Chen G et al. |
Puerarin inhibits angiotensin II-induced cardiac hypertrophy via the redox-sensitive ERK1/2, p38 and NF-κB pathways. |
2014 |
Acta Pharmacol. Sin. |
pmid:24608673
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Jung HR et al. |
Simultaneous determination of puerarin and its active metabolite in human plasma by UPLC-MS/MS: application to a pharmacokinetic study. |
2014 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:25264914
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Zhang X et al. |
Puerarin protects dopaminergic neurons in Parkinson's disease models. |
2014 |
Neuroscience |
pmid:25218963
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Fu R et al. |
Digital gene expression analysis of the pathogenesis and therapeutic mechanisms of ligustrazine and puerarin in rat atherosclerosis. |
2014 |
Gene |
pmid:25218235
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Kim MH et al. |
Mechanisms of action of phytochemicals from medicinal herbs in the treatment of Alzheimer's disease. |
2014 |
Planta Med. |
pmid:25210998
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Wang J et al. |
Synergistic effects of puerarin combined with 5-fluorouracil on esophageal cancer. |
2014 |
Mol Med Rep |
pmid:25189132
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Zhang WG et al. |
Puerarin inhibits growth and induces apoptosis in SMMC-7721 hepatocellular carcinoma cells. |
2014 |
Mol Med Rep |
pmid:25175767
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Wang C et al. |
Puerarin protects against β-amyloid-induced microglia apoptosis via a PI3K-dependent signaling pathway. |
2014 |
Neurochem. Res. |
pmid:25173404
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Xie N et al. |
Puerarin protects hippocampal neurons against cell death in pilocarpine-induced seizures through antioxidant and anti-apoptotic mechanisms. |
2014 |
Cell. Mol. Neurobiol. |
pmid:25151533
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Maji AK et al. |
Pueraria tuberosa: a review on its phytochemical and therapeutic potential. |
2014 |
Nat. Prod. Res. |
pmid:24980468
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Ma JQ et al. |
Puerarin ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney through ERK/Nrf2/ARE pathway. |
2014 |
Food Chem. Toxicol. |
pmid:24975872
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Wang C et al. |
The proliferation, differentiation, and mineralization effects of puerarin on osteoblasts in vitro. |
2014 |
Chin J Nat Med |
pmid:24969524
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Wei SY et al. |
Progress on the pharmacological research of puerarin: a review. |
2014 |
Chin J Nat Med |
pmid:24969520
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Park WS et al. |
Anti-graying effect of the extract of Pueraria thunbergiana via upregulation of cAMP/MITF-M signaling pathway. |
2014 |
J. Dermatol. Sci. |
pmid:24924521
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Yu P et al. |
Determination of puerarin in rat plasma using PEGylated magnetic carbon nanotubes by high performance liquid chromatography. |
2014 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:24768919
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Wang N et al. |
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition. |
2014 |
Neuropharmacology |
pmid:24333675
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Liu Q et al. |
MDR1 and OAT1/OAT3 mediate the drug-drug interaction between puerarin and methotrexate. |
2014 |
Pharm. Res. |
pmid:24242937
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Liu Y et al. |
Induction of adhesion molecule expression in co-culture of human bronchial epithelial cells and neutrophils suppressed by puerarin via down-regulating p38 mitogen-activated protein kinase and nuclear factor κB pathways. |
2014 |
Chin J Integr Med |
pmid:24122632
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Chen YG et al. |
Metabolic differentiations of Pueraria lobata and Pueraria thomsonii using ¹H NMR spectroscopy and multivariate statistical analysis. |
2014 |
J Pharm Biomed Anal |
pmid:23746990
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Zhu G et al. |
Neuroprotective effects of puerarin on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease model in mice. |
2014 |
Phytother Res |
pmid:23512787
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Zhou A et al. |
Lymphatic transport of puerarin occurs after oral administration of different lipid-based formulations to unconscious lymph duct-cannulated rats. |
2014 |
Pharm Dev Technol |
pmid:23978005
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Wang JW et al. |
Puerarin ameliorates oxidative stress in a rodent model of traumatic brain injury. |
2014 |
J. Surg. Res. |
pmid:24079811
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Li Z et al. |
Puerarin protects pancreatic β-cell survival via PI3K/Akt signaling pathway. |
2014 |
J. Mol. Endocrinol. |
pmid:24827001
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Zhou YX et al. |
Puerarin: a review of pharmacological effects. |
2014 |
Phytother Res |
pmid:24339367
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Zhong Y et al. |
Puerarin attenuated early diabetic kidney injury through down-regulation of matrix metalloproteinase 9 in streptozotocin-induced diabetic rats. |
2014 |
PLoS ONE |
pmid:24454919
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Bao MH et al. |
Puerarin protects endothelial cells from oxidized low density lipoprotein induced injuries via the suppression of LOX-1 and induction of eNOS. |
2014 |
Can. J. Physiol. Pharmacol. |
pmid:24708212
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Mahdy HM et al. |
The anti-apoptotic and anti-inflammatory properties of puerarin attenuate 3-nitropropionic-acid induced neurotoxicity in rats. |
2014 |
Can. J. Physiol. Pharmacol. |
pmid:24593790
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Wang XC et al. |
[Effect of chaperone-mediated autophagy in MPP(+) -induced SH-SY5Y cells and interventional effect of puerarin]. |
2014 |
Zhongguo Zhong Yao Za Zhi |
pmid:24754178
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Qu H et al. |
Development of an enzyme-linked immunosorbent assay based on anti-puerarin monoclonal antibody and its applications. |
2014 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:24583873
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Liao ZG et al. |
Transport properties of puerarin and effect of extract of Radix Angelicae dahuricae on puerarin intestinal absorption using in situ and in vitro models. |
2014 |
Phytother Res |
pmid:24756954
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Lu Q et al. |
Puerarin attenuates calcification of vascular smooth muscle cells. |
2014 |
Am. J. Chin. Med. |
pmid:24707866
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Wang Y et al. |
Simultaneous determination of four components in Baige capsule by HPLC: application to pharmacokinetics and tissue distribution of normal and middle cerebral artery occlusion rats. |
2014 |
Biomed. Chromatogr. |
pmid:24122939
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Wu M et al. |
Effects of delayed puerarin treatment in long-term neurological outcomes of focal ischemic stroke in rats. |
2014 Mar-Apr |
Indian J Pharmacol |
pmid:24741185
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Zhang H et al. |
Puerarin Inhibits oxLDL-Induced Macrophage Activation and Foam Cell Formation in Human THP1 Macrophage. |
2015 |
Biomed Res Int |
pmid:26576421
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Wu S et al. |
Study of the Biotransformation of Tongmai Formula by Human Intestinal Flora and Its Intestinal Permeability across the Caco-2 Cell Monolayer. |
2015 |
Molecules |
pmid:26501241
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Yin M et al. |
Puerarin Suppresses the Self-Renewal of Murine Embryonic Stem Cells by Inhibition of REST-MiR-21 Regulatory Pathway. |
2015 |
Cell. Physiol. Biochem. |
pmid:26330232
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Pan X et al. |
Effect of Puerarin on Expression of ICAM-1 and TNF-α in Kidneys of Diabetic Rats. |
2015 |
Med. Sci. Monit. |
pmid:26201474
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Zhang J et al. |
Puerarin attenuates cognitive dysfunction and oxidative stress in vascular dementia rats induced by chronic ischemia. |
2015 |
Int J Clin Exp Pathol |
pmid:26191159
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Wang D et al. |
Automated On-Line Microdialysis Sampling Coupled with HPLC for Synchronous Determination of Puerarin in Subcutaneous Tissue and Plasma Following Topical Administration. |
2015 |
Clin. Lab. |
pmid:26554250
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Gang C et al. |
Puerarin Suppresses Angiotensin II-Induced Cardiac Hypertrophy by Inhibiting NADPH Oxidase Activation and Oxidative Stress-Triggered AP-1 Signaling Pathways. |
2015 |
J Pharm Pharm Sci |
pmid:26158288
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Wang D et al. |
Evaluation of kudzu root extract-induced hepatotoxicity. |
2015 |
J Ethnopharmacol |
pmid:26545459
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Yu D et al. |
Puerarin attenuates glucocorticoid-induced apoptosis of hFOB1.19 cells through the JNK- and Akt-mediated mitochondrial apoptotic pathways. |
2015 |
Int. J. Mol. Med. |
pmid:26101183
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Liu S et al. |
Puerarin attenuates severe burn-induced acute myocardial injury in rats. |
2015 |
Burns |
pmid:26514700
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Cheng W et al. |
Puerarin improves cardiac function through regulation of energy metabolism in Streptozotocin-Nicotinamide induced diabetic mice after myocardial infarction. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26079885
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Zhao SS et al. |
Puerarin attenuates learning and memory impairments and inhibits oxidative stress in STZ-induced SAD mice. |
2015 |
Neurotoxicology |
pmid:26511841
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Wenjun H et al. |
The Protective Effect of Puerarin on Myocardial Infarction Reperfusion Injury (MIRI): A Meta-Analysis of Randomized Studies in Rat Models. |
2015 |
Med. Sci. Monit. |
pmid:26067875
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Zhai Y et al. |
Preparation and Characterization of Puerarin-Loaded Lipid Nanocapsules. |
2015 |
J Nanosci Nanotechnol |
pmid:26353476
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Cui SQ et al. |
Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning. |
2015 |
Braz. J. Med. Biol. Res. |
pmid:25831201
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Zheng G et al. |
Effects of puerarin on lipid accumulation and metabolism in high-fat diet-fed mice. |
2015 |
PLoS ONE |
pmid:25822741
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Zhang F et al. |
Puerarin attenuates smoke inhalation injury by regulation of Th1/Th2 expression and inhibition of Th17 cells in rats. |
2015 |
Int. Immunopharmacol. |
pmid:26218281
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Haque Bhuiyan MM et al. |
The neuritogenic and synaptogenic effects of the ethanolic extract of radix Puerariae in cultured rat hippocampal neurons. |
2015 |
J Ethnopharmacol |
pmid:26196403
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Liu B et al. |
Puerarin prevents cardiac hypertrophy induced by pressure overload through activation of autophagy. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26188094
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Yi Y et al. |
The construction of puerarin nanocrystals and its pharmacokinetic and in vivo-in vitro correlation (IVIVC) studies on beagle dog. |
2015 |
Colloids Surf B Biointerfaces |
pmid:26099971
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Guo XF et al. |
Synergistic antitumor effect of puerarin combined with 5-fluorouracil on gastric carcinoma. |
2015 |
Mol Med Rep |
pmid:25434307
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Sun D et al. |
Simultaneous determination of acetylpuerarin and puerarin in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study following intravenous and oral administration. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26021848
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Liu AC et al. |
Pre-treatment with puerarin affects pharmacokinetics of warfarin, but not clopidogrel, in experimental rats. |
2015 |
Chin J Nat Med |
pmid:25908622
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Lv H et al. |
Puerarin enhances proliferation and osteoblastic differentiation of human bone marrow stromal cells via a nitric oxide/cyclic guanosine monophosphate signaling pathway. |
2015 |
Mol Med Rep |
pmid:25892538
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Zou ZJ et al. |
Intervention effects of puerarin on blood stasis in rats revealed by a (1)H NMR-based metabonomic approach. |
2015 |
Phytomedicine |
pmid:25837270
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Gray SL et al. |
Impact of kudzu and puerarin on sperm function. |
2015 |
Reprod. Toxicol. |
pmid:25828059
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Han P et al. |
Puerarin suppresses high glucose-induced MCP-1 expression via modulating histone methylation in cultured endothelial cells. |
2015 |
Life Sci. |
pmid:25817234
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Wang Z et al. |
Protective effects of edaravone combined puerarin on inhalation lung injury induced by black gunpowder smog. |
2015 |
Int. Immunopharmacol. |
pmid:25754765
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Zhang Y et al. |
The Puerarin improves renal function in STZ-induced diabetic rats by attenuating eNOS expression. |
2015 |
Ren Fail |
pmid:25707518
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Bao L et al. |
The anti-atherosclerotic effects of puerarin on induced-atherosclerosis in rabbits. |
2015 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:24510110
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Yang X et al. |
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis. |
2015 |
J. Periodont. Res. |
pmid:25645818
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Qu J et al. |
Puerarin alleviates noise-induced hearing loss via affecting PKCγ and GABAB receptor expression. |
2015 |
J. Neurol. Sci. |
pmid:25592416
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Guo HD et al. |
Large scale purification of puerarin from Puerariae Lobatae Radix through resins adsorption and acid hydrolysis. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:25553536
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Wang X et al. |
De novo transcriptome sequencing in Pueraria lobata to identify putative genes involved in isoflavones biosynthesis. |
2015 |
Plant Cell Rep. |
pmid:25547742
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Wang J et al. |
Puerarin attenuates airway inflammation by regulation of eotaxin-3. |
2015 |
Immunol. Lett. |
pmid:25530546
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Liang XL et al. |
Mechanisms of improvement of intestinal transport of baicalin and puerarin by extracts of Radix Angelicae Dahuricae. |
2015 |
Phytother Res |
pmid:25312586
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Zhao J et al. |
Botanical drug puerarin coordinates with nerve growth factor in the regulation of neuronal survival and neuritogenesis via activating ERK1/2 and PI3K/Akt signaling pathways in the neurite extension process. |
2015 |
CNS Neurosci Ther |
pmid:25310912
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Wang P et al. |
Rapid determination of major bioactive isoflavonoid compounds during the extraction process of kudzu (Pueraria lobata) by near-infrared transmission spectroscopy. |
2015 |
Spectrochim Acta A Mol Biomol Spectrosc |
pmid:25310261
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Tian F et al. |
The neuroprotective mechanism of puerarin in the treatment of acute spinal ischemia-reperfusion injury is linked to cyclin-dependent kinase 5. |
2015 |
Neurosci. Lett. |
pmid:25301568
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Kim M et al. |
Deglycosylation of isoflavone C-glycosides by newly isolated human intestinal bacteria. |
2015 |
J. Sci. Food Agric. |
pmid:25199800
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Gan M and Yin X |
Puerarin induced in mantle cell lymphoma apoptosis and its possible mechanisms involving multi-signaling pathway. |
2015 |
Cell Biochem. Biophys. |
pmid:25173778
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Yang S et al. |
Protective effects of puerarin against tetrabromobisphenol a-induced apoptosis and cardiac developmental toxicity in zebrafish embryo-larvae. |
2015 |
Environ. Toxicol. |
pmid:24596333
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Liao D et al. |
N-trimethyl chitosan (TMC)-modified microemulsions for improved oral bioavailability of puerarin: preparation and evaluation. |
2015 |
Drug Deliv |
pmid:24467620
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Kang OH et al. |
Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes. |
2015 |
Int. J. Mol. Med. |
pmid:25605057
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Li R et al. |
Puerarin exerts the protective effect against chemical induced dysmetabolism in rats. |
2016 |
Gene |
pmid:27677221
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Zhang Y et al. |
Puerarin Prevents LPS-Induced Osteoclast Formation and Bone Loss via Inhibition of Akt Activation. |
2016 |
Biol. Pharm. Bull. |
pmid:27904045
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Liao ZG et al. |
Improvement of Transmembrane Transport Mechanism Study of Imperatorin on P-Glycoprotein-Mediated Drug Transport. |
2016 |
Molecules |
pmid:27886150
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Ji Y et al. |
Anticerebral Ischemia-Reperfusion Injury Activity of Synthesized Puerarin Derivatives. |
2016 |
Biomed Res Int |
pmid:27807543
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Zhang D et al. |
The Neuroprotective Effect of Puerarin in Acute Spinal Cord Injury Rats. |
2016 |
Cell. Physiol. Biochem. |
pmid:27576607
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Zhang L et al. |
Puerarin transport across a Calu-3 cell monolayer - an in vitro model of nasal mucosa permeability and the influence of paeoniflorin and menthol. |
2016 |
Drug Des Devel Ther |
pmid:27468226
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Wang K et al. |
Neuroprotective Effect of Puerarin on Glutamate-Induced Cytotoxicity in Differentiated Y-79 Cells via Inhibition of ROS Generation and Ca(2+) Influx. |
2016 |
Int J Mol Sci |
pmid:27409614
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Chen J et al. |
Puerarin affects bone biomarkers in the serum of rats with intrauterine growth restriction. |
2016 |
J Tradit Chin Med |
pmid:27400476
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Su B et al. |
Relevance of the Pharmacokinetic and Pharmacodynamic Profiles of Puerariae lobatae Radix to Aggregation of Multi-Component Molecules in Aqueous Decoctions. |
2016 |
Molecules |
pmid:27367654
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Zhang X et al. |
Puerarin Attenuates Cardiac Hypertrophy Partly Through Increasing Mir-15b/195 Expression and Suppressing Non-Canonical Transforming Growth Factor Beta (Tgfβ) Signal Pathway. |
2016 |
Med. Sci. Monit. |
pmid:27145790
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Xiong N et al. |
hVMAT2: A Target of Individualized Medication for Parkinson's Disease. |
2016 |
Neurotherapeutics |
pmid:27137201
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Cheng Y et al. |
Protective Effect of Puerarin Against Oxidative Stress Injury of Neural Cells and Related Mechanisms. |
2016 |
Med. Sci. Monit. |
pmid:27074962
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Wang ZK et al. |
Alleviation of Lead-Induced Apoptosis by Puerarin via Inhibiting Mitochondrial Permeability Transition Pore Opening in Primary Cultures of Rat Proximal Tubular Cells. |
2016 |
Biol Trace Elem Res |
pmid:27116952
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Hu Y et al. |
Inhibitory effect of puerarin on vascular smooth muscle cells proliferation induced by oxidised low-density lipoprotein via suppressing ERK 1/2 phosphorylation and PCNA expression. |
2016 |
Pharmazie |
pmid:27004373
|
Yuan SY et al. |
Puerarin prevents bone loss in ovariectomized mice and inhibits osteoclast formation in vitro. |
2016 |
Chin J Nat Med |
pmid:27114313
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Qu H et al. |
Rapid lateral-flow immunoassay for the quantum dot-based detection of puerarin. |
2016 |
Biosens Bioelectron |
pmid:26991602
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Liu B et al. |
Puerarin for ischaemic stroke. |
2016 |
Cochrane Database Syst Rev |
pmid:26891451
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Hong XP et al. |
Puerarin Ameliorates D-Galactose Induced Enhanced Hippocampal Neurogenesis and Tau Hyperphosphorylation in Rat Brain. |
2016 |
J. Alzheimers Dis. |
pmid:26890737
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Suthon S et al. |
Anti-osteoporotic effects of Pueraria candollei var. mirifica on bone mineral density and histomorphometry in estrogen-deficient rats. |
2016 |
J Nat Med |
pmid:26815435
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Qiao L et al. |
A HPLC-MS/MS method for determination of 6'''-feruloylspinosin in rat plasma and tissues: Pharmacokinetics and tissue distribution study. |
2016 |
J Pharm Biomed Anal |
pmid:26780157
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Zhao YZ et al. |
Using PG-Liposome-Based System to Enhance Puerarin Liver-Targeted Therapy for Alcohol-Induced Liver Disease. |
2016 |
AAPS PharmSciTech |
pmid:26753818
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Huang FJ and Chan WH |
Apoptotic effects on maturation of mouse oocytes, fertilization and fetal development by puerarin. |
2016 |
Drug Chem Toxicol |
pmid:26712108
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Cheng G et al. |
Preparation and In Vitro/In Vivo Evaluation of Puerarin Solid Self-Microemulsifying Drug Delivery System by Spherical Crystallization Technique. |
2016 |
AAPS PharmSciTech |
pmid:26694058
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