| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
Total
4
Tectorigenin
Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.
Cross Reference
Introduction
To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tectorigenin?
Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tectorigenin
PubChem Associated disorders and diseases
What pathways are associated with Tectorigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tectorigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tectorigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tectorigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Tectorigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tectorigenin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Tectorigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zeng L et al. | Suppression of human breast cancer cells by tectorigenin through downregulation of matrix metalloproteinases and MAPK signaling in vitro. | 2018 | Mol Med Rep | pmid:29359782 |
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| Lee SY et al. | Tectorigenin Promotes Osteoblast Differentiation and Bone Healing, but Suppresses Osteoclast Differentiation and Bone Resorption. | 2018 | Mol. Cells | pmid:29764006 |
| Applová L et al. | The isoflavonoid tectorigenin has better antiplatelet potential than acetylsalicylic acid. | 2017 | Phytomedicine | pmid:28991640 |
| Zhang Y et al. | Characterization and evaluation of a self-microemulsifying drug delivery system containing tectorigenin, an isoflavone with low aqueous solubility and poor permeability. | 2017 | Drug Deliv | pmid:28283000 |
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| Guo Y et al. | Tectorigenin inhibits osteosarcoma cell migration through downregulation of matrix metalloproteinases in vitro. | 2016 | Anticancer Drugs | pmid:26991068 |
| Shuai S et al. | Preparation, characterization and in vitro/vivo evaluation of tectorigenin solid dispersion with improved dissolution and bioavailability. | 2016 | Eur J Drug Metab Pharmacokinet | pmid:25669445 |
| Zhang R et al. | Protective Effect of an Isoflavone, Tectorigenin, Against Oxidative Stress-induced Cell Death via Catalase Activation. | 2016 | J Cancer Prev | pmid:28053960 |
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| Li QY et al. | Tectorigenin regulates adipogenic differentiation and adipocytokines secretion via PPARγ and IKK/NF-κB signaling. | 2015 | Pharm Biol | pmid:25856699 |
| Amin A et al. | Tectorigenin ablates the inflammation-induced epithelial-mesenchymal transition in a co-culture model of human lung carcinoma. | 2015 | Pharmacol Rep | pmid:25712668 |
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| Gao XX et al. | The therapeutic effects of tectorigenin on chemically induced liver fibrosis in rats and an associated metabonomic investigation. | 2012 | Arch. Pharm. Res. | pmid:22941492 |
| Han T et al. | In vitro evaluation of tectoridin, tectorigenin and tectorigenin sodium sulfonate on antioxidant properties. | 2012 | Food Chem. Toxicol. | pmid:22079309 |
| Yang YI et al. | Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFκB pathway. | 2012 | Carcinogenesis | pmid:23027625 |
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| Lee KT et al. | Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. | 2000 | Arch. Pharm. Res. | pmid:11059824 |
| Kim YP et al. | Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages. | 1999 | Biochim. Biophys. Acta | pmid:10366782 |
| Bae EA et al. | Metabolism of 6"-O-xylosyltectoridin and tectoridin by human intestinal bacteria and their hypoglycemic and in vitro cytotoxic activities. | 1999 | Biol. Pharm. Bull. | pmid:10746163 |
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