| MeSH term | MeSH ID | Detail |
|---|---|---|
| Urinary Incontinence | D014549 | 4 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Alcohol-Related Disorders | D019973 | 3 associated lipids |
SCHEMBL105486
Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with SCHEMBL105486?
SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with SCHEMBL105486
PubChem Associated disorders and diseases
What pathways are associated with SCHEMBL105486
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with SCHEMBL105486?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with SCHEMBL105486?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with SCHEMBL105486?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with SCHEMBL105486?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with SCHEMBL105486?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with SCHEMBL105486
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dong K et al. | [Endothelium-independent vasorelaxant effect of puerarin on rat thoracic aorta]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15631089 |
| Chauhan SK et al. | Determination of puerarin from pueraria tuberosa dc by HPLC. | 2004 | Anc Sci Life | pmid:22557128 |
| Chueh FS et al. | Puerarin acts through brain serotonergic mechanisms to induce thermal effects. | 2004 | J. Pharmacol. Sci. | pmid:15599109 |
| Song CY and Bi HM | [Effects of puerarin on plasma membrane GLUT4 content in skeletal muscle from insulin-resistant Sprague-Dawley rats under insulin stimulation]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15719689 |
| Guo XG et al. | [Effect of puerarin on L-type calcium channel in isolated rat ventricular myocytes]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15706853 |
| Han J et al. | [Effect of puerarin and daidzein on proliferating vascular smooth muscle cells]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15706898 |
| Li D et al. | In vitro enzymatic modification of puerarin to puerarin glycosides by maltogenic amylase. | 2004 | Carbohydr. Res. | pmid:15542087 |
| He X et al. | Purification of the isoflavonoid puerarin by adsorption chromatography on cross-linked 12% agarose. | 2004 | J Chromatogr A | pmid:15584227 |
| Meng F et al. | [Inhibitory effect of quercetin, rutin and puerarin on HDL oxidation induced by Cu2+]. | 2004 | Sichuan Da Xue Xue Bao Yi Xue Ban | pmid:15573768 |
| Dong K et al. | Endothelium-independent vasorelaxant effect of puerarin on rat thoracic aorta. | 2004 | Conf Proc IEEE Eng Med Biol Soc | pmid:17271112 |