Alpinumisoflavone

Alpinumisoflavone is a lipid of Polyketides (PK) class. The involved functions are known as inhibitors, Metabolic Inhibition, Hypoxia, Diastasis and Chemotaxis.

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Introduction

To understand associated biological information of Alpinumisoflavone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Alpinumisoflavone

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Alpinumisoflavone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Alpinumisoflavone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Alpinumisoflavone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

What genes are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Alpinumisoflavone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Alpinumisoflavone

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Authors Title Published Journal PubMed Link
Li D et al. Alpinumisoflavone causes DNA damage in Colorectal Cancer Cells via blocking DNA repair mediated by RAD51. 2019 Life Sci. pmid:30448264
Qi CC et al. A new isoflavone from the roots of Ficus auriculata. 2018 Nat. Prod. Res. pmid:28521555
Yin J et al. Alpinumisoflavone rescues glucocorticoid-induced apoptosis of osteocytes via suppressing Nox2-dependent ROS generation. 2018 Pharmacol Rep pmid:29477034
Trinh BTD et al. High-Resolution Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Vietnamese Plants. 2017 Molecules pmid:28726759
Cong W et al. Alpinumisoflavone inhibits osteoclast differentiation and exerts anti-osteoporotic effect in ovariectomized mice. 2017 Biomed. Pharmacother. pmid:28651235
Wang Y et al. Alpinumisoflavone protects against glucocorticoid-induced osteoporosis through suppressing the apoptosis of osteoblastic and osteocytic cells. 2017 Biomed. Pharmacother. pmid:29203387
Zhang B et al. Alpinumisoflavone radiosensitizes esophageal squamous cell carcinoma through inducing apoptosis and cell cycle arrest. 2017 Biomed. Pharmacother. pmid:28843908
Mvondo MA et al. Alpinumisoflavone and abyssinone V 4'-methylether derived from Erythrina lysistemon (Fabaceae) promote HDL-cholesterol synthesis and prevent cholesterol gallstone formation in ovariectomized rats. 2015 J. Pharm. Pharmacol. pmid:25683903
Njamen D et al. Erythrina lysistemon-derived flavonoids account only in part for the plant's specific effects on rat uterus and vagina. 2015 J Basic Clin Physiol Pharmacol pmid:25153589
Kumar S et al. The anticancer potential of flavonoids isolated from the stem bark of Erythrina suberosa through induction of apoptosis and inhibition of STAT signaling pathway in human leukemia HL-60 cells. 2013 Chem. Biol. Interact. pmid:23850732
Mvondo MA et al. Effects of alpinumisoflavone and abyssinone V-4'-methyl ether derived from Erythrina lysistemon (Fabaceae) on the genital tract of ovariectomized female Wistar rat. 2012 Phytother Res pmid:22183714
Nana F et al. A new fatty aldol ester from the aerial part of Mimosa invisa (Mimosaceae). 2012 Nat. Prod. Res. pmid:22117104
Magne Nde CB et al. In vitro estrogenic activity of two major compounds from the stem bark of Erythrina lysistemon (Fabaceae). 2012 Eur. J. Pharmacol. pmid:22079771
Bankeu JJ et al. Isoflavone dimers and other bioactive constituents from the figs of Ficus mucuso. 2011 J. Nat. Prod. pmid:21619045
Chukwujekwu JC et al. Antibacterial activity of flavonoids from the stem bark of Erythrina caffra thunb. 2011 Phytother Res pmid:20623615
Namkoong S et al. Alpinumisoflavone induces apoptosis and suppresses extracellular signal-regulated kinases/mitogen activated protein kinase and nuclear factor-κB pathways in lung tumor cells. 2011 Biol. Pharm. Bull. pmid:21415528
Akiyama K et al. Lupin pyranoisoflavones inhibiting hyphal development in arbuscular mycorrhizal fungi. 2010 Phytochemistry pmid:20813384
Kuete V and Efferth T Cameroonian medicinal plants: pharmacology and derived natural products. 2010 Front Pharmacol pmid:21833168
Lee MS et al. Genistein-derivatives from Tetracera scandens stimulate glucose-uptake in L6 myotubes. 2009 Biol. Pharm. Bull. pmid:19252305
Djiogue S et al. Isoflavonoids from Erythrina poeppigiana: evaluation of their binding affinity for the estrogen receptor. 2009 J. Nat. Prod. pmid:19705860
Lee J et al. Prenylisoflavonoids from Erythrina senegalensis as novel HIV-1 protease inhibitors. 2009 Planta Med. pmid:19097000
Oh WK et al. Diacylglycerol acyltransferase-inhibitory compounds from Erythrina senegalensis. 2009 Arch. Pharm. Res. pmid:19183875
Liu Y et al. Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways. 2009 J. Biol. Chem. pmid:19091749
Togola A et al. Ethnopharmacological uses of Erythrina senegalensis: a comparison of three areas in Mali, and a link between traditional knowledge and modern biological science. 2008 J Ethnobiol Ethnomed pmid:18321374
Harrison JJ et al. Alpinumisoflavone. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21202104
Kuete V et al. Antimicrobial activity of the crude extracts and compounds from Ficus chlamydocarpa and Ficus cordata (Moraceae). 2008 J Ethnopharmacol pmid:18718518
Darbour N et al. Isoflavones from Ficus nymphaefolia. 2007 Nat. Prod. Res. pmid:17487619
Kingsford-Adaboh R et al. Invariom structure refinement, electrostatic potential and toxicity of 4-O-methylalpinumisoflavone, O,O-dimethylalpinumisoflavone and 5-O-methyl-4-O-(3-methylbut-2-en-1-yl)alpinumisoflavone. 2006 Acta Crystallogr., B pmid:16983165
Na M et al. Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii. 2006 J. Nat. Prod. pmid:17125223
Oh WK et al. Phospholipase Cgamma1 inhibitory activities of prenylated flavonoids isolated from Erythrina senegalensis. 2005 Planta Med. pmid:16142647
Han XH et al. Monoamine oxidase inhibitory constituents from the fruits of Cudrania tricuspidata. 2005 Arch. Pharm. Res. pmid:16392662
el-Masry S et al. Prenylated flavonoids of Erythrina lysistemon grown in Egypt. 2002 Phytochemistry pmid:12150799
Lyddiard JR et al. Antischistosomal bioactivity of isoflavonoids from Millettia thonningii (Leguminosae). 2002 J. Parasitol. pmid:12053958
Nkengfack AE et al. Cytotoxic isoflavones from Erythrina indica. 2001 Phytochemistry pmid:11730876
Tanaka H et al. Erythrinan alkaloids and isoflavonoids from Erythrina poeppigiana. 2001 Planta Med. pmid:11745029
Lyddiard JR and Whitfield PJ Inhibition of Site I mitochondrial electron transport by an extract of the seeds of Millettia thonningii: a potential mechanism for the plant's molluscicidal and schistosome larvicidal activity. 2001 J. Helminthol. pmid:11551316
Stewart M et al. Pyranoisoflavones from Rinorea welwitschii. 2000 Fitoterapia pmid:11449519
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