29623-28-7

29623-28-7 is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1002 references associated with 29623-28-7 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for 29623-28-7

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 29623-28-7

MeSH term MeSH ID Detail
Adenomatous Polyps D018256 4 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Familial Mediterranean Fever D010505 12 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Thrombosis D013927 49 associated lipids
Arteriosclerosis D001161 86 associated lipids
Hypertension D006973 115 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 29623-28-7

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Authors Title Published Journal PubMed Link
Pomposiello SI et al. Linoleic acid induces relaxation and hyperpolarization of the pig coronary artery. 1998 Hypertension pmid:9461230
Metzger K et al. Lipoxygenase products in human saliva: patients with oral cancer compared to controls. 1995 Free Radic. Biol. Med. pmid:7744301
Guo L et al. Preferential formation of the hydroperoxide of linoleic acid in choline glycerophospholipids in human erythrocytes membrane during peroxidation with an azo initiator. 1995 Free Radic. Biol. Med. pmid:7628726
Coleman JD et al. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). 2007 Free Radic. Biol. Med. pmid:17382197
Elékés E et al. Suppression of endotoxin mitogenicity of spleen cells by lipoxygenase inhibitors and its reversal by 13-hydroxyoctadecadienoic acid. 1993 FEMS Immunol. Med. Microbiol. pmid:8472013
van de Velde MJ et al. The linoleic acid metabolite 13-HODE modulates degranulation of human polymorphonuclear leukocytes. 1995 FEBS Lett. pmid:7649276
Inouye S Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid. 1984 FEBS Lett. pmid:6430718
Grøn B et al. Distribution of monohydroxy fatty acids in specific human epidermal phospholipids. 1993 Exp. Dermatol. pmid:8156169
Henricks PA et al. 13-hydroxy-linoleic acid induces airway hyperreactivity to histamine in guinea-pigs. 1991 Eur. J. Pharmacol. pmid:1915571
Buckley TL et al. 13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin. 1992 Eur. J. Pharmacol. pmid:1330604
Sakashita T et al. Essential involvement of 12-lipoxygenase in regiospecific andstereospecific oxidation of low density lipoprotein by macrophages. 1999 Eur. J. Biochem. pmid:10504415
Chouinard S et al. Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation. 2006 Endocrinology pmid:16887906
Jude AR et al. 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. 2001 Drug Metab. Dispos. pmid:11302930
Imaizumi S et al. L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. 2010 Drug Metab Lett pmid:20642447
Li MY et al. Pioglitazone prevents smoking carcinogen-induced lung tumor development in mice. 2012 Curr Cancer Drug Targets pmid:22463586
Dauchy RT et al. Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids. 2007 Comp. Med. pmid:17803052
Klawitter J et al. Pravastatin Therapy and Biomarker Changes in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease. 2015 Clin J Am Soc Nephrol pmid:26224879
De Meyer GR et al. Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin-mediated responses in the rabbit carotid artery. 1991 Circ. Res. pmid:1645234
Liu W et al. Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios. 2010 Chem. Res. Toxicol. pmid:20423158
Schneider C et al. Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. 2004 Chem. Res. Toxicol. pmid:15257619
Jira W et al. Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients. 1998 Chem. Phys. Lipids pmid:9488997
Batna A et al. Lipid peroxidation in presence of ebselen. 1997 Chem. Phys. Lipids pmid:9275309
Jira W et al. Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. 1997 Chem. Phys. Lipids pmid:9219348
Manini P et al. Biomimetic nitration of the linoleic acid metabolite 13-hydroxyoctadecadienoic acid: isolation and spectral characterization of novel chain-rearranged epoxy nitro derivatives. 2008 Chem. Phys. Lipids pmid:18320610
Manini P et al. Free radical oxidation of coriolic acid (13-(S)-hydroxy-9Z,11E-octadecadienoic acid). 2005 Chem. Phys. Lipids pmid:15784234
Mani I et al. Upregulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: modulation by 13-(S)-hydroxyoctadecadienoic acid (13-HODE). 1998 Cell. Signal. pmid:9481490
Liu B et al. Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C. 1991 Cell Regul. pmid:1801923
Nagy L et al. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. 1998 Cell pmid:9568715
Kelavkar UP et al. Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. 2001 Carcinogenesis pmid:11698337
Blask DE et al. Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin. 2004 Carcinogenesis pmid:14754876
Wu J et al. 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer. 2003 Carcinogenesis pmid:12584173
Cimen I et al. 15-Lipoxygenase-1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT-116 and HT-29. 2009 Cancer Sci. pmid:19775287
Shureiqi I et al. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. 2000 Cancer Res. pmid:11156377
Grossi IM et al. Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid. 1989 Cancer Res. pmid:2492204
Shureiqi I et al. Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. 2001 Cancer Res. pmid:11406566
Müller K et al. Modulation of epidermal tumor development caused by targeted overexpression of epidermis-type 12S-lipoxygenase. 2002 Cancer Res. pmid:12183416
Sauer LA et al. 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. 1999 Cancer Res. pmid:10493526
Blask DE et al. Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. 1999 Cancer Res. pmid:10493527
Hsi LC et al. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. 2004 Cancer Res. pmid:15574791
Shureiqi I et al. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. 2005 Cancer Res. pmid:16357157
Sauer LA et al. Mechanism for the antitumor and anticachectic effects of n-3 fatty acids. 2000 Cancer Res. pmid:11016660
Shureiqi I et al. Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. 2010 Cancer Prev Res (Phila) pmid:20570882
Schneider C and Pozzi A Cyclooxygenases and lipoxygenases in cancer. 2011 Cancer Metastasis Rev. pmid:22002716
Dauchy RT et al. Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. 2004 Cancer Lett. pmid:15145516
Dauchy RT et al. Dim light during darkness stimulates tumor progression by enhancing tumor fatty acid uptake and metabolism. 1999 Cancer Lett. pmid:10529012
Silverman AL et al. Decreased levels of 13-hydroxyoctadecadienoic acid (13-HODE) dehydrogenase in neoplastic tissue of human colon biopsies. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8770467
Blask DE et al. Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. 2003 Breast Cancer Res. Treat. pmid:12846415
Camp RD and Fincham NJ Inhibition of ionophore-stimulated leukotriene B4 production in human leucocytes by monohydroxy fatty acids. 1985 Br. J. Pharmacol. pmid:2994785
Alsalem M et al. The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms. 2013 Br. J. Pharmacol. pmid:23278358
Liu SH et al. Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-gamma and COX-2-dependent signals. 2010 Br. J. Pharmacol. pmid:20649594