| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
Total
4
Tectorigenin
Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.
Cross Reference
Introduction
To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tectorigenin?
Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tectorigenin
PubChem Associated disorders and diseases
What pathways are associated with Tectorigenin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tectorigenin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tectorigenin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tectorigenin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Tectorigenin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tectorigenin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Tectorigenin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Lee YS et al. | Preparative isolation and purification of seven isoflavones from Belamcanda chinensis. | Phytochem Anal | pmid:21465599 | |
| Liu H et al. | [Separation and identification of chemical compositions from cultivated Belamcanda chinensis]. | 1997 | Zhong Yao Cai | pmid:12572475 |
| Kim YP et al. | Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages. | 1999 | Biochim. Biophys. Acta | pmid:10366782 |
| Bae EA et al. | Metabolism of 6"-O-xylosyltectoridin and tectoridin by human intestinal bacteria and their hypoglycemic and in vitro cytotoxic activities. | 1999 | Biol. Pharm. Bull. | pmid:10746163 |
| Shin KH et al. | Inhibition of prostaglandin E2 production by the isoflavones tectorigenin and tectoridin isolated from the rhizomes of Belamcanda chinensis. | 1999 | Planta Med. | pmid:10630127 |
| Lee KT et al. | Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. | 2000 | Arch. Pharm. Res. | pmid:11059824 |
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| Yamaki K et al. | Effects of naturally occurring isoflavones on prostaglandin E2 production. | 2002 | Planta Med. | pmid:11859455 |
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| Jung SH et al. | Anti-angiogenic and anti-tumor activities of isoflavonoids from the rhizomes of Belamcanda chinensis. | 2003 | Planta Med. | pmid:12898416 |
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| Jung SH et al. | Antioxidant activities of isoflavones from the rhizomes of Belamcanda chinensis on carbon tetrachloride-induced hepatic injury in rats. | 2004 | Arch. Pharm. Res. | pmid:15022720 |
| Morrissey C et al. | Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro. | 2004 | J. Urol. | pmid:15538285 |
| Viana GS et al. | Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides. | 2004 | BMC Pharmacol. | pmid:15182373 |
| Jung DY et al. | Induction of growth hormone release by Pueraria thunbergiana BENTH. | 2004 | Horm. Metab. Res. | pmid:15002057 |
| Seidlová-Wuttke D et al. | Belamcanda chinensis and the thereof purified tectorigenin have selective estrogen receptor modulator activities. | 2004 | Phytomedicine | pmid:15330494 |
| Park EK et al. | Passive cutaneous anaphylaxis-inhibitory action of tectorigenin, a metabolite of tectoridin by intestinal microflora. | 2004 | Biol. Pharm. Bull. | pmid:15256747 |
| Lee HU et al. | Hepatoprotective effect of tectoridin and tectorigenin on tert-butyl hyperoxide-induced liver injury. | 2005 | J. Pharmacol. Sci. | pmid:15821336 |
| Monthakantirat O et al. | Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines. | 2005 | J. Nat. Prod. | pmid:15787436 |
| Kang KA et al. | Cytoprotective effect of tectorigenin, a metabolite formed by transformation of tectoridin by intestinal microflora, on oxidative stress induced by hydrogen peroxide. | 2005 | Eur. J. Pharmacol. | pmid:16102749 |
| Thelen P et al. | Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer. | 2005 | Carcinogenesis | pmid:15845653 |
| O'Toole SA et al. | Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays. | 2005 | Planta Med. | pmid:15931582 |
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| McArdle BM et al. | A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. | 2006 | J. Nat. Prod. | pmid:16441060 |
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| Shin JE et al. | Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. | 2006 | Biol. Pharm. Bull. | pmid:16755017 |
| Stettner M et al. | The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment. | 2007 | Mol. Cancer Ther. | pmid:17913855 |
| Bebrevska L et al. | Development and validation of an HPLC method for quality control of Pueraria lobata flower. | 2007 | Planta Med. | pmid:18067064 |
| Pan CH et al. | Tectorigenin inhibits IFN-gamma/LPS-induced inflammatory responses in murine macrophage RAW 264.7 cells. | 2008 | Arch. Pharm. Res. | pmid:19023541 |
| Hong J et al. | Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea. | 2008 | Inflamm Allergy Drug Targets | pmid:18782027 |
| Zhang WD et al. | Identification of the major metabolites of tectorigenin in rat bile by liquid chromatography combined with time-of-flight and ion trap tandem mass spectrometry. | 2008 | Rapid Commun. Mass Spectrom. | pmid:18668634 |
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| Fang R et al. | Cytotoxic effects of compounds from Iris tectorum on human cancer cell lines. | 2008 | J Ethnopharmacol | pmid:18508214 |
| Chen Y et al. | Identification of metabolites of tectoridin in-vivo and in-vitro by liquid chromatography-tandem mass spectrometry. | 2008 | J. Pharm. Pharmacol. | pmid:18498706 |
| Zhang WD et al. | Identification of key metabolites of tectorigenin in rat urine by HPLC-MS(n). | 2009 | Biomed. Chromatogr. | pmid:18850580 |
| Qiu QH et al. | [Studies on the isoflavonoids of Iris tectorum]. | 2009 | Zhong Yao Cai | pmid:20034214 |
| Farag SF et al. | New isoflavone glycosides from Iris spuria L. (Calizona) cultivated in Egypt. | 2009 | J Nat Med | pmid:18791667 |
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| Jiang Y et al. | Isolation and purification of isoflavonoids from Rhizoma Belamcandae by two-dimensional preparative high-performance liquid chromatography with column switch technology. | 2009 | Biomed. Chromatogr. | pmid:19382246 |
| Li J et al. | Quality evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by using high-performance liquid chromatography coupled with diode array detector and mass spectrometry. | 2009 | J Chromatogr A | pmid:18550076 |