9,10-DiHOME

9,10-dihome is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Maxillary Diseases D008439 3 associated lipids
Goat Diseases D015511 6 associated lipids
Sheep Diseases D012757 10 associated lipids
Cattle Diseases D002418 24 associated lipids
Pulmonary Edema D011654 23 associated lipids
Leukemia D007938 74 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Per page 10 20 50 | Total 29

PubChem Biomolecular Interactions and Pathways

All references with 9,10-DiHOME

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Per page 10 20 50 100 | Total 543
Authors Title Published Journal PubMed Link
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Ennibi OK et al. The highly leukotoxic JP2 clone of Aggregatibacter actinomycetemcomitans in localized and generalized forms of aggressive periodontitis. 2012 Acta Odontol. Scand. pmid:22251014
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Chang YF et al. Pasteurella haemolytica leukotoxin: chemiluminescent responses of peripheral blood leukocytes from several different mammalian species to leukotoxin- and opsonin-treated living and killed Pasteurella haemolytica and Staphylococcus aureus. 1986 Am. J. Vet. Res. pmid:3946910
Chang YF et al. Pasteurella haemolytica leukotoxin: physicochemical characteristics and susceptibility of leukotoxin to enzymatic treatment. 1986 Am. J. Vet. Res. pmid:3963575
Moore RN et al. Antileukotoxin antibody produced in the bovine lung after aerosol exposure to viable Pasteurella haemolytica. 1985 Am. J. Vet. Res. pmid:4051300
Waurzyniak BJ et al. Enhancement of Pasteurella haemolytica leukotoxic activity by bovine serum albumin. 1994 Am. J. Vet. Res. pmid:7802395
Tan ZL et al. Biological and biochemical characterization of Fusobacterium necrophorum leukotoxin. 1994 Am. J. Vet. Res. pmid:8017697
Saginala S et al. Serum neutralizing antibody response and protection against experimentally induced liver abscesses in steers vaccinated with Fusobacterium necrophorum. 1996 Am. J. Vet. Res. pmid:8712511
Scanlan CM et al. Comparative in vitro leukotoxin production of three bovine strains of Fusobacterium necrophorum. 1982 Am. J. Vet. Res. pmid:7103216
Saban R et al. Effects of Pasteurella haemolytica leukotoxin and lipopolysaccharide on histamine, prostanoid, and leukotriene release by bovine lung parenchyma in vitro. 1997 Am. J. Vet. Res. pmid:9361883
Ozawa T et al. Existence of leukotoxin 9,10-epoxy-12-octadecenoate in lung lavages from rats breathing pure oxygen and from patients with the adult respiratory distress syndrome. 1988 Am. Rev. Respir. Dis. pmid:3345035
Guo DH et al. An indirect ELISA for serodiagnosis of cattle footrot caused by Fusobacterium necrophorum. 2010 Anaerobe pmid:20304080
Tadepalli S et al. Leukotoxin operon and differential expressions of the leukotoxin gene in bovine Fusobacterium necrophorum subspecies. 2008 Anaerobe pmid:17988899
Jeyaseelan S et al. Role of Mannheimia haemolytica leukotoxin in the pathogenesis of bovine pneumonic pasteurellosis. 2002 Anim Health Res Rev pmid:12665107
Rice JA et al. Mannheimia haemolytica and bovine respiratory disease. 2007 Anim Health Res Rev pmid:18218156
Veit HP et al. Toxin production by Pasteurella granulomatis. 1998 Ann. N. Y. Acad. Sci. pmid:9668517
Ricketts AP et al. A leukotoxin nonproducing mutant of Pasteurella haemolytica. Phagocytosis and killing by bovine polymorphonucleocytes. 1994 Ann. N. Y. Acad. Sci. pmid:8080187
Henderson B et al. Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans. 2003 Annu. Rev. Microbiol. pmid:14527274
Bronner S et al. Moxifloxacin efficacy and vitreous penetration in a rabbit model of Staphylococcus aureus endophthalmitis and effect on gene expression of leucotoxins and virulence regulator factors. 2003 Antimicrob. Agents Chemother. pmid:12709331
Johansson A et al. Lack of lipoprotein-dependent effects on the cytotoxic interactions of Actinobacillus actinomycetemcomitans leukotoxin with human neutrophils. 2002 APMIS pmid:12645663
Haubek D The highly leukotoxic JP2 clone of Aggregatibacter actinomycetemcomitans: evolutionary aspects, epidemiology and etiological role in aggressive periodontitis. 2010 APMIS Suppl. pmid:21214629
Bronner S et al. Variable expressions of Staphylococcus aureus bicomponent leucotoxins semiquantified by competitive reverse transcription-PCR. 2000 Appl. Environ. Microbiol. pmid:10966411
Rotstein OD et al. A Bacteroides by-product inhibits human polymorphonuclear leukocyte function. 1986 Arch Surg pmid:3942502
Harris TR et al. Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules. 2008 Arch. Biochem. Biophys. pmid:18267101
Lawson DA et al. Molecular analysis of periodontal pathogens. 1990 Arch. Oral Biol. pmid:1965114
Ebersole JL et al. Molecular approaches to leucotoxin as a virulence component in Actinobacillus actinomycetemcomitans. 1990 Arch. Oral Biol. pmid:1708231
Baehni PC et al. Leukotoxic activity in different strains of the bacterium Actinobacillus actinomycetemcomitans isolated from juvenile periodontitis in man. 1981 Arch. Oral Biol. pmid:6172101
Iwase H et al. Monoepoxide production from linoleic acid by cytochrome c in the presence of cardiolipin. 1996 Biochem. Biophys. Res. Commun. pmid:8630079
Lally ET et al. Identification and expression of the Actinobacillus actinomycetemcomitans leukotoxin gene. 1989 Biochem. Biophys. Res. Commun. pmid:2647082
Iwase H et al. pH dependent alterations of monoepoxides and monochlorohydrins of linoleic acid, and their existence in vivo. 1995 Biochem. Biophys. Res. Commun. pmid:7488065
Hayakawa M et al. Neutrophils biosynthesize leukotoxin, 9, 10-epoxy-12-octadecenoate. 1986 Biochem. Biophys. Res. Commun. pmid:3718512
Ozawa T et al. Biosynthesis of leukotoxin, 9,10-epoxy-12 octadecenoate, by leukocytes in lung lavages of rat after exposure to hyperoxia. 1986 Biochem. Biophys. Res. Commun. pmid:3947358
Joubert O et al. Engineered covalent leucotoxin heterodimers form functional pores: insights into S-F interactions. 2006 Biochem. J. pmid:16494579
Laventie BJ et al. p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions. 2013 Biochem. J. pmid:23282185
Sato N et al. Effect of Ca2+ on the binding of Actinobacillus actinomycetemcomitans leukotoxin and the cytotoxicity to promyelocytic leukemia HL-60 cells. 1993 Biochem. Mol. Biol. Int. pmid:8508142
Zhang F et al. Secretion and circular dichroism analysis of the C-terminal signal peptides of HlyA and LktA. 1995 Biochemistry pmid:7703231
Karakelian D et al. Characterization of Actinobacillus actinomycetemcomitans leukotoxin pore formation in HL60 cells. 1998 Biochim. Biophys. Acta pmid:9573356
Reinholdt J et al. Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human β2 integrins and erythrocytes. 2013 Biochim. Biophys. Acta pmid:23234758
Lear JD et al. Conformational studies of Actinobacillus actinomycetemcomitans leukotoxin: partial denaturation enhances toxicity. 2000 Biochim. Biophys. Acta pmid:10669799
Stimers JR et al. Effects of linoleic acid metabolites on electrical activity in adult rat ventricular myocytes. 1999 Biochim. Biophys. Acta pmid:10366778
Lear JD et al. Actinobacillus actinomycetemcomitans leukotoxin forms large conductance, voltage-gated ion channels when incorporated into planar lipid bilayers. 1995 Biochim. Biophys. Acta pmid:7544624
Larsen J et al. Evolution of the leukotoxin promoter in genus Mannheimia. 2009 BMC Evol. Biol. pmid:19480674
Larsen J et al. Analysis of gene order data supports vertical inheritance of the leukotoxin operon and genome rearrangements in the 5' flanking region in genus Mannheimia. 2007 BMC Evol. Biol. pmid:17915007
Lawrence PK et al. A three-way comparative genomic analysis of Mannheimia haemolytica isolates. 2010 BMC Genomics pmid:20920355
Orrù G et al. Usefulness of real time PCR for the differentiation and quantification of 652 and JP2 Actinobacillus actinomycetemcomitans genotypes in dental plaque and saliva. 2006 BMC Infect. Dis. pmid:16772039
Johansson A et al. Prevalence of systemic immunoreactivity to Aggregatibacter actinomycetemcomitans leukotoxin in relation to the incidence of myocardial infarction. 2011 BMC Infect. Dis. pmid:21362180
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Saddi-Ortega L et al. Actinobacillus actinomycetemcomitans genetic heterogeneity: amplification of JP2-like ltx promoter pattern correlated with specific arbitrarily primed polymerase chain reaction (AP-PCR) genotypes from human but not marmoset Brazilian isolates. 2002 Can. J. Microbiol. pmid:12224559
Bowersock TL et al. Pulmonary immunity in calves following stimulation of the gut-associated lymphatic tissue by bacterial exotoxin. 1992 Can. J. Vet. Res. pmid:1591657
Bowersock TL et al. Hematological changes in calves exposed to a mixture of lipopolysaccharide and crude leukotoxin of Pasteurella haemolytica. 1990 Can. J. Vet. Res. pmid:2249175
Conlon PD et al. Effects of Pasteurella haemolytica A1 culture supernatant on mechanisms controlling bovine alveolar macrophage oxygen radical production. 1990 Can. J. Vet. Res. pmid:2357660
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