Alpinumisoflavone

Alpinumisoflavone is a lipid of Polyketides (PK) class. The involved functions are known as inhibitors, Metabolic Inhibition, Hypoxia, Diastasis and Chemotaxis.

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Introduction

To understand associated biological information of Alpinumisoflavone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Alpinumisoflavone

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Alpinumisoflavone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Alpinumisoflavone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Alpinumisoflavone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

What genes are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Alpinumisoflavone

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Authors Title Published Journal PubMed Link
Li D et al. Alpinumisoflavone causes DNA damage in Colorectal Cancer Cells via blocking DNA repair mediated by RAD51. 2019 Life Sci. pmid:30448264
Qi CC et al. A new isoflavone from the roots of Ficus auriculata. 2018 Nat. Prod. Res. pmid:28521555
Yin J et al. Alpinumisoflavone rescues glucocorticoid-induced apoptosis of osteocytes via suppressing Nox2-dependent ROS generation. 2018 Pharmacol Rep pmid:29477034
Trinh BTD et al. High-Resolution Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Vietnamese Plants. 2017 Molecules pmid:28726759
Cong W et al. Alpinumisoflavone inhibits osteoclast differentiation and exerts anti-osteoporotic effect in ovariectomized mice. 2017 Biomed. Pharmacother. pmid:28651235
Wang Y et al. Alpinumisoflavone protects against glucocorticoid-induced osteoporosis through suppressing the apoptosis of osteoblastic and osteocytic cells. 2017 Biomed. Pharmacother. pmid:29203387
Zhang B et al. Alpinumisoflavone radiosensitizes esophageal squamous cell carcinoma through inducing apoptosis and cell cycle arrest. 2017 Biomed. Pharmacother. pmid:28843908
Mvondo MA et al. Alpinumisoflavone and abyssinone V 4'-methylether derived from Erythrina lysistemon (Fabaceae) promote HDL-cholesterol synthesis and prevent cholesterol gallstone formation in ovariectomized rats. 2015 J. Pharm. Pharmacol. pmid:25683903
Njamen D et al. Erythrina lysistemon-derived flavonoids account only in part for the plant's specific effects on rat uterus and vagina. 2015 J Basic Clin Physiol Pharmacol pmid:25153589
Kumar S et al. The anticancer potential of flavonoids isolated from the stem bark of Erythrina suberosa through induction of apoptosis and inhibition of STAT signaling pathway in human leukemia HL-60 cells. 2013 Chem. Biol. Interact. pmid:23850732