Tectorigenin

Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.

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Introduction

To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tectorigenin?

Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tectorigenin

MeSH term MeSH ID Detail
Hyperglycemia D006943 21 associated lipids
Neoplasms, Germ Cell and Embryonal D009373 4 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Atherosclerosis D050197 85 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with Tectorigenin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tectorigenin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tectorigenin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tectorigenin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tectorigenin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tectorigenin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Tectorigenin

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Authors Title Published Journal PubMed Link
Lim MP et al. Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. 2011 Cell Death Dis pmid:21654828
Park JS et al. Antioxidant mechanism of isoflavone metabolites in hydrogen peroxide-stimulated rat primary astrocytes: critical role of hemeoxygenase-1 and NQO1 expression. 2011 J. Neurochem. pmid:21781119
Jiang CP et al. Pro-apoptotic effects of tectorigenin on human hepatocellular carcinoma HepG2 cells. 2012 World J. Gastroenterol. pmid:22553399
Gao XX et al. The therapeutic effects of tectorigenin on chemically induced liver fibrosis in rats and an associated metabonomic investigation. 2012 Arch. Pharm. Res. pmid:22941492
Han T et al. In vitro evaluation of tectoridin, tectorigenin and tectorigenin sodium sulfonate on antioxidant properties. 2012 Food Chem. Toxicol. pmid:22079309
Yang YI et al. Tectorigenin sensitizes paclitaxel-resistant human ovarian cancer cells through downregulation of the Akt and NFκB pathway. 2012 Carcinogenesis pmid:23027625
Jun HJ et al. Iristectorigenin B isolated from Belamcanda chinensis is a liver X receptor modulator that increases ABCA1 and ABCG1 expression in macrophage RAW 264.7 cells. 2012 Biotechnol. Lett. pmid:23011313
Liu L et al. Screening and identification of BSA bound ligands from Puerariae lobata flower by BSA functionalized Fe₃O₄ magnetic nanoparticles coupled with HPLC-MS/MS. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22305973
Kamiya T et al. The crude extract from puerariae flower exerts antiobesity and antifatty liver effects in high-fat diet-induced obese mice. 2012 Evid Based Complement Alternat Med pmid:22685484
Qu J et al. Pharmacokinetics of conjugated metabolites in rat plasma after oral administration of tectoridin. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22771104