SCHEMBL105486

Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with SCHEMBL105486?

SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with SCHEMBL105486

MeSH term MeSH ID Detail
Endometriosis D004715 29 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Angina Pectoris D000787 27 associated lipids
Brain Infarction D020520 17 associated lipids
Angina, Unstable D000789 14 associated lipids
Glucose Intolerance D018149 13 associated lipids
Amnesia D000647 12 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Dyspepsia D004415 5 associated lipids
Hepatitis, Alcoholic D006519 5 associated lipids
Per page 10 20 50 | Total 43

PubChem Associated disorders and diseases

What pathways are associated with SCHEMBL105486

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with SCHEMBL105486?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with SCHEMBL105486?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with SCHEMBL105486?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with SCHEMBL105486?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with SCHEMBL105486?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with SCHEMBL105486

Download all related citations
Per page 10 20 50 100 | Total 919
Authors Title Published Journal PubMed Link
Shi RL and Zhang JJ [Protective effect of puerarin on vascular endothelial cell apoptosis induced by chemical hypoxia in vitro]. 2003 Yao Xue Xue Bao pmid:12778743
Li X et al. Experimental study on the protective effect of puerarin to Parkinson disease. 2003 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:12973933
Pan HP et al. [Experimental study of puerarin injection on the hemorheology in acute blood-stasis model rats]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15617506
Bae HS et al. Hepatoprotective activity of reduohanxiao-tang (yuldahanso-tang) is related to the inhibition of beta-glucuronidase. 2003 Am. J. Chin. Med. pmid:12723760
Jin WS et al. [Determination of puerarin, daidzin and daidzein in root of Pueraria lobata of different origin by HPLC]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15015267
Overstreet DH et al. NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists. 2003 Pharmacol. Biochem. Behav. pmid:12895679
Li B and Yu S [Effect of puerarin on the bone metabolism in vitro]. 2003 Beijing Da Xue Xue Bao pmid:12920814
Shi HP et al. [Culture of hairy roots in Pueraria phaseoloides and its puerarin production]. 2003 Shi Yan Sheng Wu Xue Bao pmid:14724930
Xie RQ et al. [Myocardial protection and mechanism of Puerarin Injection on patients of coronary heart disease with ischemia/reperfusion]. 2003 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:14714357
Xu XH [Effects of puerarin on fatty superoxide in aged mice induced by D-galactose]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15015271