| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
SCHEMBL105486
Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with SCHEMBL105486?
SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with SCHEMBL105486
PubChem Associated disorders and diseases
What pathways are associated with SCHEMBL105486
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with SCHEMBL105486?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with SCHEMBL105486?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with SCHEMBL105486?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with SCHEMBL105486?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with SCHEMBL105486?
Knock-out
Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with SCHEMBL105486
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wu P et al. | [Study on effect of Puerarin on nitric oxide system in rats' tissue and its mechanism]. | 2001 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12577337 |
| Luo ZR and Zheng B | [Effect of Puerarin on platelet activating factors CD63 and CD62P, plasminogen activator inhibitor and C-reactive protein in patients with unstable angia pectoris]. | 2001 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12577374 |
| Xu XH and Zhang ZG | [Effect of puerarin on learning-memory behavior and synaptic structure of hippocampus in the aging mice induced by D-galactose]. | 2002 | Yao Xue Xue Bao | pmid:12579889 |
| Shi WG et al. | [Study on interventing effect of puerarin on insulin resistance in patients with coronary heart disease]. | 2002 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12585165 |
| Overstreet DH et al. | Herbal remedies for alcoholism: promises and possible pitfalls. | 2003 | Alcohol. Clin. Exp. Res. | pmid:12605067 |
| Bae HS et al. | Hepatoprotective activity of reduohanxiao-tang (yuldahanso-tang) is related to the inhibition of beta-glucuronidase. | 2003 | Am. J. Chin. Med. | pmid:12723760 |
| Zhu ZT et al. | [Inhibitive effect of puerarin on increased NO production by neonatal cardiomyocytes during hypoxia/reoxygenation injury]. | 2001 | Zhongguo Zhong Yao Za Zhi | pmid:12776339 |
| Huang YF et al. | [Determination of puerarin in xinmaitong oral liquid by HPLC]. | 2001 | Zhongguo Zhong Yao Za Zhi | pmid:12776346 |
| Qi BL and Qi BM | [Effect of the purariae-isofiavones on estrogen level in normal and ovariectomized rats]. | 2002 | Zhongguo Zhong Yao Za Zhi | pmid:12776591 |
| Shi RL and Zhang JJ | [Protective effect of puerarin on vascular endothelial cell apoptosis induced by chemical hypoxia in vitro]. | 2003 | Yao Xue Xue Bao | pmid:12778743 |