29623-28-7

29623-28-7 is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1002 references associated with 29623-28-7 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 29623-28-7

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 29623-28-7

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Thrombosis D013927 49 associated lipids
Arteriosclerosis D001161 86 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Hypertension D006973 115 associated lipids
Familial Mediterranean Fever D010505 12 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Per page 10 20 | Total 11

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 29623-28-7

Download all related citations
Per page 10 20 50 100 | Total 229
Authors Title Published Journal PubMed Link
Ruparel S et al. The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. 2012 Mol Pain pmid:23006841
Zuo X and Shureiqi I Eicosanoid profiling in colon cancer: emergence of a pattern. 2013 Jul-Aug Prostaglandins Other Lipid Mediat. pmid:22960430
Ramsden CE et al. Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans. 2012 Oct-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:22959954
Czimmerer Z et al. Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages. 2012 Immunobiology pmid:22954708
Li MY et al. Pioglitazone prevents smoking carcinogen-induced lung tumor development in mice. 2012 Curr Cancer Drug Targets pmid:22463586
Pollack AZ et al. Relation of blood cadmium, lead, and mercury levels to biomarkers of lipid peroxidation in premenopausal women. 2012 Am. J. Epidemiol. pmid:22302120
Hadjiagapiou C et al. Metabolism of 13-hydroxy-9,11-octadecadienoic acid by MOLT-4 lymphocytes. 1990 Biochim. Biophys. Acta pmid:2223855
Viita H et al. 15-Lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma. 2012 Jan-Feb In Vivo pmid:22210710
Ivanov I et al. Ligand-induced formation of transient dimers of mammalian 12/15-lipoxygenase: a key to allosteric behavior of this class of enzymes? 2012 Proteins pmid:22189720
Kämmerer I et al. 13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages. 2011 Lipids Health Dis pmid:22129452
Schneider C and Pozzi A Cyclooxygenases and lipoxygenases in cancer. 2011 Cancer Metastasis Rev. pmid:22002716
Haas TA et al. Cyclic AMP regulation of endothelial cell triacylglycerol turnover, 13-hydroxyoctadecadienoic acid (13-HODE) synthesis and endothelial cell thrombogenicity. 1990 Biochim. Biophys. Acta pmid:2155665
Cimen I et al. 15-lipoxygenase-1 exerts its tumor suppressive role by inhibiting nuclear factor-kappa B via activation of PPAR gamma. 2011 J. Cell. Biochem. pmid:21544861
Huang FC and Schwab W Cloning and characterization of a 9-lipoxygenase gene induced by pathogen attack from Nicotiana benthamiana for biotechnological application. 2011 BMC Biotechnol. pmid:21450085
Chu J and Praticò D 5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo. 2011 Ann. Neurol. pmid:21280074
Ogawa E et al. Epidermal FABP (FABP5) regulates keratinocyte differentiation by 13(S)-HODE-mediated activation of the NF-κB signaling pathway. 2011 J. Invest. Dermatol. pmid:21068754
Miller CC and Ziboh VA Induction of epidermal hyperproliferation by topical n-3 polyunsaturated fatty acids on guinea pig skin linked to decreased levels of 13-hydroxyoctadecadienoic acid (13-hode). 1990 J. Invest. Dermatol. pmid:2106562
Liu SH et al. Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-gamma and COX-2-dependent signals. 2010 Br. J. Pharmacol. pmid:20649594
Imaizumi S et al. L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. 2010 Drug Metab Lett pmid:20642447
Shureiqi I et al. Profiling lipoxygenase metabolism in specific steps of colorectal tumorigenesis. 2010 Cancer Prev Res (Phila) pmid:20570882
Liu W et al. Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios. 2010 Chem. Res. Toxicol. pmid:20423158
Yuan H et al. 15-Lipoxygenases and its metabolites 15(S)-HETE and 13(S)-HODE in the development of non-small cell lung cancer. 2010 Thorax pmid:20388757
Bull AW et al. Metabolism of oxidized linoleic acid: distribution of activity for the enzymatic oxidation of 13-hydroxyoctadecadienoic acid to 13-oxooctadecadienoic acid in rat tissues. 1991 Prostaglandins pmid:2020745
Li MY et al. Roles of peroxisome proliferator-activated receptor-alpha and -gamma in the development of non-small cell lung cancer. 2010 Am. J. Respir. Cell Mol. Biol. pmid:20081051
Blask DE et al. Circadian stage-dependent inhibition of human breast cancer metabolism and growth by the nocturnal melatonin signal: consequences of its disruption by light at night in rats and women. 2009 Integr Cancer Ther pmid:20042410
Earles SM et al. Metabolism of oxidized linoleic acid: characterization of 13-hydroxyoctadecadienoic acid dehydrogenase activity from rat colonic tissue. 1991 Biochim. Biophys. Acta pmid:1998735
Aznar-Salatti J et al. Platelet adhesion to exposed endothelial cell extracellular matrixes is influenced by the method of preparation. 1991 Mar-Apr Arterioscler. Thromb. pmid:1998660
Cimen I et al. 15-Lipoxygenase-1 expression suppresses the invasive properties of colorectal carcinoma cell lines HCT-116 and HT-29. 2009 Cancer Sci. pmid:19775287
Mabalirajan U et al. Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model. 2009 J. Appl. Physiol. pmid:19628725
Wecksler AT et al. Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid. 2009 Biochemistry pmid:19469483
Kawakami Y et al. Antiproliferative activity of guava leaf extract via inhibition of prostaglandin endoperoxide H synthase isoforms. 2009 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:19457650
Baer AN et al. In vivo activation of an omega-6 oxygenase in human skin. 1991 Biochem. Biophys. Res. Commun. pmid:1930242
Chabane N et al. Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis. 2009 Arthritis Res. Ther. pmid:19296842
Henricks PA et al. 13-hydroxy-linoleic acid induces airway hyperreactivity to histamine in guinea-pigs. 1991 Eur. J. Pharmacol. pmid:1915571
Baer AN et al. Stereospecificity of the products of the fatty acid oxygenases derived from psoriatic scales. 1991 J. Lipid Res. pmid:1906083
Baer AN et al. Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells. 1991 Biochim. Biophys. Acta pmid:1892877
Wang D et al. Asymmetric dimethylarginine, oxidative stress, and vascular nitric oxide synthase in essential hypertension. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:18685064
Tloti MA et al. Effect of 13-hydroxyoctadeca-9,11-dienoic acid (13-HODE) on thrombin induced platelet adherence to endothelial cells in vitro. 1991 Thromb. Res. pmid:1866713
Manini P et al. Biomimetic nitration of the linoleic acid metabolite 13-hydroxyoctadecadienoic acid: isolation and spectral characterization of novel chain-rearranged epoxy nitro derivatives. 2008 Chem. Phys. Lipids pmid:18320610
Collins JF et al. Induction of arachidonate 12-lipoxygenase (Alox15) in intestine of iron-deficient rats correlates with the production of biologically active lipid mediators. 2008 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:18258795
Wang D et al. Asymmetric dimethylarginine and lipid peroxidation products in early autosomal dominant polycystic kidney disease. 2008 Am. J. Kidney Dis. pmid:18215696
Liu B et al. Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C. 1991 Cell Regul. pmid:1801923
Wittwer J and Hersberger M The two faces of the 15-lipoxygenase in atherosclerosis. 2007 Prostaglandins Leukot. Essent. Fatty Acids pmid:17869078
Dauchy RT et al. Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids. 2007 Comp. Med. pmid:17803052
Altmann R et al. 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. 2007 Biochem. Pharmacol. pmid:17604003
Yoshinaga M et al. The 15-lipoxygenase-1 expression may enhance the sensitivity to non-steroidal anti-inflammatory drug-induced apoptosis in colorectal cancers from patients who are treated with the compounds. 2007 J. Gastroenterol. Hepatol. pmid:17559385
Smith LC et al. Dietary fish oil deactivates a growth-promoting signaling pathway in hepatoma 7288CTC in Buffalo rats. 2006 Nutr Cancer pmid:17474866
Sauer LA et al. Dietary factors and growth and metabolism in experimental tumors. 2007 J. Nutr. Biochem. pmid:17418560
Coleman JD et al. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). 2007 Free Radic. Biol. Med. pmid:17382197
Chouinard S et al. Isoform-specific regulation of uridine diphosphate-glucuronosyltransferase 2B enzymes in the human prostate: differential consequences for androgen and bioactive lipid inactivation. 2006 Endocrinology pmid:16887906
Hampel JK et al. Differential modulation of cell cycle, apoptosis and PPARgamma2 gene expression by PPARgamma agonists ciglitazone and 9-hydroxyoctadecadienoic acid in monocytic cells. 2006 Prostaglandins Leukot. Essent. Fatty Acids pmid:16647253
Seeley SK et al. Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid. 2006 Biochim. Biophys. Acta pmid:16624487
Engels F et al. Production of arachidonic acid and linoleic acid metabolites by human bronchoalveolar lavage cells. 1991 Prostaglandins pmid:1662406
De Meyer GR et al. Early atherosclerosis is accompanied by a decreased rather than an increased accumulation of fatty acid hydroxyderivatives. 1991 Biochem. Pharmacol. pmid:1650207
De Meyer GR et al. Neointima formation impairs endothelial muscarinic receptors while enhancing prostacyclin-mediated responses in the rabbit carotid artery. 1991 Circ. Res. pmid:1645234
Shureiqi I et al. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. 2005 Cancer Res. pmid:16357157
Zuo X et al. Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity. 2006 Oncogene pmid:16288226
Kim JH et al. Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein. 2005 Biochim. Biophys. Acta pmid:16185917
Kim JS et al. Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells. 2005 Mol. Cancer Res. pmid:16179498
Sauer LA et al. Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway. 2005 J. Nutr. pmid:16140887
Cho H et al. Conjugated linoleic acid, cis-9,trans-11, is a substrate for pulmonary 15-lipoxygenase-1 in rat. 2005 J. Agric. Food Chem. pmid:16131140
Heslin MJ et al. Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. 2005 Ann. Surg. pmid:15912043
Terao J et al. Glutathione peroxidase mimics as novel antioxidants from vegetables. 2005 Biofactors pmid:15817993
Manini P et al. Free radical oxidation of coriolic acid (13-(S)-hydroxy-9Z,11E-octadecadienoic acid). 2005 Chem. Phys. Lipids pmid:15784234
Hübke H et al. Characterization and quantification of free and esterified 9- and 13-hydroxyoctadecadienoic acids (HODE) in barley, germinating barley, and finished malt. 2005 J. Agric. Food Chem. pmid:15740040
Hsi LC et al. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells. 2004 Cancer Res. pmid:15574791
Gerhardt B et al. Lipoxygenase-mediated metabolism of storage lipids in germinating sunflower cotyledons and beta-oxidation of (9Z,11E,13S)-13-hydroxy-octadeca-9,11-dienoic acid by the cotyledonary glyoxysomes. 2005 Planta pmid:15526214
Akiba S et al. Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation. 2004 Biochim. Biophys. Acta pmid:15522824
Chechetkin IR et al. The novel pathway for ketodiene oxylipin biosynthesis in Jerusalem artichoke (Helianthus tuberosus) tubers. 2004 Biochim. Biophys. Acta pmid:15522817
Schneider C et al. Autoxidative transformation of chiral omega6 hydroxy linoleic and arachidonic acids to chiral 4-hydroxy-2E-nonenal. 2004 Chem. Res. Toxicol. pmid:15257619
Lehmann WD et al. Profiling assay for lipoxygenase products of linoleic and arachidonic acid by gas chromatography-mass spectrometry. 1992 Anal. Biochem. pmid:1514683
Dauchy RT et al. Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. 2004 Cancer Lett. pmid:15145516
Tanabe M et al. Incorporation of arachidonic and linoleic acid hydroperoxides into cultured human umbilical vein endothelial cells. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120710
Jostarndt K et al. Enzymatically modified low-density lipoprotein upregulates CD36 in low-differentiated monocytic cells in a peroxisome proliferator-activated receptor-gamma-dependent way. 2004 Biochem. Pharmacol. pmid:15104237
Blask DE et al. Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin. 2004 Carcinogenesis pmid:14754876
Coutant F et al. Sensing environmental lipids by dendritic cell modulates its function. 2004 J. Immunol. pmid:14688309
Nixon JB et al. 15-Lipoxygenase-1 has anti-tumorigenic effects in colorectal cancer. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:14643174
Kandouz M et al. Platelet-type 12-lipoxygenase activates NF-kappaB in prostate cancer cells. 2003 Prostaglandins Other Lipid Mediat. pmid:14518561
De Meyer GR et al. The role of endothelial cells in the relaxations induced by 13-hydroxy- and 13-hydroperoxylinoleic acid in canine arteries. 1992 Br. J. Pharmacol. pmid:1422601
Buckley TL et al. 13-hydroxyoctadecadienoic acid attenuates oedema formation induced by leukotriene B4 in vivo in rabbit skin. 1992 Eur. J. Pharmacol. pmid:1330604
Su BN et al. Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora. 2003 J. Nat. Prod. pmid:12932130
Shureiqi I et al. The 15-lipoxygenase-1 product 13-S-hydroxyoctadecadienoic acid down-regulates PPAR-delta to induce apoptosis in colorectal cancer cells. 2003 Proc. Natl. Acad. Sci. U.S.A. pmid:12909723
Blask DE et al. Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. 2003 Breast Cancer Res. Treat. pmid:12846415
Cho H et al. Nonradiometric HPLC measurement of 13(S)-hydroxyoctadecadienoic acid from rat tissues. 2003 Anal. Biochem. pmid:12782030
Akiba S et al. Oxidized LDL activates phospholipase A2 to supply fatty acids required for cholesterol esterification. 2003 J. Lipid Res. pmid:12777475
Hatley ME et al. Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice. 2003 J. Biol. Chem. pmid:12734208
Nixon JB et al. Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711249
Wu J et al. 15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer. 2003 Carcinogenesis pmid:12584173
Pasqualini ME et al. Association between E-cadherin expression by human colon, bladder and breast cancer cells and the 13-HODE:15-HETE ratio. A possible role of their metastatic potential. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538085
Khan-Merchant N et al. Oxidized fatty acids promote atherosclerosis only in the presence of dietary cholesterol in low-density lipoprotein receptor knockout mice. 2002 J. Nutr. pmid:12421837
Hsi LC et al. Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. 2002 J. Biol. Chem. pmid:12189136
Müller K et al. Modulation of epidermal tumor development caused by targeted overexpression of epidermis-type 12S-lipoxygenase. 2002 Cancer Res. pmid:12183416
Weichert H et al. Metabolic profiling of oxylipins in germinating cucumber seedlings--lipoxygenase-dependent degradation of triacylglycerols and biosynthesis of volatile aldehydes. 2002 Planta pmid:12172844
Askari B et al. Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells. 2002 J. Biol. Chem. pmid:12138107
Müller C et al. Perturbation of lipid metabolism by linoleic acid hydroperoxide in CaCo-2 cells. 2002 Mar-Apr Biol. Chem. pmid:12033453
Schild RL et al. The activity of PPAR gamma in primary human trophoblasts is enhanced by oxidized lipids. 2002 J. Clin. Endocrinol. Metab. pmid:11889173
Fischer B et al. Dualism of oxidized lipoproteins in provoking and attenuating the oxidative burst in macrophages: role of peroxisome proliferator-activated receptor-gamma. 2002 J. Immunol. pmid:11884452
Jostarndt K et al. Dissociation of apoptosis induction and CD36 upregulation by enzymatically modified low-density lipoprotein in monocytic cells. 2002 Biochem. Biophys. Res. Commun. pmid:11798172
Kelavkar UP et al. Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. 2001 Carcinogenesis pmid:11698337
Kim YS et al. The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. 2001 J. Biol. Chem. pmid:11448950