9,10-DiHOME

9,10-dihome is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Maxillary Diseases D008439 3 associated lipids
Goat Diseases D015511 6 associated lipids
Sheep Diseases D012757 10 associated lipids
Cattle Diseases D002418 24 associated lipids
Pulmonary Edema D011654 23 associated lipids
Leukemia D007938 74 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Per page 10 20 50 | Total 29

PubChem Biomolecular Interactions and Pathways

All references with 9,10-DiHOME

Download all related citations
Per page 10 20 50 100 | Total 543
Authors Title Published Journal PubMed Link
Fagerberg SK et al. Inhibition of P2X Receptors Protects Human Monocytes against Damage by Leukotoxin from Aggregatibacter actinomycetemcomitans and α-Hemolysin from Escherichia coli. 2016 Infect. Immun. pmid:27528275
Webb JN et al. Inhibition of Bacterial Toxin Activity by the Nuclear Stain, DRAQ5â„¢. 2016 J. Membr. Biol. pmid:27039399
Velusamy SK et al. Profound Effects of Aggregatibacter actinomycetemcomitans Leukotoxin Mutation on Adherence Properties Are Clarified in in vitro Experiments. 2016 PLoS ONE pmid:26977924
Nocadello S et al. Crystal structures of the components of the Staphylococcus aureus leukotoxin ED. 2016 Acta Crystallogr D Struct Biol pmid:26894539
Balashova N et al. Aggregatibacter actinomycetemcomitans leukotoxin induces cytosol acidification in LFA-1 expressing immune cells. 2016 Mol Oral Microbiol pmid:26361372
Brown AC et al. Inhibition of LtxA toxicity by blocking cholesterol binding with peptides. 2016 Mol Oral Microbiol pmid:26352738
Smith KP et al. The conserved carboxyl domain of MorC, an inner membrane protein of Aggregatibacter actinomycetemcomitans, is essential for membrane function. 2016 Mol Oral Microbiol pmid:26205976
Kachlany SC Mechanisms of LtxA (Leukotoxin), a Potent New Anti-Inflammatory Agent for the Treatment of Alopecia Areata. 2015 J. Investig. Dermatol. Symp. Proc. pmid:26551939
Batra SA et al. Acylation Enhances, but Is Not Required for, the Cytotoxic Activity of Mannheimia haemolytica Leukotoxin in Bighorn Sheep. 2015 Infect. Immun. pmid:26216418
Turner CE and Sriskandan S Panton-Valentine leucocidin expression by Staphylococcus aureus exposed to common antibiotics. 2015 J. Infect. pmid:26028260
DiFranco KM et al. LFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes. 2015 Leuk. Res. pmid:25850729
Ã…berg CH et al. Aggregatibacter actinomycetemcomitans: virulence of its leukotoxin and association with aggressive periodontitis. 2015 Virulence pmid:25494963
DuMont AL et al. Identification of a crucial residue required for Staphylococcus aureus LukAB cytotoxicity and receptor recognition. 2014 Infect. Immun. pmid:24379286
Subramaniam R et al. Bighorn sheep × domestic sheep hybrids survive Mannheimia haemolytica challenge in the absence of vaccination. 2014 Vet. Microbiol. pmid:24629771
Munksgaard PS et al. Sialic acid residues are essential for cell lysis mediated by leukotoxin from Aggregatibacter actinomycetemcomitans. 2014 Infect. Immun. pmid:24643533
Padmaja RJ and Halami PM Immunogenicity of Staphylococcus aureus LukM/F'-PV recombinant subunits: validation of diagnostic potential and evaluation of protective efficacy in vitro. 2014 Vet. Microbiol. pmid:24674742
Nieman DC et al. Influence of pistachios on performance and exercise-induced inflammation, oxidative stress, immune dysfunction, and metabolite shifts in cyclists: a randomized, crossover trial. 2014 PLoS ONE pmid:25409020
Kaur M and Kachlany SC Aggregatibacter actinomycetemcomitans leukotoxin (LtxA; Leukothera) induces cofilin dephosphorylation and actin depolymerization during killing of malignant monocytes. 2014 Microbiology (Reading, Engl.) pmid:25169107
Höglund Åberg C et al. Leukotoxic activity of Aggregatibacter actinomycetemcomitans and periodontal attachment loss. 2014 PLoS ONE pmid:25093857
Silveira VR et al. Leukotoxicity of Aggregatibacter actinomycetemcomitans in generalized aggressive periodontitis in Brazilians and their family members. 2013 Sep-Oct J Appl Oral Sci pmid:24212989
Podolin PL et al. In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor. 2013 Jul-Aug Prostaglandins Other Lipid Mediat. pmid:23434473
Dietmann A et al. Effects of Aggregatibacter actinomycetemcomitans leukotoxin on endothelial cells. 2013 Aug-Sep Microb. Pathog. pmid:23665198
Yoong P and Torres VJ The effects of Staphylococcus aureus leukotoxins on the host: cell lysis and beyond. 2013 Curr. Opin. Microbiol. pmid:23466211
Alonzo F and Torres VJ Bacterial survival amidst an immune onslaught: the contribution of the Staphylococcus aureus leukotoxins. 2013 PLoS Pathog. pmid:23436994
Childress C et al. Mlc is a transcriptional activator with a key role in integrating cyclic AMP receptor protein and integration host factor regulation of leukotoxin RNA synthesis in Aggregatibacter actinomycetemcomitans. 2013 J. Bacteriol. pmid:23475968
Brown AC et al. Aggregatibacter actinomycetemcomitans leukotoxin utilizes a cholesterol recognition/amino acid consensus site for membrane association. 2013 J. Biol. Chem. pmid:23792963
Aslam R et al. Activation of neutrophils by the two-component leukotoxin LukE/D from Staphylococcus aureus: proteomic analysis of the secretions. 2013 J. Proteome Res. pmid:23834436
Martinez-Martinez RE et al. Characterization of periodontal biofilm in Down syndrome patients: a comparative study. 2013 J Clin Pediatr Dent pmid:23855174
Laventie BJ et al. p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactions. 2013 Biochem. J. pmid:23282185
Reinholdt J et al. Monodisperse and LPS-free Aggregatibacter actinomycetemcomitans leukotoxin: interactions with human β2 integrins and erythrocytes. 2013 Biochim. Biophys. Acta pmid:23234758
Alonzo F et al. CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. 2013 Nature pmid:23235831
Huang Y et al. Comparative genomic hybridization and transcriptome analysis with a pan-genome microarray reveal distinctions between JP2 and non-JP2 genotypes of Aggregatibacter actinomycetemcomitans. 2013 Mol Oral Microbiol pmid:23194436
Simpson VR et al. Association of a lukM-positive clone of Staphylococcus aureus with fatal exudative dermatitis in red squirrels (Sciurus vulgaris). 2013 Vet. Microbiol. pmid:23182436
Stevens RH et al. Prophage induction in lysogenic Aggregatibacter actinomycetemcomitans cells co-cultured with human gingival fibroblasts, and its effect on leukotoxin release. 2013 Microb. Pathog. pmid:23022667
Dassanayake RP et al. Role of Bibersteinia trehalosi, respiratory syncytial virus, and parainfluenza-3 virus in bighorn sheep pneumonia. 2013 Vet. Microbiol. pmid:23025980
Pei Z et al. Phenotypic changes in nonfimbriated smooth strains of Aggregatibacter actinomycetemcomitans grown in low-humidity solid medium. 2013 Ultrastruct Pathol pmid:23573892
Miller MW et al. Phylogenetic and epidemiologic relationships among Pasteurellaceae from Colorado bighorn sheep herds. 2013 J. Wildl. Dis. pmid:23778616
Kumar A et al. Characterization of Fusobacterium necrophorum isolated from llama and alpaca. 2013 J. Vet. Diagn. Invest. pmid:23780933
Schreiner H et al. A comparison of Aggregatibacter actinomycetemcomitans (Aa) virulence traits in a rat model for periodontal disease. 2013 PLoS ONE pmid:23936002
DiFranco KM et al. Leukotoxin kills rodent WBC by targeting leukocyte function associated antigen 1. 2013 Comp. Med. pmid:24209968
Walters MJ et al. Membrane association and destabilization by Aggregatibacter actinomycetemcomitans leukotoxin requires changes in secondary structures. 2013 Mol Oral Microbiol pmid:23678967
Ennibi OK et al. The highly leukotoxic JP2 clone of Aggregatibacter actinomycetemcomitans in localized and generalized forms of aggressive periodontitis. 2012 Acta Odontol. Scand. pmid:22251014
Crouch CF et al. Cross protection of a Mannheimia haemolytica A1 Lkt-/Pasteurella multocida ΔhyaE bovine respiratory disease vaccine against experimental challenge with Mannheimia haemolytica A6 in calves. 2012 Vaccine pmid:22306859
Brown AC et al. Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization. 2012 Cell. Microbiol. pmid:22309134
Munksgaard PS et al. Leukotoxin from Aggregatibacter actinomycetemcomitans causes shrinkage and P2X receptor-dependent lysis of human erythrocytes. 2012 Cell. Microbiol. pmid:22906303
Conceição T et al. Staphylococcus aureus reservoirs and transmission routes in a Portuguese Neonatal Intensive Care Unit: a 30-month surveillance study. 2012 Microb. Drug Resist. pmid:22191392
DiFranco KM et al. Leukotoxin (Leukothera®) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway. 2012 J. Biol. Chem. pmid:22467872
Bandhaya P et al. Aggregatibacter actinomycetemcomitans serotypes, the JP2 clone and cytolethal distending toxin genes in a Thai population. 2012 J. Clin. Periodontol. pmid:22471788
Ã…berg CH et al. Presence of JP2 and Non-JP2 Genotypes of Aggregatibacter actinomycetemcomitans and attachment loss in adolescents in Ghana. 2012 J. Periodontol. pmid:22376208
Tang G et al. Lipopolysaccharides mediate leukotoxin secretion in Aggregatibacter actinomycetemcomitans. 2012 Mol Oral Microbiol pmid:22394466

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