29623-28-7

29623-28-7 is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1002 references associated with 29623-28-7 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 29623-28-7

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 29623-28-7

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Thrombosis D013927 49 associated lipids
Arteriosclerosis D001161 86 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Hypertension D006973 115 associated lipids
Familial Mediterranean Fever D010505 12 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Adenomatous Polyps D018256 4 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 29623-28-7

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Authors Title Published Journal PubMed Link
Wu J et al. 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer. 2003 Carcinogenesis pmid:12584173
Nagy L et al. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. 1998 Cell pmid:9568715
Liu B et al. Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C. 1991 Cell Regul. pmid:1801923
Mani I et al. Upregulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: modulation by 13-(S)-hydroxyoctadecadienoic acid (13-HODE). 1998 Cell. Signal. pmid:9481490
Jira W et al. Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients. 1998 Chem. Phys. Lipids pmid:9488997
Batna A et al. Lipid peroxidation in presence of ebselen. 1997 Chem. Phys. Lipids pmid:9275309
Jira W et al. Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. 1997 Chem. Phys. Lipids pmid:9219348
Manini P et al. Biomimetic nitration of the linoleic acid metabolite 13-hydroxyoctadecadienoic acid: isolation and spectral characterization of novel chain-rearranged epoxy nitro derivatives. 2008 Chem. Phys. Lipids pmid:18320610
Manini P et al. Free radical oxidation of coriolic acid (13-(S)-hydroxy-9Z,11E-octadecadienoic acid). 2005 Chem. Phys. Lipids pmid:15784234
Liu W et al. Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios. 2010 Chem. Res. Toxicol. pmid:20423158
Schneider C et al. Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. 2004 Chem. Res. Toxicol. pmid:15257619
De Meyer GR et al. Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin-mediated responses in the rabbit carotid artery. 1991 Circ. Res. pmid:1645234
Klawitter J et al. Pravastatin Therapy and Biomarker Changes in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease. 2015 Clin J Am Soc Nephrol pmid:26224879
Dauchy RT et al. Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids. 2007 Comp. Med. pmid:17803052
Li MY et al. Pioglitazone prevents smoking carcinogen-induced lung tumor development in mice. 2012 Curr Cancer Drug Targets pmid:22463586
Imaizumi S et al. L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. 2010 Drug Metab Lett pmid:20642447
Jude AR et al. 13-hydroxy- and 13-oxooctadecadienoic acids: novel substrates for human UDP-glucuronosyltransferases. 2001 Drug Metab. Dispos. pmid:11302930
Chouinard S et al. Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation. 2006 Endocrinology pmid:16887906
Sakashita T et al. Essential involvement of 12-lipoxygenase in regiospecific andstereospecific oxidation of low density lipoprotein by macrophages. 1999 Eur. J. Biochem. pmid:10504415
Henricks PA et al. 13-hydroxy-linoleic acid induces airway hyperreactivity to histamine in guinea-pigs. 1991 Eur. J. Pharmacol. pmid:1915571
Buckley TL et al. 13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin. 1992 Eur. J. Pharmacol. pmid:1330604
Grøn B et al. Distribution of monohydroxy fatty acids in specific human epidermal phospholipids. 1993 Exp. Dermatol. pmid:8156169
van de Velde MJ et al. The linoleic acid metabolite 13-HODE modulates degranulation of human polymorphonuclear leukocytes. 1995 FEBS Lett. pmid:7649276
Inouye S Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid. 1984 FEBS Lett. pmid:6430718
Elékés E et al. Suppression of endotoxin mitogenicity of spleen cells by lipoxygenase inhibitors and its reversal by 13-hydroxyoctadecadienoic acid. 1993 FEMS Immunol. Med. Microbiol. pmid:8472013
Metzger K et al. Lipoxygenase products in human saliva: patients with oral cancer compared to controls. 1995 Free Radic. Biol. Med. pmid:7744301
Guo L et al. Preferential formation of the hydroperoxide of linoleic acid in choline glycerophospholipids in human erythrocytes membrane during peroxidation with an azo initiator. 1995 Free Radic. Biol. Med. pmid:7628726
Coleman JD et al. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). 2007 Free Radic. Biol. Med. pmid:17382197
Gryglewski RJ et al. Mediators produced by the endothelial cell. 1988 Hypertension pmid:3060428
Pomposiello SI et al. Linoleic acid induces relaxation and hyperpolarization of the pig coronary artery. 1998 Hypertension pmid:9461230
Czimmerer Z et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. 2012 Immunobiology pmid:22954708
Rolin J et al. Oxidized lipids and lysophosphatidylcholine induce the chemotaxis and intracellular calcium influx in natural killer cells. 2013 Immunobiology pmid:23200035
Viita H et al. 15-Lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma. 2012 Jan-Feb In Vivo pmid:22210710
Blask DE et al. Circadian stage-dependent inhibition of human breast cancer metabolism and growth by the nocturnal melatonin signal: consequences of its disruption by light at night in rats and women. 2009 Integr Cancer Ther pmid:20042410
Hübke H et al. Characterization and quantification of free and esterified 9- and 13-hydroxyoctadecadienoic acids (HODE) in barley, germinating barley, and finished malt. 2005 J. Agric. Food Chem. pmid:15740040
Cho H et al. Conjugated linoleic acid, cis-9,trans-11, is a substrate for pulmonary 15-lipoxygenase-1 in rat. 2005 J. Agric. Food Chem. pmid:16131140
Mabalirajan U et al. Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model. 2009 J. Appl. Physiol. pmid:19628725
Buchanan MR et al. 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. 1985 J. Biol. Chem. pmid:3934168
Askari B et al. Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells. 2002 J. Biol. Chem. pmid:12138107
Ek-Von Mentzer BA et al. Binding of 13-HODE and 15-HETE to phospholipid bilayers, albumin, and intracellular fatty acid binding proteins. implications for transmembrane and intracellular transport and for protection from lipid peroxidation. 2001 J. Biol. Chem. pmid:11278949
Hsi LC et al. 15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor gamma via the MAPK signaling pathway. 2001 J. Biol. Chem. pmid:11447213
Kim YS et al. The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. 2001 J. Biol. Chem. pmid:11448950
Hsi LC et al. Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. 2002 J. Biol. Chem. pmid:12189136
Hatley ME et al. Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice. 2003 J. Biol. Chem. pmid:12734208
Cimen I et al. 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma. 2011 J. Cell. Biochem. pmid:21544861
Dandona P et al. The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. 2001 J. Clin. Endocrinol. Metab. pmid:11232024
Aljada A et al. Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action? 2001 J. Clin. Endocrinol. Metab. pmid:11443197
Schild RL et al. The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids. 2002 J. Clin. Endocrinol. Metab. pmid:11889173
Aljada A et al. Troglitazone reduces the expression of PPARgamma while stimulating that of PPARalpha in mononuclear cells in obese subjects. 2001 J. Clin. Endocrinol. Metab. pmid:11443177
Han KH et al. Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma. 2000 J. Clin. Invest. pmid:10995790