against ischemic brain injury in a rat model of transient focal ischemia. |
2009 |
Neurol. Res. |
pmid:19508827
|
Zhong Y et al. |
Puerarin alleviate radicular pain from lumbar disc herniation by inhibiting ERK-dependent spinal microglia activation. |
2018 |
Neuropeptides |
pmid:30466510
|
Wang N et al. |
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition. |
2014 |
Neuropharmacology |
pmid:24333675
|
Wang G et al. |
Implication of the c-Jun-NH2-terminal kinase pathway in the neuroprotective effect of puerarin against 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in PC-12 cells. |
2011 |
Neurosci. Lett. |
pmid:20934486
|
Tian F et al. |
The neuroprotective mechanism of puerarin in the treatment of acute spinal ischemia-reperfusion injury is linked to cyclin-dependent kinase 5. |
2015 |
Neurosci. Lett. |
pmid:25301568
|
Tian F et al. |
The neuroprotective mechanism of puerarin treatment of acute spinal cord injury in rats. |
2013 |
Neurosci. Lett. |
pmid:23570727
|
Hongyun H et al. |
Puerarin provides a neuroprotection against transient cerebral ischemia by attenuating autophagy at the ischemic penumbra in neurons but not in astrocytes. |
2017 |
Neurosci. Lett. |
pmid:28192195
|
Bo J et al. |
Protection by puerarin against MPP+-induced neurotoxicity in PC12 cells mediated by inhibiting mitochondrial dysfunction and caspase-3-like activation. |
2005 |
Neurosci. Res. |
pmid:16112764
|
Cheng YF et al. |
Involvement of ubiquitin proteasome system in protective mechanisms of Puerarin to MPP(+)-elicited apoptosis. |
2009 |
Neurosci. Res. |
pmid:19022306
|
Zhang X et al. |
Puerarin protects dopaminergic neurons in Parkinson's disease models. |
2014 |
Neuroscience |
pmid:25218963
|
Xiong N et al. |
hVMAT2: A Target of Individualized Medication for Parkinson's Disease. |
2016 |
Neurotherapeutics |
pmid:27137201
|
Li C et al. |
Puerarin induces the upregulation of glutathione levels and nuclear translocation of Nrf2 through PI3K/Akt/GSK-3β signaling events in PC12 cells exposed to lead. |
|
Neurotoxicol Teratol |
pmid:25195717
|
Zhao SS et al. |
Puerarin attenuates learning and memory impairments and inhibits oxidative stress in STZ-induced SAD mice. |
2015 |
Neurotoxicology |
pmid:26511841
|
Wan H et al. |
Protective effect of chuanxiongzine-puerarin in a rat model of transient middle cerebral artery occlusion-induced focal cerebral ischemia. |
2008 |
Nucl Med Commun |
pmid:18987534
|
Franke AA et al. |
Determinants for urinary and plasma isoflavones in humans after soy intake. |
2004 |
Nutr Cancer |
pmid:15623460
|
Jung HW et al. |
The Root Extract of Pueraria lobata and Its Main Compound, Puerarin, Prevent Obesity by Increasing the Energy Metabolism in Skeletal Muscle. |
2017 |
Nutrients |
pmid:28054981
|
Lipovac M et al. |
Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women. |
2011 |
Obstet Gynecol Int |
pmid:22135679
|
Hu Y et al. |
Puerarin inhibits non-small cell lung cancer cell growth via the induction of apoptosis. |
2018 |
Oncol. Rep. |
pmid:29393465
|
Liu X et al. |
Puerarin Inhibits Proliferation and Induces Apoptosis by Upregulation of miR-16 in Bladder Cancer Cell Line T24. |
2018 |
Oncol. Res. |
pmid:29422113
|
Wong RW and Rabie AB |
Effect of bio-oss collagen and collagen matrix on bone formation. |
2010 |
Open Biomed Eng J |
pmid:20461225
|
Wong RW and Rabie AB |
Effect of quercetin on preosteoblasts and bone defects. |
2008 |
Open Orthop J |
pmid:19461927
|
Wong R and Rabie B |
Effect of puerarin on bone formation. |
2007 |
Osteoarthr. Cartil. |
pmid:17379543
|
Hou B et al. |
Puerarin Mitigates Diabetic Hepatic Steatosis and Fibrosis by Inhibiting TGF- Signaling Pathway Activation in Type 2 Diabetic Rats. |
2018 |
Oxid Med Cell Longev |
pmid:30057680
|
Derda M et al. |
Plant extracts as natural amoebicidal agents. |
2009 |
Parasitol. Res. |
pmid:19050923
|
Yue PF et al. |
Preparation, characterization, and pharmacokinetic evaluation of puerarin submicron emulsion. |
2008 Jan-Feb |
PDA J Pharm Sci Technol |
pmid:18402366
|
Dong-Qin Q et al. |
Formulation development and pharmacokinetics of puerarin self-emulsifying drug delivery systems. |
2007 Jan-Feb |
PDA J Pharm Sci Technol |
pmid:17390702
|
Gu L et al. |
Polyamidomine dendrimers: an excellent drug carrier for improving the solubility and bioavailability of puerarin. |
2013 Sep-Oct |
Pharm Dev Technol |
pmid:22303809
|
Zhou A et al. |
Lymphatic transport of puerarin occurs after oral administration of different lipid-based formulations to unconscious lymph duct-cannulated rats. |
2014 |
Pharm Dev Technol |
pmid:23978005
|