MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.
To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tectorigenin
MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shin JE et al. | Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. | 2006 | Biol. Pharm. Bull. | pmid:16755017 |
McArdle BM et al. | A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets. | 2006 | J. Nat. Prod. | pmid:16441060 |
Thelen P et al. | [Pharmacological potential of phytoestrogens in the treatment of prostate cancer]. | 2006 | Urologe A | pmid:16237540 |
Kang KA et al. | Cytoprotective effect of tectorigenin, a metabolite formed by transformation of tectoridin by intestinal microflora, on oxidative stress induced by hydrogen peroxide. | 2005 | Eur. J. Pharmacol. | pmid:16102749 |
O'Toole SA et al. | Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays. | 2005 | Planta Med. | pmid:15931582 |
Thelen P et al. | Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer. | 2005 | Carcinogenesis | pmid:15845653 |
Lee HU et al. | Hepatoprotective effect of tectoridin and tectorigenin on tert-butyl hyperoxide-induced liver injury. | 2005 | J. Pharmacol. Sci. | pmid:15821336 |
Monthakantirat O et al. | Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines. | 2005 | J. Nat. Prod. | pmid:15787436 |
Morrissey C et al. | Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro. | 2004 | J. Urol. | pmid:15538285 |
Seidlová-Wuttke D et al. | Belamcanda chinensis and the thereof purified tectorigenin have selective estrogen receptor modulator activities. | 2004 | Phytomedicine | pmid:15330494 |