SCHEMBL105486

Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with SCHEMBL105486?

SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with SCHEMBL105486

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Adenocarcinoma D000230 166 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 43

PubChem Associated disorders and diseases

What pathways are associated with SCHEMBL105486

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with SCHEMBL105486?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with SCHEMBL105486?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with SCHEMBL105486?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with SCHEMBL105486?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with SCHEMBL105486?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with SCHEMBL105486

Download all related citations
Per page 10 20 50 100 | Total 919
Authors Title Published Journal PubMed Link
Zhao Z et al. [Clinical study of puerarin in treatment of patients with unstable angina]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11477926
Meng P et al. [Clinical observation of the treatment of infantile viral myocarditis with puerarin]. 1999 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11783152
Chen J et al. [Effect of puerarin on fibrinolytic activity and lipid peroxide in patients with coronary heart disease]. 1999 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11783153
Ren P et al. [Observation on efficacy of puerarin in treating diabetic retinopathy]. 2000 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11789184
Shi WG et al. [Study on interventing effect of puerarin on insulin resistance in patients with coronary heart disease]. 2002 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:12585165
Yu CQ [Treatment of endometriosis by puerarin]. 2008 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:19213335
Yang S et al. [Effect of puerarin on liver injury in KKAy mice with type 2 diabetes mellitus]. 2009 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:19848202
Gao L et al. [Of berberine and puerarin on dexamethasone-induced insulin resistance in porcine ovarian thecal cells]. 2009 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:19852296
Han J et al. [Inhibitory effects of puerarin on invasion and metastasis of oophoroma cells HO-8910]. 2009 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:19852298
Li DY et al. [Clinical significance of matrix metalloproteinase-9 and tissue factors secreted by cultured monocyte-derived macrophage of patients with coronary heart disease in vitro and the intervenient effect of puerarin on them]. 2007 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:17879530