Tectorigenin

Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.

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Introduction

To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tectorigenin?

Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tectorigenin

MeSH term MeSH ID Detail
Hyperglycemia D006943 21 associated lipids
Neoplasms, Germ Cell and Embryonal D009373 4 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Atherosclerosis D050197 85 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with Tectorigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tectorigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tectorigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tectorigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tectorigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tectorigenin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Tectorigenin

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Authors Title Published Journal PubMed Link
Shin JE et al. Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. 2006 Biol. Pharm. Bull. pmid:16755017
McArdle BM et al. A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. 2006 J. Nat. Prod. pmid:16441060
Thelen P et al. [Pharmacological potential of phytoestrogens in the treatment of prostate cancer]. 2006 Urologe A pmid:16237540
Kang KA et al. Cytoprotective effect of tectorigenin, a metabolite formed by transformation of tectoridin by intestinal microflora, on oxidative stress induced by hydrogen peroxide. 2005 Eur. J. Pharmacol. pmid:16102749
O'Toole SA et al. Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays. 2005 Planta Med. pmid:15931582
Thelen P et al. Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer. 2005 Carcinogenesis pmid:15845653
Lee HU et al. Hepatoprotective effect of tectoridin and tectorigenin on tert-butyl hyperoxide-induced liver injury. 2005 J. Pharmacol. Sci. pmid:15821336
Monthakantirat O et al. Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines. 2005 J. Nat. Prod. pmid:15787436
Morrissey C et al. Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro. 2004 J. Urol. pmid:15538285
Seidlová-Wuttke D et al. Belamcanda chinensis and the thereof purified tectorigenin have selective estrogen receptor modulator activities. 2004 Phytomedicine pmid:15330494