| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alcohol-Related Disorders | D019973 | 3 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Urinary Incontinence | D014549 | 4 associated lipids |
| Hepatitis, Alcoholic | D006519 | 5 associated lipids |
| Dyspepsia | D004415 | 5 associated lipids |
| Hypertension, Renovascular | D006978 | 10 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Glucose Intolerance | D018149 | 13 associated lipids |
| Angina, Unstable | D000789 | 14 associated lipids |
| Brain Infarction | D020520 | 17 associated lipids |
SCHEMBL105486
Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with SCHEMBL105486?
SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with SCHEMBL105486
PubChem Associated disorders and diseases
What pathways are associated with SCHEMBL105486
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with SCHEMBL105486?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with SCHEMBL105486?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with SCHEMBL105486?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with SCHEMBL105486?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with SCHEMBL105486?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with SCHEMBL105486
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen WC et al. | Mediation of beta-endorphin by the isoflavone puerarin to lower plasma glucose in streptozotocin-induced diabetic rats. | 2004 | Planta Med. | pmid:14994187 |
| Wang B et al. | [Clinical analysis of 5 cases with acute intravascular hemolysis caused by puerarin]. | 2004 | Beijing Da Xue Xue Bao | pmid:14970887 |
| Zhang FR et al. | [Effects of puerarin on number and activity of endothelial progenitor cells from peripheral blood]. | 2004 | Zhongguo Zhong Yao Za Zhi | pmid:15506293 |
| Zhang Q et al. | Flow injection-chemiluminescence determination of puerarin in pharmaceutical preparations. | 2004 | J Pharm Biomed Anal | pmid:15522534 |
| Prasain JK et al. | Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. | 2004 | J. Agric. Food Chem. | pmid:15186086 |
| Sang HF et al. | Effect of puerarin on neural function and histopathological damages after transient spinal cord ischemia in rabbits. | 2004 | Chin. J. Traumatol. | pmid:15294110 |
| Benlhabib E et al. | Effects of purified puerarin on voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. | 2004 | J Med Food | pmid:15298765 |
| Hao LN et al. | [Peroxynitrite-induced formation of diabetic cataract and its prevention by puerarin in rat]. | 2004 | Zhonghua Yan Ke Za Zhi | pmid:15312625 |
| Derda M et al. | [Amebicidal plants extracts]. | 2004 | Wiad Parazytol | pmid:16862806 |
| Dong K et al. | Endothelium-independent vasorelaxant effect of puerarin on rat thoracic aorta. | 2004 | Conf Proc IEEE Eng Med Biol Soc | pmid:17271112 |