Hou JY et al. |
Mucoadhesive microparticles for gastroretentive delivery: preparation, biodistribution and targeting evaluation. |
2014 |
Mar Drugs |
pmid:25470180
|
Tiyasatkulkovit W et al. |
Pueraria mirifica extract and puerarin enhance proliferation and expression of alkaline phosphatase and type I collagen in primary baboon osteoblasts. |
2014 |
Phytomedicine |
pmid:25442257
|
Liu M et al. |
Puerarin alleviates neuropathic pain by inhibiting neuroinflammation in spinal cord. |
2014 |
Mediators Inflamm. |
pmid:25089076
|
Wang L et al. |
Puerarin facilitates T-tubule development of murine embryonic stem cell-derived cardiomyocytes. |
2014 |
Cell. Physiol. Biochem. |
pmid:25059232
|
Qu Q et al. |
Inhibitory effects of phytochemicals on metabolic capabilities of CYP2D6(*)1 and CYP2D6(*)10 using cell-based models in vitro. |
2014 |
Acta Pharmacol. Sin. |
pmid:24786236
|
Shao J et al. |
Spectroscopic and molecular docking studies of the in vitro interaction between puerarin and cytochrome P450. |
2014 |
Molecules |
pmid:24743933
|
Liu Y et al. |
Amelioration of stroke-induced neurological deficiency by lyophilized powder of catapol and puerarin. |
2014 |
Int. J. Biol. Sci. |
pmid:24719562
|
Ma JQ et al. |
Puerarin attenuates carbon tetrachloride-induced liver oxidative stress and hyperlipidaemia in mouse by JNK/c-Jun/CYP7A1 pathway. |
2014 |
Basic Clin. Pharmacol. Toxicol. |
pmid:24698568
|
Chen G et al. |
Puerarin inhibits angiotensin II-induced cardiac hypertrophy via the redox-sensitive ERK1/2, p38 and NF-κB pathways. |
2014 |
Acta Pharmacol. Sin. |
pmid:24608673
|
Li B et al. |
Puerarin enhances bone mass by promoting osteoblastogenesis and slightly lowering bone marrow adiposity in ovariectomized rats. |
2014 |
Biol. Pharm. Bull. |
pmid:25590084
|
Jung HR et al. |
Simultaneous determination of puerarin and its active metabolite in human plasma by UPLC-MS/MS: application to a pharmacokinetic study. |
2014 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:25264914
|
Zhang X et al. |
Puerarin protects dopaminergic neurons in Parkinson's disease models. |
2014 |
Neuroscience |
pmid:25218963
|
Lu XL et al. |
Protective effects of puerarin against Aß40-induced vascular dysfunction in zebrafish and human endothelial cells. |
2014 |
Eur. J. Pharmacol. |
pmid:24690262
|
Liu S et al. |
Puerarin alleviates aggravated sympathoexcitatory response induced by myocardial ischemia via regulating P2X3 receptor in rat superior cervical ganglia. |
2014 |
Neurochem. Int. |
pmid:24657446
|
Yan Y et al. |
Simultaneous determination of puerarin, daidzin, daidzein, paeoniflorin, albiflorin, liquiritin and liquiritigenin in rat plasma and its application to a pharmacokinetic study of Ge-Gen Decoction by a liquid chromatography-electrospray ionization-tandem mass spectrometry. |
2014 |
J Pharm Biomed Anal |
pmid:24637051
|
Wang S et al. |
Efficient glycosylation of puerarin by an organic solvent-tolerant strain of Lysinibacillus fusiformis. |
2014 |
Enzyme Microb. Technol. |
pmid:24629266
|
Li H et al. |
Biopharmaceutics classification of puerarin and comparison of perfusion approaches in rats. |
2014 |
Int J Pharm |
pmid:24607203
|
She S et al. |
Effects of puerarin in STZ-induced diabetic rats by oxidative stress and the TGF-β1/Smad2 pathway. |
2014 |
Food Funct |
pmid:24595557
|
Liu G et al. |
Puerarin protects against lead-induced cytotoxicity in cultured primary rat proximal tubular cells. |
2014 |
Hum Exp Toxicol |
pmid:24505050
|
Tang L et al. |
The protective effects of puerarin in cardiomyocytes from anoxia/reoxygenation injury are mediated by PKCε. |
2014 |
Cell Biochem. Funct. |
pmid:24496955
|
Tang F et al. |
Puerarin protects against Staphylococcus aureus-induced injury of human alveolar epithelial A549 cells via downregulating alpha-hemolysin secretion. |
2014 |
Microb. Drug Resist. |
pmid:24372183
|
Zhou Y et al. |
Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice. |
2014 |
Int. J. Neuropsychopharmacol. |
pmid:24345484
|
Wang N et al. |
Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition. |
2014 |
Neuropharmacology |
pmid:24333675
|
Liu Q et al. |
MDR1 and OAT1/OAT3 mediate the drug-drug interaction between puerarin and methotrexate. |
2014 |
Pharm. Res. |
pmid:24242937
|
Yuan Y et al. |
Puerarin attenuates pressure overload-induced cardiac hypertrophy. |
2014 |
J Cardiol |
pmid:23906530
|
Li Z et al. |
Puerarin protects pancreatic β-cell survival via PI3K/Akt signaling pathway. |
2014 |
J. Mol. Endocrinol. |
pmid:24827001
|
Guo YJ et al. |
In vivo inhibitory effects of puerarin on selected rat cytochrome P450 isoenzymes. |
2014 |
Pharmazie |
pmid:24855829
|
Wu J et al. |
Efficacy and safety of puerarin injection in treatment of diabetic peripheral neuropathy: a systematic review and meta-analysis of randomized controlled trials. |
2014 |
J Tradit Chin Med |
pmid:25185357
|
Liu S et al. |
Puerarin blocks the signaling transmission mediated by P2X3 in SG and DRG to relieve myocardial ischemic damage. |
2014 |
Brain Res. Bull. |
pmid:24447636
|
Xu J et al. |
A new flavonoid glycoside from the rhizomes and roots of Smilax scobinicaulis. |
2014 |
Nat. Prod. Res. |
pmid:24483603
|
Mahdy HM et al. |
Puerarin ameliorates 3-nitropropionic acid-induced neurotoxicity in rats: possible neuromodulation and antioxidant mechanisms. |
2014 |
Neurochem. Res. |
pmid:24346712
|
Zhou YX et al. |
Puerarin: a review of pharmacological effects. |
2014 |
Phytother Res |
pmid:24339367
|
Wu M et al. |
Effects of delayed puerarin treatment in long-term neurological outcomes of focal ischemic stroke in rats. |
2014 Mar-Apr |
Indian J Pharmacol |
pmid:24741185
|
Zhang H et al. |
Puerarin Inhibits oxLDL-Induced Macrophage Activation and Foam Cell Formation in Human THP1 Macrophage. |
2015 |
Biomed Res Int |
pmid:26576421
|
Wu S et al. |
Study of the Biotransformation of Tongmai Formula by Human Intestinal Flora and Its Intestinal Permeability across the Caco-2 Cell Monolayer. |
2015 |
Molecules |
pmid:26501241
|
Yin M et al. |
Puerarin Suppresses the Self-Renewal of Murine Embryonic Stem Cells by Inhibition of REST-MiR-21 Regulatory Pathway. |
2015 |
Cell. Physiol. Biochem. |
pmid:26330232
|
Pan X et al. |
Effect of Puerarin on Expression of ICAM-1 and TNF-α in Kidneys of Diabetic Rats. |
2015 |
Med. Sci. Monit. |
pmid:26201474
|
Zhang J et al. |
Puerarin attenuates cognitive dysfunction and oxidative stress in vascular dementia rats induced by chronic ischemia. |
2015 |
Int J Clin Exp Pathol |
pmid:26191159
|
Wang D et al. |
Automated On-Line Microdialysis Sampling Coupled with HPLC for Synchronous Determination of Puerarin in Subcutaneous Tissue and Plasma Following Topical Administration. |
2015 |
Clin. Lab. |
pmid:26554250
|
Gang C et al. |
Puerarin Suppresses Angiotensin II-Induced Cardiac Hypertrophy by Inhibiting NADPH Oxidase Activation and Oxidative Stress-Triggered AP-1 Signaling Pathways. |
2015 |
J Pharm Pharm Sci |
pmid:26158288
|
Wang D et al. |
Evaluation of kudzu root extract-induced hepatotoxicity. |
2015 |
J Ethnopharmacol |
pmid:26545459
|
Yu D et al. |
Puerarin attenuates glucocorticoid-induced apoptosis of hFOB1.19 cells through the JNK- and Akt-mediated mitochondrial apoptotic pathways. |
2015 |
Int. J. Mol. Med. |
pmid:26101183
|
Liu S et al. |
Puerarin attenuates severe burn-induced acute myocardial injury in rats. |
2015 |
Burns |
pmid:26514700
|
Cheng W et al. |
Puerarin improves cardiac function through regulation of energy metabolism in Streptozotocin-Nicotinamide induced diabetic mice after myocardial infarction. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26079885
|
Zhao SS et al. |
Puerarin attenuates learning and memory impairments and inhibits oxidative stress in STZ-induced SAD mice. |
2015 |
Neurotoxicology |
pmid:26511841
|
Wenjun H et al. |
The Protective Effect of Puerarin on Myocardial Infarction Reperfusion Injury (MIRI): A Meta-Analysis of Randomized Studies in Rat Models. |
2015 |
Med. Sci. Monit. |
pmid:26067875
|
Zhai Y et al. |
Preparation and Characterization of Puerarin-Loaded Lipid Nanocapsules. |
2015 |
J Nanosci Nanotechnol |
pmid:26353476
|
Cui SQ et al. |
Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning. |
2015 |
Braz. J. Med. Biol. Res. |
pmid:25831201
|
Zheng G et al. |
Effects of puerarin on lipid accumulation and metabolism in high-fat diet-fed mice. |
2015 |
PLoS ONE |
pmid:25822741
|
Zhang F et al. |
Puerarin attenuates smoke inhalation injury by regulation of Th1/Th2 expression and inhibition of Th17 cells in rats. |
2015 |
Int. Immunopharmacol. |
pmid:26218281
|
Haque Bhuiyan MM et al. |
The neuritogenic and synaptogenic effects of the ethanolic extract of radix Puerariae in cultured rat hippocampal neurons. |
2015 |
J Ethnopharmacol |
pmid:26196403
|
Liu B et al. |
Puerarin prevents cardiac hypertrophy induced by pressure overload through activation of autophagy. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:26188094
|
Yi Y et al. |
The construction of puerarin nanocrystals and its pharmacokinetic and in vivo-in vitro correlation (IVIVC) studies on beagle dog. |
2015 |
Colloids Surf B Biointerfaces |
pmid:26099971
|
Guo XF et al. |
Synergistic antitumor effect of puerarin combined with 5-fluorouracil on gastric carcinoma. |
2015 |
Mol Med Rep |
pmid:25434307
|
Sun D et al. |
Simultaneous determination of acetylpuerarin and puerarin in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study following intravenous and oral administration. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:26021848
|
Liu AC et al. |
Pre-treatment with puerarin affects pharmacokinetics of warfarin, but not clopidogrel, in experimental rats. |
2015 |
Chin J Nat Med |
pmid:25908622
|
Lv H et al. |
Puerarin enhances proliferation and osteoblastic differentiation of human bone marrow stromal cells via a nitric oxide/cyclic guanosine monophosphate signaling pathway. |
2015 |
Mol Med Rep |
pmid:25892538
|
Zou ZJ et al. |
Intervention effects of puerarin on blood stasis in rats revealed by a (1)H NMR-based metabonomic approach. |
2015 |
Phytomedicine |
pmid:25837270
|
Gray SL et al. |
Impact of kudzu and puerarin on sperm function. |
2015 |
Reprod. Toxicol. |
pmid:25828059
|
Han P et al. |
Puerarin suppresses high glucose-induced MCP-1 expression via modulating histone methylation in cultured endothelial cells. |
2015 |
Life Sci. |
pmid:25817234
|
Wang Z et al. |
Protective effects of edaravone combined puerarin on inhalation lung injury induced by black gunpowder smog. |
2015 |
Int. Immunopharmacol. |
pmid:25754765
|
Zhang Y et al. |
The Puerarin improves renal function in STZ-induced diabetic rats by attenuating eNOS expression. |
2015 |
Ren Fail |
pmid:25707518
|
Bao L et al. |
The anti-atherosclerotic effects of puerarin on induced-atherosclerosis in rabbits. |
2015 |
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub |
pmid:24510110
|
Yang X et al. |
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis. |
2015 |
J. Periodont. Res. |
pmid:25645818
|
Qu J et al. |
Puerarin alleviates noise-induced hearing loss via affecting PKCγ and GABAB receptor expression. |
2015 |
J. Neurol. Sci. |
pmid:25592416
|
Guo HD et al. |
Large scale purification of puerarin from Puerariae Lobatae Radix through resins adsorption and acid hydrolysis. |
2015 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:25553536
|
Wang X et al. |
De novo transcriptome sequencing in Pueraria lobata to identify putative genes involved in isoflavones biosynthesis. |
2015 |
Plant Cell Rep. |
pmid:25547742
|
Wang J et al. |
Puerarin attenuates airway inflammation by regulation of eotaxin-3. |
2015 |
Immunol. Lett. |
pmid:25530546
|
Liang XL et al. |
Mechanisms of improvement of intestinal transport of baicalin and puerarin by extracts of Radix Angelicae Dahuricae. |
2015 |
Phytother Res |
pmid:25312586
|
Zhao J et al. |
Botanical drug puerarin coordinates with nerve growth factor in the regulation of neuronal survival and neuritogenesis via activating ERK1/2 and PI3K/Akt signaling pathways in the neurite extension process. |
2015 |
CNS Neurosci Ther |
pmid:25310912
|
Wang P et al. |
Rapid determination of major bioactive isoflavonoid compounds during the extraction process of kudzu (Pueraria lobata) by near-infrared transmission spectroscopy. |
2015 |
Spectrochim Acta A Mol Biomol Spectrosc |
pmid:25310261
|
Tian F et al. |
The neuroprotective mechanism of puerarin in the treatment of acute spinal ischemia-reperfusion injury is linked to cyclin-dependent kinase 5. |
2015 |
Neurosci. Lett. |
pmid:25301568
|
Kim M et al. |
Deglycosylation of isoflavone C-glycosides by newly isolated human intestinal bacteria. |
2015 |
J. Sci. Food Agric. |
pmid:25199800
|
Gan M and Yin X |
Puerarin induced in mantle cell lymphoma apoptosis and its possible mechanisms involving multi-signaling pathway. |
2015 |
Cell Biochem. Biophys. |
pmid:25173778
|
Yang S et al. |
Protective effects of puerarin against tetrabromobisphenol a-induced apoptosis and cardiac developmental toxicity in zebrafish embryo-larvae. |
2015 |
Environ. Toxicol. |
pmid:24596333
|
Liao D et al. |
N-trimethyl chitosan (TMC)-modified microemulsions for improved oral bioavailability of puerarin: preparation and evaluation. |
2015 |
Drug Deliv |
pmid:24467620
|
Kang OH et al. |
Puerarin ameliorates hepatic steatosis by activating the PPARα and AMPK signaling pathways in hepatocytes. |
2015 |
Int. J. Mol. Med. |
pmid:25605057
|
Tanaka T et al. |
Puerarin Suppresses Macrophage Activation via Antioxidant Mechanisms in a CaPO4-Induced Mouse Model of Aneurysm. |
2016 |
J. Nutr. Sci. Vitaminol. |
pmid:28202848
|
Liu H et al. |
Coadministration of puerarin (low dose) and zinc attenuates bone loss and suppresses bone marrow adiposity in ovariectomized rats. |
2016 |
Life Sci. |
pmid:27697446
|
Wang C et al. |
Protective effects of puerarin on acute lung and cerebrum injury induced by hypobaric hypoxia via the regulation of aquaporin (AQP) via NF-κB signaling pathway. |
2016 |
Int. Immunopharmacol. |
pmid:27643664
|
Tanaka T et al. |
Anti-Hyperglycemic Effect of a Kudzu (Pueraria lobata) Vine Extract in Ovariectomized Mice. |
2016 |
J. Nutr. Sci. Vitaminol. |
pmid:27928122
|
Zhao L et al. |
Protective Effects of Genistein and Puerarin against Chronic Alcohol-Induced Liver Injury in Mice via Antioxidant, Anti-inflammatory, and Anti-apoptotic Mechanisms. |
2016 |
J. Agric. Food Chem. |
pmid:27609057
|
Qin H et al. |
Puerarin Suppresses Na+-K+-ATPase-Mediated Systemic Inflammation and CD36 Expression, and Alleviates Cardiac Lipotoxicity In Vitro and In Vivo. |
2016 |
J. Cardiovasc. Pharmacol. |
pmid:27606935
|
Lv B et al. |
Puerarin Attenuates N-Methyl-D-aspartic Acid-induced Apoptosis and Retinal Ganglion Cell Damage Through the JNK/p38 MAPK Pathway. |
2016 |
J. Glaucoma |
pmid:27552519
|
Ji L et al. |
Puerarin inhibits the inflammatory response in atherosclerosis via modulation of the NF-κB pathway in a rabbit model. |
2016 |
Pharmacol Rep |
pmid:27505855
|
Wu H et al. |
Puerarin Exerts an Antiinflammatory Effect by Inhibiting NF-kB and MAPK Activation in Staphylococcus aureus-Induced Mastitis. |
2016 |
Phytother Res |
pmid:27335240
|
Wang S et al. |
Puerarin protects against CCl4-induced liver fibrosis in mice: possible role of PARP-1 inhibition. |
2016 |
Int. Immunopharmacol. |
pmid:27318789
|
Xu X et al. |
Puerarin, isolated from Pueraria lobata (Willd.), protects against diabetic nephropathy by attenuating oxidative stress. |
2016 |
Gene |
pmid:27317894
|
Wang C et al. |
Puerarin attenuates inflammation and oxidation in mice with collagen antibody-induced arthritis via TLR4/NF-κB signaling. |
2016 |
Mol Med Rep |
pmid:27278131
|
Liu G et al. |
Recent Advances in Methods of Puerarin Biotransformation. |
2016 |
Mini Rev Med Chem |
pmid:27145856
|
Wang Q et al. |
WITHDRAWN: Puerarin injection for unstable angina pectoris. |
2016 |
Cochrane Database Syst Rev |
pmid:27136749
|
Su HF et al. |
Absorptive interactions of concurrent oral administration of (+)-catechin and puerarin in rats and the underlying mechanisms. |
2016 |
Acta Pharmacol. Sin. |
pmid:26972494
|
Xu X et al. |
Puerarin reduces apoptosis in rat hippocampal neurons culturea in high glucose medium by modulating the p38 mitogen activated protein kinase and c-Jun N-terminal kinase signaling pathways. |
2016 |
J Tradit Chin Med |
pmid:26946623
|
Li W et al. |
Puerarin Improves Diabetic Aorta Injury by Inhibiting NADPH Oxidase-Derived Oxidative Stress in STZ-Induced Diabetic Rats. |
2016 |
J Diabetes Res |
pmid:26881260
|
Chang BY et al. |
Protective activity of kudzu (Pueraria thunbergiana) vine on chemically-induced hepatotoxicity: in vitro and in vivo studies. |
2016 |
BMC Complement Altern Med |
pmid:26825303
|
Yang L et al. |
Puerarin Protects Pancreatic β-Cells in Obese Diabetic Mice via Activation of GLP-1R Signaling. |
2016 |
Mol. Endocrinol. |
pmid:26789107
|
Zhu X et al. |
Puerarin Protects Human Neuroblastoma SH-SY5Y Cells against Glutamate-Induced Oxidative Stress and Mitochondrial Dysfunction. |
2016 |
J. Biochem. Mol. Toxicol. |
pmid:26277993
|
Zhao J et al. |
Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2. |
2016 |
Mol. Neurobiol. |
pmid:25952544
|
Huang J et al. |
Different Flavonoids Can Shape Unique Gut Microbiota Profile In Vitro. |
2016 |
J. Food Sci. |
pmid:27472307
|
Xu H et al. |
The Effects of Puerarin on Rat Ventricular Myocytes and the Potential Mechanism. |
2016 |
Sci Rep |
pmid:27762288
|