| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cataract | D002386 | 34 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
| Heart Failure | D006333 | 36 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
SCHEMBL105486
Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with SCHEMBL105486?
SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with SCHEMBL105486
PubChem Associated disorders and diseases
What pathways are associated with SCHEMBL105486
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with SCHEMBL105486?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with SCHEMBL105486?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with SCHEMBL105486?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with SCHEMBL105486?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with SCHEMBL105486?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with SCHEMBL105486
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Zhao YZ et al. | Using PG-Liposome-Based System to Enhance Puerarin Liver-Targeted Therapy for Alcohol-Induced Liver Disease. | 2016 | AAPS PharmSciTech | pmid:26753818 |
| Cheng G et al. | Preparation and In Vitro/In Vivo Evaluation of Puerarin Solid Self-Microemulsifying Drug Delivery System by Spherical Crystallization Technique. | 2016 | AAPS PharmSciTech | pmid:26694058 |
| Yue PF et al. | The study on the entrapment efficiency and in vitro release of puerarin submicron emulsion. | 2009 | AAPS PharmSciTech | pmid:19381837 |
| Chen AZ et al. | Microencapsulation of puerarin nanoparticles by poly(l-lactide) in a supercritical CO(2) process. | 2009 | Acta Biomater | pmid:19463980 |
| Xu J et al. | Cyclodextrin-containing hydrogels for contact lenses as a platform for drug incorporation and release. | 2010 | Acta Biomater | pmid:19619677 |
| Zhang CP et al. | Genistein-3'-sulfonic acid dihydrate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583946 |
| Mao CP and Gu ZL | Puerarin reduces increased c-fos, c-jun, and type IV collagen expression caused by high glucose in glomerular mesangial cells. | 2005 | Acta Pharmacol. Sin. | pmid:16038632 |
| Su HF et al. | Absorptive interactions of concurrent oral administration of (+)-catechin and puerarin in rats and the underlying mechanisms. | 2016 | Acta Pharmacol. Sin. | pmid:26972494 |
| Zhu JH et al. | Effects of puerarin on number and activity of endothelial progenitor cells from peripheral blood. | 2004 | Acta Pharmacol. Sin. | pmid:15301738 |