Tectorigenin

Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.

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Introduction

To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tectorigenin?

Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tectorigenin

MeSH term MeSH ID Detail
Neoplasms, Germ Cell and Embryonal D009373 4 associated lipids
Hyperglycemia D006943 21 associated lipids
Atherosclerosis D050197 85 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with Tectorigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tectorigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tectorigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tectorigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tectorigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tectorigenin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Tectorigenin

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Authors Title Published Journal PubMed Link
pmid:
Guo Y et al. Tectorigenin inhibits osteosarcoma cell migration through downregulation of matrix metalloproteinases in vitro. 2016 Anticancer Drugs pmid:26991068
Pan CH et al. Tectorigenin inhibits IFN-gamma/LPS-induced inflammatory responses in murine macrophage RAW 264.7 cells. 2008 Arch. Pharm. Res. pmid:19023541
Jung SH et al. Antioxidant activities of isoflavones from the rhizomes of Belamcanda chinensis on carbon tetrachloride-induced hepatic injury in rats. 2004 Arch. Pharm. Res. pmid:15022720
Gao XX et al. The therapeutic effects of tectorigenin on chemically induced liver fibrosis in rats and an associated metabonomic investigation. 2012 Arch. Pharm. Res. pmid:22941492
Park KY et al. Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana. 2002 Arch. Pharm. Res. pmid:12135104
Lee KT et al. Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. 2000 Arch. Pharm. Res. pmid:11059824
Kim C et al. Study of substance changes in flowers of Pueraria thunbergiana Benth. during storage. 2003 Arch. Pharm. Res. pmid:12723934
Jung SH et al. Isoflavonoids from the rhizomes of Belamcanda chinensis and their effects on aldose reductase and sorbitol accumulation in streptozotocin induced diabetic rat tissues. 2002 Arch. Pharm. Res. pmid:12135102
Kim YP et al. Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages. 1999 Biochim. Biophys. Acta pmid:10366782