| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Maxillary Diseases | D008439 | 3 associated lipids |
| Goat Diseases | D015511 | 6 associated lipids |
| Sheep Diseases | D012757 | 10 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Pulmonary Edema | D011654 | 23 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Prosthesis-Related Infections | D016459 | 7 associated lipids |
| Fusobacterium Infections | D005674 | 3 associated lipids |
9,10-DiHOME
9,10-dihome is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME
PubChem Biomolecular Interactions and Pathways
All references with 9,10-DiHOME
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huber H et al. | Genotypes, antibiotic resistance profiles and microarray-based characterization of methicillin-resistant Staphylococcus aureus strains isolated from livestock and veterinarians in Switzerland. | 2011 | Zoonoses Public Health | pmid:20849461 |
| Wang Z et al. | [Detecting the level of Actinobacillus actinomycetemcomitans leukotoxin]. | 2000 | Zhonghua Kou Qiang Yi Xue Za Zhi | pmid:11780480 |
| Kanoe M and Inoue S | Leukotoxic activity of Clostridium perfringens of equine origin. | 1990 | Zentralblatt Veterinarmedizin Reihe B | pmid:2382518 |
| Stahl J et al. | Isolation and purification of functional bovine lung mast cells (BLMCs). | 1996 | Zentralblatt Veterinarmedizin Reihe B | pmid:8919968 |
| Ã…berg CH et al. | Aggregatibacter actinomycetemcomitans: virulence of its leukotoxin and association with aggressive periodontitis. | 2015 | Virulence | pmid:25494963 |
| Saginala S et al. | The serum neutralizing antibody response in cattle to Fusobacterium necrophorum leukotoxoid and possible protection against experimentally induced hepatic abscesses. | 1996 | Vet. Res. Commun. | pmid:8950830 |
| Confer AW et al. | Effects of Pasteurella haemolytica leukotoxin on neutrophils from white-tailed deer and several exotic ruminant species. | 1990 | Vet. Res. Commun. | pmid:2382402 |
| Sun DB et al. | Identification of three immunodominant regions on leukotoxin protein of Fusobacterium necrophorum. | 2009 | Vet. Res. Commun. | pmid:19449113 |
| Rainard P | Staphylococcus aureus leucotoxin LukM/F' is secreted and stimulates neutralising antibody response in the course of intramammary infection. | 2007 Sep-Oct | Vet. Res. | pmid:17583665 |
| Thumbikat P et al. | Characterization of Mannheimia (Pasteurella) haemolytica leukotoxin interaction with bovine alveolar macrophage beta2 integrins. | 2005 Sep-Dec | Vet. Res. | pmid:16120252 |
| Zecchinon L et al. | How Mannheimia haemolytica defeats host defence through a kiss of death mechanism. | 2005 Mar-Apr | Vet. Res. | pmid:15720968 |
| Sutherland AD and Burrells C | Interaction of red deer leucocytes with Pasteurella haemolytica leucotoxin. | 1991 | Vet. Rec. | pmid:2024415 |
| Whiteley LO et al. | Immunohistochemical localization of Pasteurella haemolytica A1-derived endotoxin, leukotoxin, and capsular polysaccharide in experimental bovine Pasteurella pneumonia. | 1990 | Vet. Pathol. | pmid:2191489 |
| Singh K et al. | Mannheimia haemolytica: bacterial-host interactions in bovine pneumonia. | 2011 | Vet. Pathol. | pmid:20685916 |
| Zhou H et al. | Identification of a leukotoxin sequence from Fusobacterium equinum. | 2009 | Vet. Microbiol. | pmid:18783899 |
| Li J et al. | Bovine CD18 identified as a species specific receptor for Pasteurella haemolytica leukotoxin. | 1999 | Vet. Microbiol. | pmid:10414364 |
| Nyarko KA et al. | Bovine platelet adhesion is enhanced by leukotoxin and sialoglycoprotease isolated from Pasteurella haemolytica A1 cultures. | 1998 | Vet. Microbiol. | pmid:9646468 |
| Basaraba RJ et al. | Actin polymerization enhances Pasteurella haemolytica leukotoxicity. | 1999 | Vet. Microbiol. | pmid:10063536 |
| Sun Y et al. | Pasteurella haemolytica leukotoxin induced apoptosis of bovine lymphocytes involves DNA fragmentation. | 1999 | Vet. Microbiol. | pmid:10078599 |
| Simpson VR et al. | Association of a lukM-positive clone of Staphylococcus aureus with fatal exudative dermatitis in red squirrels (Sciurus vulgaris). | 2013 | Vet. Microbiol. | pmid:23182436 |
| Dassanayake RP et al. | Role of Bibersteinia trehalosi, respiratory syncytial virus, and parainfluenza-3 virus in bighorn sheep pneumonia. | 2013 | Vet. Microbiol. | pmid:23025980 |
| Subramaniam R et al. | Bighorn sheep × domestic sheep hybrids survive Mannheimia haemolytica challenge in the absence of vaccination. | 2014 | Vet. Microbiol. | pmid:24629771 |
| Padmaja RJ and Halami PM | Immunogenicity of Staphylococcus aureus LukM/F'-PV recombinant subunits: validation of diagnostic potential and evaluation of protective efficacy in vitro. | 2014 | Vet. Microbiol. | pmid:24674742 |
| Narayanan SK et al. | Leukotoxins of gram-negative bacteria. | 2002 | Vet. Microbiol. | pmid:11750142 |
| Schuberth HJ et al. | Characterization of leukocytotoxic and superantigen-like factors produced by Staphylococcus aureus isolates from milk of cows with mastitis. | 2001 | Vet. Microbiol. | pmid:11423209 |
| Craig FF et al. | A colourimetric, microplate assay for the leucotoxin of Pasteurella haemolytica. | 1990 | Vet. Microbiol. | pmid:2363244 |
| McNeil HJ et al. | Novel protease produced by a Pasteurella trehalosi serotype 10 isolate from a pneumonic bighorn sheep: characteristics and potential relevance to protection. | 2003 | Vet. Microbiol. | pmid:12637002 |
| Gerbig DG et al. | Calcium ion involvement in the action of Pasteurella haemolytica leukotoxin. | 1989 | Vet. Microbiol. | pmid:2750075 |
| Gentry MJ et al. | Comparison of the toxic and antigenic properties of single bovine isolates of Pasteurella haemolytica representing five serotypes and an untypable strain. | 1988 | Vet. Microbiol. | pmid:3381490 |
| Greer CN and Shewen PE | Automated colorimetric assay for the detection of Pasteurella haemolytica leucotoxin. | 1986 | Vet. Microbiol. | pmid:3487878 |
| Tan ZL et al. | Factors affecting the leukotoxin activity of Fusobacterium necrophorum. | 1992 | Vet. Microbiol. | pmid:1514235 |
| Zhou H et al. | Identification of a Fusobacterium necrophorum isolate that contains a new variant of the leukotoxin gene (lktA) from the hoof of a sheep with ovine footrot. | 2011 | Vet. Microbiol. | pmid:21145671 |
| Mdurvwa EG and Brunner CJ | Bovine neutrophil activation by culture fluid from Pasteurella haemolytica serotypes A1 and A11. | 1994 | Vet. Microbiol. | pmid:7801531 |
| Gatewood DM et al. | Growth-condition dependent expression of Pasteurella haemolytica A1 outer membrane proteins, capsule, and leukotoxin. | 1994 | Vet. Microbiol. | pmid:7975148 |
| Zhou H et al. | Fusobacterium necrophorum variants present on the hooves of lame pigs. | 2010 | Vet. Microbiol. | pmid:19781870 |
| Srinand S et al. | Comparative evaluation of antibodies induced by commercial Pasteurella haemolytica vaccines using solid phase immunoassays. | 1996 | Vet. Microbiol. | pmid:8734636 |
| Subramaniam R et al. | Defective bacterial clearance is responsible for the enhanced lung pathology characteristic of Mannheimia haemolytica pneumonia in bighorn sheep. | 2011 | Vet. Microbiol. | pmid:21742446 |
| Tan ZL et al. | Purification and quantification of Fusobacterium necrophorum leukotoxin by using monoclonal antibodies. | 1994 | Vet. Microbiol. | pmid:7886927 |
| Lawrence PK et al. | Transfection of non-susceptible cells with Ovis aries recombinant lymphocyte function-associated antigen 1 renders susceptibility to Mannheimia haemolytica leukotoxin. | 2007 | Vet. Microbiol. | pmid:17590539 |
| DeSilva RT et al. | Partial characterization of the leukotoxin of Pasteurella haemolytica-like bacteria isolated from swine enteritis. | 1995 | Vet. Microbiol. | pmid:7483245 |
| Zhang F et al. | The two major subspecies of Fusobacterium necrophorum have distinct leukotoxin operon promoter regions. | 2006 | Vet. Microbiol. | pmid:16303263 |
| Yamada T et al. | Leukotoxin family genes in Staphylococcus aureus isolated from domestic animals and prevalence of lukM-lukF-PV genes by bacteriophages in bovine isolates. | 2005 | Vet. Microbiol. | pmid:16112825 |
| Singh K et al. | Cytokine expression by pulmonary leukocytes from calves challenged with wild-type and leukotoxin-deficient Mannheimia haemolytica. | 2012 | Vet. J. | pmid:21696986 |
| Singh K et al. | Cytotoxicity and cytokine production by bovine alveolar macrophages challenged with wild type and leukotoxin-deficient Mannheimia haemolytica. | 2011 | Vet. J. | pmid:20542456 |
| Leite F et al. | Effect of experimental infection of cattle with bovine herpesvirus-1 (BHV-1) on the ex vivo interaction of bovine leukocytes with Mannheimia (Pasteurella) haemolytica leukotoxin. | 2002 | Vet. Immunol. Immunopathol. | pmid:11825601 |
| Majury AL and Shewen PE | Preliminary investigation of the mechanism of inhibition of bovine lymphocyte proliferation by Pasteurella haemolytica A1 leukotoxin. | 1991 | Vet. Immunol. Immunopathol. | pmid:1949583 |
| Breider MA et al. | Interaction of bovine neutrophils in Pasteurella haemolytica mediated damage to pulmonary endothelial cells. | 1991 | Vet. Immunol. Immunopathol. | pmid:2038823 |
| Brunner CJ et al. | Chemotactic response of bovine neutrophils to Pasteurella haemolytica culture fluid. | 1989 | Vet. Immunol. Immunopathol. | pmid:2800327 |
| Noel EJ et al. | Preincubation of bovine blood neutrophils with bovine herpesvirus-1 does not impair neutrophil interaction with Pasteurella haemolytica A1 in vitro. | 1988 | Vet. Immunol. Immunopathol. | pmid:2855289 |
| Leite F et al. | BHV-1 infection and inflammatory cytokines amplify the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood mononuclear cells in vitro. | 2004 | Vet. Immunol. Immunopathol. | pmid:15135985 |
| Maheswaran SK et al. | Effects of Pasteurella haemolytica A1 leukotoxin on bovine neutrophils: degranulation and generation of oxygen-derived free radicals. | 1992 | Vet. Immunol. Immunopathol. | pmid:1321532 |
| Dassanayake RP et al. | Co-expression of ovine LPS receptor CD14 with Mannheimia haemolytica leukotoxin receptor LFA-1 or Mac-1 does not enhance leukotoxin-induced cytotoxicity. | 2011 | Vet. Immunol. Immunopathol. | pmid:21420740 |
| Ayalew S et al. | Intranasal vaccination of calves with Mannheimia haemolytica chimeric protein containing the major surface epitope of outer membrane lipoprotein PlpE, the neutralizing epitope of leukotoxin, and cholera toxin subunit B. | 2009 | Vet. Immunol. Immunopathol. | pmid:19581005 |
| Shanthalingam S et al. | Molecular cloning of CD18 of bison, deer and elk, and comparison with that of other ruminants and non-ruminants. | 2010 | Vet. Immunol. Immunopathol. | pmid:20176404 |
| Lawrence PK and Dassanayake RP | Ovis aries CR4 is involved in Mannheimia haemolytica leukotoxin-induced cytotoxicity. | 2010 | Vet. Immunol. Immunopathol. | pmid:20060597 |
| Lawrence PK et al. | beta(2) integrin Mac-1 is a receptor for Mannheimia haemolytica leukotoxin on bovine and ovine leukocytes. | 2008 | Vet. Immunol. Immunopathol. | pmid:18262657 |
| Leite F et al. | Incubation of bovine PMNs with conditioned medium from BHV-1 infected peripheral blood mononuclear cells increases their susceptibility to Mannheimia haemolytica leukotoxin. | 2005 | Vet. Immunol. Immunopathol. | pmid:15621305 |
| Prado ME et al. | Maternally and naturally acquired antibodies to Mannheimia haemolytica and Pasteurella multocida in beef calves. | 2006 | Vet. Immunol. Immunopathol. | pmid:16386312 |
| Confer AW et al. | Serum antibody responses of cattle vaccinated with partially purified native Pasteurella haemolytica leukotoxin. | 1997 Aug-Sep | Vaccine | pmid:9302755 |
| Confer AW et al. | Recombinant Mannheimia haemolytica serotype 1 outer membrane protein PlpE enhances commercial M. haemolytica vaccine-induced resistance against serotype 6 challenge. | 2006 | Vaccine | pmid:16430995 |
| Sreevatsan S et al. | Evaluation of three experimental subunit vaccines against pneumonic pasteurellosis in cattle. | 1996 | Vaccine | pmid:8852412 |
| Ayalew S et al. | Mannheimia haemolytica chimeric protein vaccine composed of the major surface-exposed epitope of outer membrane lipoprotein PlpE and the neutralizing epitope of leukotoxin. | 2008 | Vaccine | pmid:18675308 |
| Crouch CF et al. | Cross protection of a Mannheimia haemolytica A1 Lkt-/Pasteurella multocida ΔhyaE bovine respiratory disease vaccine against experimental challenge with Mannheimia haemolytica A6 in calves. | 2012 | Vaccine | pmid:22306859 |
| Confer AW et al. | Duration of serum antibody responses following vaccination and revaccination of cattle with non-living commercial Pasteurella haemolytica vaccines. | 1998 | Vaccine | pmid:9796051 |
| Hodgins DC and Shewen PE | Serologic responses of young colostrum fed dairy calves to antigens of Pasteurella haemolytica A1. | 1998 | Vaccine | pmid:9796059 |
| Baca-Estrada ME et al. | Effects of IL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system. | 2000 | Vaccine | pmid:10699333 |
| Hedlin PD et al. | Design and delivery of a cryptic PrP(C) epitope for induction of PrP(Sc)-specific antibody responses. | 2010 | Vaccine | pmid:19925901 |
| Conlon JA and Shewen PE | Clinical and serological evaluation of a Pasteurella haemolytica A1 capsular polysaccharide vaccine. | 1993 | Vaccine | pmid:8342324 |
| Pei Z et al. | Phenotypic changes in nonfimbriated smooth strains of Aggregatibacter actinomycetemcomitans grown in low-humidity solid medium. | 2013 | Ultrastruct Pathol | pmid:23573892 |
| Lally ET et al. | The interaction between RTX toxins and target cells. | 1999 | Trends Microbiol. | pmid:10470043 |
| Abouna GM et al. | Comparison of the effect of plasmapheresis using human albumin or dextran 40 on the survival of pig-to-dog renal xenografts. | 1996 | Transplant. Proc. | pmid:8644183 |
| Forman MS et al. | Gangliosides block Aggregatibacter Actinomycetemcomitans leukotoxin (LtxA)-mediated hemolysis. | 2010 | Toxins (Basel) | pmid:22069577 |
| Johansson A | Aggregatibacter actinomycetemcomitans leukotoxin: a powerful tool with capacity to cause imbalance in the host inflammatory response. | 2011 | Toxins (Basel) | pmid:22069708 |
| Clinkenbeard KD et al. | Effects of Pasteurella haemolytica leukotoxin on isolated bovine neutrophils. | 1989 | Toxicon | pmid:2781580 |
| Pruett TL et al. | Mechanism of the adjuvant effect of hemoglobin in experimental peritonitis: VIII. A leukotoxin is produced by Escherichia coli metabolism in hemoglobin. | 1984 | Surgery | pmid:6379961 |
| Tervahartiala B et al. | Outer membranous vesicles and leukotoxic activity of Actinobacillus actinomycetemcomitans from subjects with different periodontal status. | 1989 | Scand J Dent Res | pmid:2711122 |
| Jaramillo ML et al. | [Mechanisms of pathogenicity and adhesion in Pasteurella haemolytica]. | 1999 Apr-Jun | Rev. Latinoam. Microbiol. | pmid:10932756 |
| RamÃrez-Romero R and Brogden KA | [Pathogenesis of lung damage caused by Pasteurella haemolytica]. | 1995 Oct-Dec | Rev. Latinoam. Microbiol. | pmid:8900571 |
| Spitznagel JK | Microbial interactions with neutrophils. | 1983 Sep-Oct | Rev. Infect. Dis. | pmid:6314473 |
| Kolodrubetz D et al. | Anaerobic regulation of Actinobacillus actinomycetemcomitans leukotoxin transcription is ArcA/FnrA-independent and requires a novel promoter element. | 2003 | Res. Microbiol. | pmid:14596902 |
| Okamura S et al. | Leukotoxin-activated human pulmonary artery endothelial cell produces nitric oxide and superoxide anion. | 2002 | Pulm Pharmacol Ther | pmid:11969361 |
| Roblin P et al. | A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins. | 2008 | Proteins | pmid:18214982 |
| Kachlany SC et al. | Purification of secreted leukotoxin (LtxA) from Actinobacillus actinomycetemcomitans. | 2002 | Protein Expr. Purif. | pmid:12182827 |
| Podolin PL et al. | In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor. | 2013 Jul-Aug | Prostaglandins Other Lipid Mediat. | pmid:23434473 |
| Shanthalingam S and Srikumaran S | Intact signal peptide of CD18, the beta-subunit of beta2-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19706410 |
| Laventie BJ et al. | Heavy chain-only antibodies and tetravalent bispecific antibody neutralizing Staphylococcus aureus leukotoxins. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21930905 |
| Zhang F et al. | Functional replacement of the hemolysin A transport signal by a different primary sequence. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8483936 |
| Rózalski A | [Cytolysins and homologous proteins produced by gram-negative bacteria. I. Hemolysis and leukotoxins of Escherichia coli, Bordetella pertussis, Pasteurella haemolytica and Actinobacillus sp]. | 1996 | Postepy Hig Med Dosw | pmid:8848425 |
| Wessely-Szponder J et al. | Effect of leukotoxin of Mannheimia haemolytica and LPS of E. coli on secretory response of bovine neutrophils in vitro. | 2005 | Pol J Vet Sci | pmid:15989128 |
| Wernicki A et al. | The influence of transport stress on the humoral immunological response of calves induced by Mannheimia haemolytica leukotoxin. | 2003 | Pol J Vet Sci | pmid:12675467 |
| Urban-Chmiel R et al. | Evaluation of Mannheimia haemolytica leukotoxin prepared in nonsupplemented and BSA or FBS supplemented RPMI 1640 medium. | 2004 | Pol J Vet Sci | pmid:15061478 |
| Wernicki A et al. | Comparison of immunogenic properties of native and inactivated Mannheimia haemolytica Lkt in calves. | 2008 | Pol J Vet Sci | pmid:18683535 |
| Alonzo F and Torres VJ | Bacterial survival amidst an immune onslaught: the contribution of the Staphylococcus aureus leukotoxins. | 2013 | PLoS Pathog. | pmid:23436994 |
| Schreiner H et al. | A comparison of Aggregatibacter actinomycetemcomitans (Aa) virulence traits in a rat model for periodontal disease. | 2013 | PLoS ONE | pmid:23936002 |
| Velusamy SK et al. | Profound Effects of Aggregatibacter actinomycetemcomitans Leukotoxin Mutation on Adherence Properties Are Clarified in in vitro Experiments. | 2016 | PLoS ONE | pmid:26977924 |
| Nieman DC et al. | Influence of pistachios on performance and exercise-induced inflammation, oxidative stress, immune dysfunction, and metabolite shifts in cyclists: a randomized, crossover trial. | 2014 | PLoS ONE | pmid:25409020 |
| Höglund Åberg C et al. | Leukotoxic activity of Aggregatibacter actinomycetemcomitans and periodontal attachment loss. | 2014 | PLoS ONE | pmid:25093857 |
| Malachowa N et al. | Global changes in Staphylococcus aureus gene expression in human blood. | 2011 | PLoS ONE | pmid:21525981 |
| Ventura CL et al. | Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics. | 2010 | PLoS ONE | pmid:20661294 |
| Hioe CE et al. | HIV envelope gp120 activates LFA-1 on CD4 T-lymphocytes and increases cell susceptibility to LFA-1-targeting leukotoxin (LtxA). | 2011 | PLoS ONE | pmid:21850260 |