SCHEMBL62444

SCHEMBL62444 is a lipid of Polyketides (PK) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 584 references associated with SCHEMBL62444 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for SCHEMBL62444

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with SCHEMBL62444

MeSH term MeSH ID Detail
Weight Gain D015430 101 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 2

NCBI Entrez Crosslinks

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Authors Title Published Journal PubMed Link
Russo M et al. Phytochemicals in cancer prevention and therapy: truth or dare? 2010 Toxins (Basel) pmid:22069598
Stump DG et al. Developmental neurotoxicity study of dietary bisphenol A in Sprague-Dawley rats. 2010 Toxicol. Sci. pmid:20164145
Muñoz Y et al. Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets. 2009 Thromb. Res. pmid:18786699
Tanaka M et al. Isoflavone supplements stimulated the production of serum equol and decreased the serum dihydrotestosterone levels in healthy male volunteers. 2009 Prostate Cancer Prostatic Dis. pmid:19597532
Lai JN et al. Increased risk for invasive breast cancer associated with hormonal therapy: a nation-wide random sample of 65,723 women followed from 1997 to 2008. 2011 PLoS ONE pmid:21998640
Zhang HH et al. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway. 2009 PLoS ONE pmid:19593385
Yamaki K et al. Effects of naturally occurring isoflavones on prostaglandin E2 production. 2002 Planta Med. pmid:11859455
Lozovaya VV et al. Isoflavonoid accumulation in soybean hairy roots upon treatment with Fusarium solani. 2004 Jul-Aug Plant Physiol. Biochem. pmid:15331097
Hidaka S et al. Evaluation of a soybean product fujiflavone P40 as an antiosteoporotic agent in rats. 2003 Phytother Res pmid:12601671
Albert A et al. Efficacy and safety of a phytoestrogen preparation derived from Glycine max (L.) Merr in climacteric symptomatology: a multicentric, open, prospective and non-randomized trial. 2002 Phytomedicine pmid:11995954
Lapcík O et al. Isoflavonoids in the Rutaceae family: 1. Fortunella obovata, Murraya paniculata and four Citrus species. 2004 Sep-Oct Phytochem Anal pmid:15508833
Caligiani A et al. 1H NMR fingerprinting of soybean extracts, with emphasis on identification and quantification of isoflavones. 2010 Nutrients pmid:22254020
Shim JY et al. Effects of soybean isoflavone extract on the plasma lipid profiles and antioxidant enzyme activity in streptozotocin-induced diabetic rats. 2008 Nutr Res Pract pmid:20016722
Messina MJ and Wood CE Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary. 2008 Nutr J pmid:18522734
Sepehr E et al. Bioavailability of soy isoflavones in rats Part I: application of accurate methodology for studying the effects of gender and source of isoflavones. 2007 Mol Nutr Food Res pmid:17576640
Sepehr E et al. Effect of glycosidation of isoflavones on their bioavailability and pharmacokinetics in aged male rats. 2009 Mol Nutr Food Res pmid:19437481
Cavallini DC et al. Effects of isoflavone-supplemented soy yogurt on lipid parameters and atherosclerosis development in hypercholesterolemic rabbits: a randomized double-blind study. 2009 Lipids Health Dis pmid:19814806
Cavallini DC et al. Effects of probiotic bacteria, isoflavones and simvastatin on lipid profile and atherosclerosis in cholesterol-fed rabbits: a randomized double-blind study. 2009 Lipids Health Dis pmid:19128464
Chun J et al. Hydrolysis of isoflavone glucosides in soymilk fermented with single or mixed cultures of Lactobacillus paraplantarum KM, Weissella sp. 33, and Enterococcus faecium 35 isolated from humans. 2008 J. Microbiol. Biotechnol. pmid:18388479
Chun J et al. Conversion of isoflavone glucosides to aglycones in soymilk by fermentation with lactic acid bacteria. 2007 J. Food Sci. pmid:17995840
Liu L et al. Screening and identification of BSA bound ligands from Puerariae lobata flower by BSA functionalized Fe₃O₄ magnetic nanoparticles coupled with HPLC-MS/MS. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22305973
Baranowska I et al. UHPLC method for the simultaneous determination of β-blockers, isoflavones and their metabolites in human urine. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21345747
Huang RY and Chou CC Stability of isoflavone isomers in steamed black soybeans and black soybean koji stored under different conditions. 2009 J. Agric. Food Chem. pmid:19256558
Tsai HS et al. Solvent effects on extraction and HPLC analysis of soybean isoflavones and variations of isoflavone compositions as affected by crop season. 2007 J. Agric. Food Chem. pmid:17708647
Marotti I et al. Biotransformation of common bean (Phaseolus vulgaris L.) flavonoid glycosides by bifidobacterium species from human intestinal origin. 2007 J. Agric. Food Chem. pmid:17439230
Lee IH and Chou CC Distribution profiles of isoflavone isomers in black bean kojis prepared with various filamentous fungi. 2006 J. Agric. Food Chem. pmid:16478253
Klejdus B et al. Evaluation of isoflavone aglycon and glycoside distribution in soy plants and soybeans by fast column high-performance liquid chromatography coupled with a diode-array detector. 2005 J. Agric. Food Chem. pmid:16028964
Xu Z et al. Stabilities of daidzin, glycitin, genistin, and generation of derivatives during heating. 2002 J. Agric. Food Chem. pmid:12452666
Duke SO et al. Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean. 2003 J. Agric. Food Chem. pmid:12502430
Roland WS et al. Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. 2011 J. Agric. Food Chem. pmid:21942422
Kim YS et al. Characterization of a GH3 family β-glucosidase from Dictyoglomus turgidum and its application to the hydrolysis of isoflavone glycosides in spent coffee grounds. 2011 J. Agric. Food Chem. pmid:21919440
Yeom SJ et al. Hydrolysis of isoflavone glycosides by a thermostable β-glucosidase from Pyrococcus furiosus. 2012 J. Agric. Food Chem. pmid:22251001
Pyo YH and Seong KS Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet. 2009 J. Agric. Food Chem. pmid:19697921
Lee SJ et al. Comparison of isoflavone concentrations in soybean (Glycine max (L.) Merrill) sprouts grown under two different light conditions. 2007 J. Agric. Food Chem. pmid:17941689
Zhang B et al. Influence of the application of three different elicitors on soybean plants on the concentrations of several isoflavones in soybean seeds. 2006 J. Agric. Food Chem. pmid:16848544
Wiseman H et al. Isoflavone aglycon and glucoconjugate content of high- and low-soy U.K. foods used in nutritional studies. 2002 J. Agric. Food Chem. pmid:11879011
Matulka RA et al. Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient. 2009 J Toxicol pmid:20107584
Micke GA et al. Method development and validation for isoflavones in soy germ pharmaceutical capsules using micellar electrokinetic chromatography. 2006 J Pharm Biomed Anal pmid:16631335
Pandey A et al. Pharmacological screening of Coriandrum sativum Linn. for hepatoprotective activity. 2011 J Pharm Bioallied Sci pmid:21966166
Bawa S The significance of soy protein and soy bioactive compounds in the prophylaxis and treatment of osteoporosis. 2010 J Osteoporos pmid:20981338
Saldanha SN and Tollefsbol TO The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes. 2012 J Oncol pmid:22187555
Alissa EM and Ferns GA Functional foods and nutraceuticals in the primary prevention of cardiovascular diseases. 2012 J Nutr Metab pmid:22570771
Gourineni VP et al. Combinational Effects of Prebiotics and Soybean against Azoxymethane-Induced Colon Cancer In Vivo. 2011 J Nutr Metab pmid:21961059
Ablajan K A study of characteristic fragmentation of isoflavonoids by using negative ion ESI-MSn. 2011 J Mass Spectrom pmid:21182215
Quan J et al. Effect of Soybean Hypocotyl Extract on Lipid Peroxidation in GK Rats. 2009 J Clin Biochem Nutr pmid:19430608
Klejdus B et al. Determination of isoflavones in soy bits by fast column high-performance liquid chromatography coupled with UV-visible diode-array detection. 2005 J Chromatogr A pmid:16114238
Klejdus B et al. Ultrahigh-pressure liquid chromatography of isoflavones and phenolic acids on different stationary phases. 2008 J Chromatogr A pmid:18501366
Chen LJ et al. Quantitative determination and structural characterization of isoflavones in nutrition supplements by liquid chromatography-mass spectrometry. 2005 J Chromatogr A pmid:16038195
Yang F et al. Separation and purification of isoflavones from a crude soybean extract by high-speed counter-current chromatography. 2001 J Chromatogr A pmid:11587334
Rostagno MA et al. Ultrasound-assisted extraction of soy isoflavones. 2003 J Chromatogr A pmid:14521308
Stockwell PB Abstracts of papers presented at the 2007 pittsburgh conference. 2007 J Autom Methods Manag Chem pmid:18528514
Miadoková E Isoflavonoids - an overview of their biological activities and potential health benefits. 2009 Interdiscip Toxicol pmid:21217857
Valachovicova T et al. Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways. 2004 Int. J. Oncol. pmid:15492830
Otieno DO et al. Isoflavone phytoestrogen degradation in fermented soymilk with selected beta-glucosidase producing L. acidophilus strains during storage at different temperatures. 2007 Int. J. Food Microbiol. pmid:17174431
Huang CC et al. Anti-photoaging effects of soy isoflavone extract (aglycone and acetylglucoside form) from soybean cake. 2010 Int J Mol Sci pmid:21614173
da Graça R Campos M and Matos MP Bioactivity of isoflavones: assessment through a theoretical model as a way to obtain a "Theoretical Efficacy Related to Estradiol (TERE)". 2010 Int J Mol Sci pmid:20386649
Kang KA et al. Inhibitory effects of glycitein on hydrogen peroxide induced cell damage by scavenging reactive oxygen species and inhibiting c-Jun N-terminal kinase. 2007 Free Radic. Res. pmid:17516245
Daly KT et al. Enhanced estrogenic responses and sensitivity to azoxymethane following dietary soy isoflavone supplementation in older female rats. 2007 Food Chem. Toxicol. pmid:17157426
Toro-Funes N et al. Fast simultaneous determination of free and conjugated isoflavones in soy milk by UHPLC-UV. 2012 Food Chem pmid:22980879
Qu LP et al. Isolation of six isoflavones from Semen sojae praeparatum by preparative HPLC. 2007 Fitoterapia pmid:17343991
Hsu A et al. Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells. 2010 Exp. Biol. Med. (Maywood) pmid:20404023
Kamiya T et al. The crude extract from puerariae flower exerts antiobesity and antifatty liver effects in high-fat diet-induced obese mice. 2012 Evid Based Complement Alternat Med pmid:22685484
Barrett JR The science of soy: what do we really know? 2006 Environ. Health Perspect. pmid:16759972
Chanteranne B et al. Food matrix and isoflavones bioavailability in early post menopausal women: a European clinical study. 2008 Clin Interv Aging pmid:19281063
Van Poppel H and Tombal B Chemoprevention of prostate cancer with nutrients and supplements. 2011 Cancer Manag Res pmid:21629831
Carrara VS et al. Effects of a methanolic fraction of soybean seeds on the transcriptional activity of peroxisome proliferator-activated receptors (PPAR). 2009 Braz. J. Med. Biol. Res. pmid:19448904
Thorp AA et al. Soya isoflavone supplementation enhances spatial working memory in men. 2009 Br. J. Nutr. pmid:19480732
Warri A et al. The role of early life genistein exposures in modifying breast cancer risk. 2008 Br. J. Cancer pmid:18392054
Kim BN et al. Characterization of a β-glucosidase from Sulfolobus solfataricus for isoflavone glycosides. 2012 Biotechnol. Lett. pmid:21898127
Yasuda S et al. Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection. 2004 Biosci. Biotechnol. Biochem. pmid:14745163
Lee SH et al. Enhanced bioavailability of soy isoflavones by complexation with beta-cyclodextrin in rats. 2007 Biosci. Biotechnol. Biochem. pmid:18071265
Uesugi T et al. Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin. 2001 Biol. Pharm. Bull. pmid:11305597
Lee KT et al. Tectorigenin, an isoflavone of Pueraria thunbergiana Benth., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells. 2001 Biol. Pharm. Bull. pmid:11642314
Choi I et al. Anti-obesity activities of fermented soygerm isoflavones by Bifidobacterium breve. 2007 Biofactors pmid:17673827
Park KY et al. Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana. 2002 Arch. Pharm. Res. pmid:12135104
Klejdus B et al. Rapid-resolution HPLC with spectrometric detection for the determination and identification of isoflavones in soy preparations and plant extracts. 2007 Anal Bioanal Chem pmid:17899029
Baranowska I and Magiera S Analysis of isoflavones and flavonoids in human urine by UHPLC. 2011 Anal Bioanal Chem pmid:20936271
Li XH et al. Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. 2005 Acta Pharmacol. Sin. pmid:16115375
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