Tectorigenin

Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.

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Introduction

To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tectorigenin?

Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tectorigenin

MeSH term MeSH ID Detail
Neoplasms, Germ Cell and Embryonal D009373 4 associated lipids
Hyperglycemia D006943 21 associated lipids
Atherosclerosis D050197 85 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with Tectorigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tectorigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tectorigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tectorigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tectorigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tectorigenin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Tectorigenin

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Authors Title Published Journal PubMed Link
Thelen P et al. [Pharmacological potential of phytoestrogens in the treatment of prostate cancer]. 2006 Urologe A pmid:16237540
McArdle BM et al. A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. 2006 J. Nat. Prod. pmid:16441060
Shin JE et al. Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. 2006 Biol. Pharm. Bull. pmid:16755017
Moon HI et al. Aldose reductase inhibitory effect by tectorigenin derivatives from Viola hondoensis. 2006 Bioorg. Med. Chem. pmid:16870454
Stettner M et al. The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment. 2007 Mol. Cancer Ther. pmid:17913855
Bebrevska L et al. Development and validation of an HPLC method for quality control of Pueraria lobata flower. 2007 Planta Med. pmid:18067064
Chen Y et al. Identification of metabolites of tectoridin in-vivo and in-vitro by liquid chromatography-tandem mass spectrometry. 2008 J. Pharm. Pharmacol. pmid:18498706
Fang R et al. Cytotoxic effects of compounds from Iris tectorum on human cancer cell lines. 2008 J Ethnopharmacol pmid:18508214
Li J et al. Quality evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by using high-performance liquid chromatography coupled with diode array detector and mass spectrometry. 2009 J Chromatogr A pmid:18550076
Zhang WD et al. Identification of the major metabolites of tectorigenin in rat bile by liquid chromatography combined with time-of-flight and ion trap tandem mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18668634