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Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. |
2012 |
J Drug Deliv |
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Puerarin protects the rat liver against oxidative stress-mediated DNA damage and apoptosis induced by lead. |
2012 |
Exp. Toxicol. Pathol. |
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Fan R et al. |
Ethnopharmacokinetic- and activity-guided isolation of a new antidepressive compound from fructus aurantii found in the traditional chinese medicine chaihu-shugan-san: a new approach and its application. |
2012 |
Evid Based Complement Alternat Med |
pmid:22454671
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The isoflavone puerarin reduces alcohol intake in heavy drinkers: a pilot study. |
2012 |
Drug Alcohol Depend |
pmid:22578529
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Kim J et al. |
Puerarin inhibits the retinal pericyte apoptosis induced by advanced glycation end products in vitro and in vivo by inhibiting NADPH oxidase-related oxidative stress. |
2012 |
Free Radic. Biol. Med. |
pmid:22609359
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Luo J et al. |
Molecularly imprinted layer-coated monodisperse spherical silica microparticles toward affinity-enrichment of isoflavonoid glycosides from Radix puerariae. |
2012 |
Analyst |
pmid:22553769
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Involvement of abscisic acid in ozone-induced puerarin production of Pueraria thomsnii Benth. suspension cell cultures. |
2012 |
Plant Cell Rep. |
pmid:21947422
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Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death. |
2012 |
Neurochem. Int. |
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Zheng GM et al. |
Puerarin suppresses production of nitric oxide and inducible nitric oxide synthase in lipopolysaccharide-induced N9 microglial cells through regulating MAPK phosphorylation, O-GlcNAcylation and NF-κB translocation. |
2012 |
Int. J. Oncol. |
pmid:22246431
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Lin F et al. |
Protective effect of Puerarin on β-amyloid-induced neurotoxicity in rat hippocampal neurons. |
2012 |
Arzneimittelforschung |
pmid:22278629
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Tang XL et al. |
Dynamic oxidative stress and DNA damage induced by oestrogen deficiency and protective effects of puerarin and 17β-oestradiol in ovariectomized rats. |
2012 |
Basic Clin. Pharmacol. Toxicol. |
pmid:22333267
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Huang F et al. |
Puerarin attenuates endothelial insulin resistance through inhibition of inflammatory response in an IKKβ/IRS-1-dependent manner. |
2012 |
Biochimie |
pmid:22314193
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Tiyasatkulkovit W et al. |
Upregulation of osteoblastic differentiation marker mRNA expression in osteoblast-like UMR106 cells by puerarin and phytoestrogens from Pueraria mirifica. |
2012 |
Phytomedicine |
pmid:22951392
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Coghlan ML et al. |
Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns. |
2012 |
PLoS Genet. |
pmid:22511890
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Wang PP et al. |
Puerarin stimulates osteoblasts differentiation and bone formation through estrogen receptor, p38 MAPK, and Wnt/β-catenin pathways. |
2012 |
J Asian Nat Prod Res |
pmid:22917468
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Saha P et al. |
Puerarin, a selective oestrogen receptor modulator, disrupts pregnancy in rats at pre-implantation stage. |
2012 |
Reproduction |
pmid:22919047
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Fan JP et al. |
Optimization of ionic liquid based ultrasonic assisted extraction of puerarin from Radix Puerariae Lobatae by response surface methodology. |
2012 |
Food Chem |
pmid:22980805
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Liu CM et al. |
Puerarin protects rat kidney from lead-induced apoptosis by modulating the PI3K/Akt/eNOS pathway. |
2012 |
Toxicol. Appl. Pharmacol. |
pmid:22172631
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Zeng A et al. |
Simultaneous analysis and retention behavior of major isoflavonoids in Radix Puerariae lobatae and Radix Puerariae thomsonii by high performance liquid chromatography with cyclodextrins as a mobile phase modifier. |
2012 |
Anal. Chim. Acta |
pmid:22177078
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[Puerarin inhibits DNA damage of HaCaT cells induced by UVB via ceramide pathway]. |
2012 |
Yao Xue Xue Bao |
pmid:22812004
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Enzymatic synthesis of puerarin glucosides using Leuconostoc dextransucrase. |
2012 |
J. Microbiol. Biotechnol. |
pmid:22814496
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[Study on 3'-methoxy puerarin to dynamic changes of amino acids in rat brain ischemia-reperfusion]. |
2012 |
Zhongguo Zhong Yao Za Zhi |
pmid:22792810
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Puerarin inhibits caspase-3 expression in osteoblasts of diabetic rats. |
2012 |
Mol Med Rep |
pmid:22470138
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Acute effect of high-dose isoflavones from Pueraria lobata (Willd.) Ohwi on lipid and bone metabolism in ovariectomized mice. |
2012 |
Phytother Res |
pmid:22422661
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Zhang MY et al. |
In vitro and in vivo effects of puerarin on promotion of osteoblast bone formation. |
2012 |
Chin J Integr Med |
pmid:22457138
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Pang W et al. |
Effect of puerarin on the release of interleukin-8 in co-culture of human bronchial epithelial cells and neutrophils. |
2012 |
Chin J Integr Med |
pmid:22457139
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Zhao Y and Zhou Y |
Puerarin improve insulin resistance of adipocyte through activating Cb1 binding protein path. |
2012 |
Chin J Integr Med |
pmid:22457141
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Chen C et al. |
Puerarin induces mitochondria-dependent apoptosis in hypoxic human pulmonary arterial smooth muscle cells. |
2012 |
PLoS ONE |
pmid:22457823
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Hao LN et al. |
Puerarin decreases apoptosis of retinal pigment epithelial cells in diabetic rats by reducing peroxynitrite level and iNOS expression. |
2012 |
Sheng Li Xue Bao |
pmid:22513471
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Yao XJ et al. |
Puerarin exerts antipyretic effect on lipopolysaccharide-induced fever in rats involving inhibition of pyrogen production from macrophages. |
2012 |
J Ethnopharmacol |
pmid:22401764
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Yu N et al. |
The effects of sperminated pullulans on cornea permeability to puerarin and the toxicity. |
2012 |
J Ocul Pharmacol Ther |
pmid:22690870
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Wang R et al. |
[Protective effects of puerarin on 60Co-gamma-induced acute injury of sertoli cells of testis in mice]. |
2012 |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
pmid:22686089
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UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for puerarin metabolism in human liver microsomes. |
2012 |
Arch. Toxicol. |
pmid:22648071
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Osteoblast response to puerarin-loaded porous titanium surfaces: an in vitro study. |
2012 |
J Biomed Mater Res A |
pmid:22374837
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Zhang H et al. |
Insight into the structural deformations of beta-cyclodextrin caused by alcohol cosolvents and guest molecules. |
2012 |
J Phys Chem B |
pmid:22376204
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[Puerarin combined with avandia for diabetic nephropathy]. |
2012 |
Zhong Nan Da Xue Xue Bao Yi Xue Ban |
pmid:22349389
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Liu L et al. |
Determination of puerarin in pharmaceutical and biological samples by capillary zone electrophoresis with UV detection. |
2012 |
Talanta |
pmid:22365684
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Zhang Y et al. |
Characterization and evaluation of self-microemulsifying sustained-release pellet formulation of puerarin for oral delivery. |
2012 |
Int J Pharm |
pmid:22366381
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Deng L et al. |
[Effect of catalpol and puerarin freeze-dried powder on coagulability, hemorheology and no in rats with Qi-deficiency and blood-stasis syndrome]. |
2012 |
Zhongguo Zhong Yao Za Zhi |
pmid:22860464
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Liang X et al. |
[Intestinal absorption effect of Angelica dahurica extract on puerarin of puerariae Lobatae Radix]. |
2012 |
Zhongguo Zhong Yao Za Zhi |
pmid:22860465
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Zeng X et al. |
Enhanced adsorption of puerarin onto a novel hydrophilic and polar modified post-crosslinked resin from aqueous solution. |
2012 |
J Colloid Interface Sci |
pmid:22878002
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Puerarin exerted anti-osteoporotic action independent of estrogen receptor-mediated pathway. |
2012 |
J. Nutr. Sci. Vitaminol. |
pmid:22878391
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Zhang BS et al. |
[Cellular absorption of the active ingredients in different compatibilities of gegenqinlian decoction in human intestinal Caco-2 cells]. |
2012 |
Zhong Yao Cai |
pmid:23451503
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[Intestinal absorption of different combinations of active compounds from Gegenqinlian decoction by rat single pass intestinal perfusion in situ]. |
2012 |
Yao Xue Xue Bao |
pmid:23460978
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Physicochemical [corrected] properties of the inclusion complex of puerarin and glucosyl-β-cyclodextrin. |
2012 |
J. Agric. Food Chem. |
pmid:23215052
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[Determination of five components in Pueraria labta decoction with reference extraction method]. |
2012 |
Zhongguo Zhong Yao Za Zhi |
pmid:23234135
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Sun XY et al. |
[Optimal extraction of puerarin from Pueraria lobata based on central composite design and response surface methodology]. |
2012 |
Zhong Yao Cai |
pmid:23236837
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Chen YY et al. |
Puerarin protects human umbilical vein endothelial cells against high glucose-induced apoptosis by upregulating heme oxygenase-1 and inhibiting calpain activation. |
2012 |
Fundam Clin Pharmacol |
pmid:21352351
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Hu JJ et al. |
[Effect of pretreatment with puerarin on activation of LPS-induced RAW264. 7 cells]. |
2012 |
Zhongguo Zhong Yao Za Zhi |
pmid:23311164
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Liu XY et al. |
[Stability of PEGylated puerarin under different storage conditions]. |
2012 |
Zhongguo Zhong Yao Za Zhi |
pmid:23373208
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Prasain JK et al. |
The Chinese Pueraria root extract (Pueraria lobata) ameliorates impaired glucose and lipid metabolism in obese mice. |
2012 |
Phytomedicine |
pmid:23123226
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Chen R et al. |
Puerarin prevents isoprenaline-induced myocardial fibrosis in mice by reduction of myocardial TGF-β1 expression. |
2012 |
J. Nutr. Biochem. |
pmid:22079205
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Han JQ et al. |
[Effects of puerarin on the neurocyte apoptosis and p-Akt (Ser473) expressions in rats with cerebral ischemia/reperfusion injury]. |
2012 |
Zhongguo Zhong Xi Yi Jie He Za Zhi |
pmid:23173255
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Liang XL et al. |
Transport properties of puerarin and effect of Radix Angelicae Dahuricae extract on the transport of puerarin in Caco-2 cell model. |
2012 |
J Ethnopharmacol |
pmid:23085309
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Zhang Q et al. |
Puerarin protects differentiated PC12 cells from Hâ‚‚Oâ‚‚-induced apoptosis through the PI3K/Akt signalling pathway. |
2012 |
Cell Biol. Int. |
pmid:22126839
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Ford AP |
In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. |
2012 |
Purinergic Signal. |
pmid:22095157
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Xu C et al. |
Role of puerarin in the signalling of neuropathic pain mediated by P2X3 receptor of dorsal root ganglion neurons. |
2012 |
Brain Res. Bull. |
pmid:22044944
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Jin SE et al. |
Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots. |
2012 |
Arch. Pharm. Res. |
pmid:22644850
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Cheng W et al. |
Puerarin suppresses proliferation of endometriotic stromal cells partly via the MAPK signaling pathway induced by 17ß-estradiol-BSA. |
2012 |
PLoS ONE |
pmid:23029074
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Zhao X et al. |
Simultaneous determination of six isoflavonoids in rat plasma after administration of total flavonoid from Gegen by ultra-HPLC-MS/MS. |
2012 |
J Sep Sci |
pmid:22589159
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Sheu SY et al. |
Stimulatory effect of puerarin on bone formation through co-activation of nitric oxide and bone morphogenetic protein-2/mitogen-activated protein kinases pathways in mice. |
2012 |
Chin. Med. J. |
pmid:23075718
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Ho FM et al. |
Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. |
2012 |
J Ethnopharmacol |
pmid:22543166
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Gomuttapong S et al. |
Testing of the estrogenic activity and toxicity of Stephania venosa herb in ovariectomized rats. |
2012 |
Toxicol. Mech. Methods |
pmid:22394346
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Li Y et al. |
Comparative pharmacokinetics of prim-O-glucosylcimifugin and cimifugin by liquid chromatography-mass spectrometry after oral administration of Radix Saposhnikoviae extract, cimifugin monomer solution and prim-O-glucosylcimifugin monomer solution to rats. |
2012 |
Biomed. Chromatogr. |
pmid:22253022
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Song JX et al. |
Anti-Parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models? |
2012 |
J Ethnopharmacol |
pmid:22212501
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Deng Y et al. |
Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery. |
2012 |
J Ethnopharmacol |
pmid:22120017
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Yu L et al. |
Biotransformation of puerarin into puerarin-6″-O-phosphate by Bacillus cereus. |
2012 |
J. Ind. Microbiol. Biotechnol. |
pmid:21882014
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Wang X et al. |
Identification and assay of 3'-O-methyltaxifolin by UPLC-MS in rat plasma. |
2012 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:23217303
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Wen Y et al. |
Simultaneous determination of lidamycin enediyne chromophore (LDC) and its aromatized derivative (LDCA) using puerarin as internal standard in rat plasma by LC-MS/MS. |
2012 |
Biomed. Chromatogr. |
pmid:21830226
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Deng Y et al. |
[Effect of phenformin hydrochloride on pharmacokinetics of puerarin in rats]. |
2012 |
Zhongguo Zhong Yao Za Zhi |
pmid:23270242
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Luo J and Xu H |
Outcome measures of chinese herbal medicine for coronary heart disease: an overview of systematic reviews. |
2012 |
Evid Based Complement Alternat Med |
pmid:22606207
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Yan F et al. |
Effects of some antihypertensive drugs on the metabolism and pharmacokinetics of indapamide in rats. |
2012 |
J Pharm Pharm Sci |
pmid:22579001
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Wang J and Xiong X |
Current situation and perspectives of clinical study in integrative medicine in china. |
2012 |
Evid Based Complement Alternat Med |
pmid:22550539
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Jiang H et al. |
Natural product nitric oxide chemistry: new activity of old medicines. |
2012 |
Evid Based Complement Alternat Med |
pmid:22548122
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Qiu Y et al. |
Traditional chinese herbal products for coronary heart disease: an overview of cochrane reviews. |
2012 |
Evid Based Complement Alternat Med |
pmid:22536282
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Yang R et al. |
Determination of puerarin in biological samples and its application to a pharmacokinetic study by flow-injection chemiluminescence. |
2011 Sep-Oct |
Luminescence |
pmid:21547999
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Zhao C et al. |
Rapid simultaneous determination of major isoflavones of Pueraria lobata and discriminative analysis of its geographical origins by principal component analysis. |
2011 Nov-Dec |
Phytochem Anal |
pmid:21495105
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Chauhan NS et al. |
Spectrofluorimetric estimation of puerarin in Pueraria tuberosa. |
2011 May-Jun |
Acta Pol Pharm |
pmid:21648202
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Qin P et al. |
Characterization and selectivity studies of molecular imprinted membranes of Puerarin using scanning electron microscopy. |
2011 Jan-Feb |
Scanning |
pmid:21246571
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Liu IM and Cheng JT |
Mediation of Endogenous β-Endorphin in the Plasma Glucose-Lowering Action of Herbal Products Observed in Type 1-Like Diabetic Rats. |
2011 |
Evid Based Complement Alternat Med |
pmid:19095661
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Yu A et al. |
Formulation optimization and bioavailability after oral and nasal administration in rabbits of puerarin-loaded microemulsion. |
2011 |
J Pharm Sci |
pmid:20862776
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Zhang H et al. |
Puerarin protects Alzheimer's disease neuronal cybrids from oxidant-stress induced apoptosis by inhibiting pro-death signaling pathways. |
2011 |
Exp. Gerontol. |
pmid:20933077
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Wang G et al. |
Implication of the c-Jun-NH2-terminal kinase pathway in the neuroprotective effect of puerarin against 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in PC-12 cells. |
2011 |
Neurosci. Lett. |
pmid:20934486
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Tian F et al. |
The optimal therapeutic timing and mechanism of puerarin treatment of spinal cord ischemia-reperfusion injury in rats. |
2011 |
J Ethnopharmacol |
pmid:21296138
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He X et al. |
A genomic approach to isoflavone biosynthesis in kudzu (Pueraria lobata). |
2011 |
Planta |
pmid:21221632
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Zhang L et al. |
Intestinal absorbability of three Radix Puerariae isoflavones including daidzein, daidzin and puerarin. |
2011 |
Chin Med |
pmid:22108408
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Cui SQ |
[Effect of puerarin in myocardial protection in rats with acute and chronic alcoholism]. |
2011 |
Nan Fang Yi Ke Da Xue Xue Bao |
pmid:22200707
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Zhang XP et al. |
Protective effects of Ligustrazine, Kakonein and Panax Notoginsenoside on the small intestine and immune organs of rats with severe acute pancreatitis. |
2011 |
HBPD INT |
pmid:22146628
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Zhang H et al. |
Puerarin: a novel antagonist to inward rectifier potassium channel (IK1). |
2011 |
Mol. Cell. Biochem. |
pmid:21327545
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Yao C et al. |
[Ocular pharmacokinetics of puerarin in anesthetic rabbits by microdialysis]. |
2011 |
Zhongguo Zhong Yao Za Zhi |
pmid:22097338
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Zhang X et al. |
[Puerarin induced apoptosis of pulmonary artery smooth muscle cell by mitochondrial pathway]. |
2011 |
Zhongguo Zhong Yao Za Zhi |
pmid:22097342
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Chen X et al. |
[Study on pharmacokinetics of puerarin in rats following different methods of administration of Tongqiao Sanyu prescription]. |
2011 |
Zhongguo Zhong Yao Za Zhi |
pmid:22121800
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Hsiang SW et al. |
Puerarin accelerates peripheral nerve regeneration. |
2011 |
Am. J. Chin. Med. |
pmid:22083991
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Chen L et al. |
[Flavonoids of puerarin versus tanshinone II A for ischemic stroke: a randomized controlled trial]. |
2011 |
Zhong Xi Yi Jie He Xue Bao |
pmid:22088587
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Lipovac M et al. |
Effect of Red Clover Isoflavones over Skin, Appendages, and Mucosal Status in Postmenopausal Women. |
2011 |
Obstet Gynecol Int |
pmid:22135679
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Li X et al. |
Puerarin alleviates burn-related procedural pain mediated by P2X(3) receptors. |
2011 |
Purinergic Signal. |
pmid:21833698
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Kalani M and Yunus R |
Application of supercritical antisolvent method in drug encapsulation: a review. |
2011 |
Int J Nanomedicine |
pmid:21796245
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Pan SY et al. |
New perspectives on chinese herbal medicine (zhong-yao) research and development. |
2011 |
Evid Based Complement Alternat Med |
pmid:21785622
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Kim Y et al. |
Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat. |
2011 |
PLoS ONE |
pmid:21765914
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Su SY and Hsieh CL |
Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia. |
2011 |
Chin Med |
pmid:21740583
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