MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.
To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tectorigenin
MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thelen P et al. | [Pharmacological potential of phytoestrogens in the treatment of prostate cancer]. | 2006 | Urologe A | pmid:16237540 |
McArdle BM et al. | A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. | 2006 | J. Nat. Prod. | pmid:16441060 |
Shin JE et al. | Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. | 2006 | Biol. Pharm. Bull. | pmid:16755017 |
Moon HI et al. | Aldose reductase inhibitory effect by tectorigenin derivatives from Viola hondoensis. | 2006 | Bioorg. Med. Chem. | pmid:16870454 |
Stettner M et al. | The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment. | 2007 | Mol. Cancer Ther. | pmid:17913855 |
Bebrevska L et al. | Development and validation of an HPLC method for quality control of Pueraria lobata flower. | 2007 | Planta Med. | pmid:18067064 |
Chen Y et al. | Identification of metabolites of tectoridin in-vivo and in-vitro by liquid chromatography-tandem mass spectrometry. | 2008 | J. Pharm. Pharmacol. | pmid:18498706 |
Fang R et al. | Cytotoxic effects of compounds from Iris tectorum on human cancer cell lines. | 2008 | J Ethnopharmacol | pmid:18508214 |
Li J et al. | Quality evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by using high-performance liquid chromatography coupled with diode array detector and mass spectrometry. | 2009 | J Chromatogr A | pmid:18550076 |
Zhang WD et al. | Identification of the major metabolites of tectorigenin in rat bile by liquid chromatography combined with time-of-flight and ion trap tandem mass spectrometry. | 2008 | Rapid Commun. Mass Spectrom. | pmid:18668634 |