| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Maxillary Diseases | D008439 | 3 associated lipids |
| Goat Diseases | D015511 | 6 associated lipids |
| Sheep Diseases | D012757 | 10 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Pulmonary Edema | D011654 | 23 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Prosthesis-Related Infections | D016459 | 7 associated lipids |
| Fusobacterium Infections | D005674 | 3 associated lipids |
9,10-DiHOME
9,10-dihome is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME
PubChem Biomolecular Interactions and Pathways
All references with 9,10-DiHOME
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sun DB et al. | Identification of three immunodominant regions on leukotoxin protein of Fusobacterium necrophorum. | 2009 | Vet. Res. Commun. | pmid:19449113 |
| Balashova NV et al. | Aggregatibacter actinomycetemcomitans LtxC is required for leukotoxin activity and initial interaction between toxin and host cells. | 2009 | Gene | pmid:19450669 |
| Larsen J et al. | Evolution of the leukotoxin promoter in genus Mannheimia. | 2009 | BMC Evol. Biol. | pmid:19480674 |
| Ayalew S et al. | Intranasal vaccination of calves with Mannheimia haemolytica chimeric protein containing the major surface epitope of outer membrane lipoprotein PlpE, the neutralizing epitope of leukotoxin, and cholera toxin subunit B. | 2009 | Vet. Immunol. Immunopathol. | pmid:19581005 |
| Aberg CH et al. | Presence of Aggregatibacter actinomycetemcomitans in young individuals: a 16-year clinical and microbiological follow-up study. | 2009 | J. Clin. Periodontol. | pmid:19678862 |
| Kawamoto D et al. | Genetic diversity and toxic activity of Aggregatibacter actinomycetemcomitans isolates. | 2009 | Oral Microbiol. Immunol. | pmid:19832802 |
| Kim TS et al. | Serotypes of Aggregatibacter actinomycetemcomitans in patients with different ethnic backgrounds. | 2009 | J. Periodontol. | pmid:19961385 |
| Fett T et al. | Mannheimia haemolytica leukotoxin-induced cytolysis of caprine (Capra hircus) leukocytes is mediated by the CD18 subunit of beta2-integrins. | 2008 Nov-Dec | Microb. Pathog. | pmid:18775487 |
| Isaza MP et al. | Screen for leukotoxin mutants in Aggregatibacter actinomycetemcomitans: genes of the phosphotransferase system are required for leukotoxin biosynthesis. | 2008 | Infect. Immun. | pmid:18541661 |
| Venketaraman V et al. | Both leukotoxin and poly-N-acetylglucosamine surface polysaccharide protect Aggregatibacter actinomycetemcomitans cells from macrophage killing. | 2008 | Microb. Pathog. | pmid:18573331 |
| Ayalew S et al. | Mannheimia haemolytica chimeric protein vaccine composed of the major surface-exposed epitope of outer membrane lipoprotein PlpE and the neutralizing epitope of leukotoxin. | 2008 | Vaccine | pmid:18675308 |
| Dassanayake RP et al. | Bighorn sheep beta2-integrin LFA-1 serves as a receptor for Mannheimia haemolytica leukotoxin. | 2008 | J. Wildl. Dis. | pmid:18689665 |
| Takashima E and Konishi K | Characterization of a quinol peroxidase mutant in Aggregatibacter actinomycetemcomitans. | 2008 | FEMS Microbiol. Lett. | pmid:18616592 |
| Gallant CV et al. | Membrane morphology and leukotoxin secretion are associated with a novel membrane protein of Aggregatibacter actinomycetemcomitans. | 2008 | J. Bacteriol. | pmid:18621903 |
| Baum MS | Destroying malignant white cells. | 2008 | J N J Dent Assoc | pmid:18557488 |
| Atapattu DN et al. | Dynamin-2-dependent targeting of mannheimia haemolytica leukotoxin to mitochondrial cyclophilin D in bovine lymphoblastoid cells. | 2008 | Infect. Immun. | pmid:18765728 |
| Wang D et al. | Molecular mimicry of Aggregatibacter actinomycetemcomitans with beta2 glycoprotein I. | 2008 | Oral Microbiol. Immunol. | pmid:18793363 |
| Harris TR et al. | Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules. | 2008 | Arch. Biochem. Biophys. | pmid:18267101 |
| Wernicki A et al. | Comparison of immunogenic properties of native and inactivated Mannheimia haemolytica Lkt in calves. | 2008 | Pol J Vet Sci | pmid:18683535 |
| Kelk P et al. | IL-1beta secretion induced by Aggregatibacter (Actinobacillus) actinomycetemcomitans is mainly caused by the leukotoxin. | 2008 | Int. J. Med. Microbiol. | pmid:17888725 |
| Tadepalli S et al. | Leukotoxin operon and differential expressions of the leukotoxin gene in bovine Fusobacterium necrophorum subspecies. | 2008 | Anaerobe | pmid:17988899 |
| McClenahan D et al. | Effects of lipopolysaccharide and Mannheimia haemolytica leukotoxin on bovine lung microvascular endothelial cells and alveolar epithelial cells. | 2008 | Clin. Vaccine Immunol. | pmid:18032592 |
| Schaeffer LM et al. | Induction of Aggregatibacter actinomycetemcomitans leukotoxin expression by IS1301 and orfA. | 2008 | Microbiology (Reading, Engl.) | pmid:18227257 |
| Tadepalli S et al. | Human Fusobacterium necrophorum strains have a leukotoxin gene and exhibit leukotoxic activity. | 2008 | J. Med. Microbiol. | pmid:18201990 |
| Roblin P et al. | A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins. | 2008 | Proteins | pmid:18214982 |
| du Preez JC et al. | Kinetics of growth and leukotoxin production by Mannheimia haemolytica in continuous culture. | 2008 | J. Ind. Microbiol. Biotechnol. | pmid:18283506 |
| Lawrence PK et al. | beta(2) integrin Mac-1 is a receptor for Mannheimia haemolytica leukotoxin on bovine and ovine leukocytes. | 2008 | Vet. Immunol. Immunopathol. | pmid:18262657 |
| Rainard P | Staphylococcus aureus leucotoxin LukM/F' is secreted and stimulates neutralising antibody response in the course of intramammary infection. | 2007 Sep-Oct | Vet. Res. | pmid:17583665 |
| Dassanayake RP et al. | Mannheimia haemolytica leukotoxin-induced cytolysis of ovine (Ovis aries) leukocytes is mediated by CD18, the beta subunit of beta2-integrins. | 2007 May-Jun | Microb. Pathog. | pmid:17368825 |
| Kieba IR et al. | Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. | 2007 | Cell. Microbiol. | pmid:17587330 |
| Crosby JA and Kachlany SC | TdeA, a TolC-like protein required for toxin and drug export in Aggregatibacter (Actinobacillus) actinomycetemcomitans. | 2007 | Gene | pmid:17116373 |
| Larsen J et al. | Analysis of gene order data supports vertical inheritance of the leukotoxin operon and genome rearrangements in the 5' flanking region in genus Mannheimia. | 2007 | BMC Evol. Biol. | pmid:17915007 |
| Kanangat S et al. | Modulation of virulence gene expression in Staphylococcus aureus by interleukin-1beta: novel implications in bacterial pathogenesis. | 2007 | Microbes Infect. | pmid:17307379 |
| Dileepan T et al. | Integrin-EGF-3 domain of bovine CD18 is critical for Mannheimia haemolytica leukotoxin species-specific susceptibility. | 2007 | FEMS Microbiol. Lett. | pmid:17590223 |
| Lawrence PK et al. | Transfection of non-susceptible cells with Ovis aries recombinant lymphocyte function-associated antigen 1 renders susceptibility to Mannheimia haemolytica leukotoxin. | 2007 | Vet. Microbiol. | pmid:17590539 |
| van Rensburg E and du Preez JC | Effect of pH, temperature and nutrient limitations on growth and leukotoxin production by Mannheimia haemolytica in batch and continuous culture. | 2007 | J. Appl. Microbiol. | pmid:17448162 |
| Liu W et al. | Mannheimia (Pasteurella) haemolytica leukotoxin utilizes CD18 as its receptor on bighorn sheep leukocytes. | 2007 | J. Wildl. Dis. | pmid:17347395 |
| Atapattu DN and Czuprynski CJ | Mannheimia haemolytica leukotoxin binds to lipid rafts in bovine lymphoblastoid cells and is internalized in a dynamin-2- and clathrin-dependent manner. | 2007 | Infect. Immun. | pmid:17682044 |
| Dileepan T et al. | Human CD18 is the functional receptor for Aggregatibacter actinomycetemcomitans leukotoxin. | 2007 | Infect. Immun. | pmid:17635865 |
| Balashova NV et al. | Interaction between leukotoxin and Cu,Zn superoxide dismutase in Aggregatibacter actinomycetemcomitans. | 2007 | Infect. Immun. | pmid:17635874 |
| Rice JA et al. | Mannheimia haemolytica and bovine respiratory disease. | 2007 | Anim Health Res Rev | pmid:18218156 |
| Dassanayake RP et al. | Monomeric expression of bovine beta2-integrin subunits reveals their role in Mannheimia haemolytica leukotoxin-induced biological effects. | 2007 | Infect. Immun. | pmid:17698568 |
| Larsen J et al. | Evidence for vertical inheritance and loss of the leukotoxin operon in genus Mannheimia. | 2007 | J. Mol. Evol. | pmid:17437147 |
| de Haar SF et al. | Role of polymorphonuclear leukocyte-derived serine proteinases in defense against Actinobacillus actinomycetemcomitans. | 2006 | Infect. Immun. | pmid:16926422 |
| Wu H et al. | Inactivation of DNA adenine methyltransferase alters virulence factors in Actinobacillus actinomycetemcomitans. | 2006 | Oral Microbiol. Immunol. | pmid:16842508 |
| Confer AW et al. | Recombinant Mannheimia haemolytica serotype 1 outer membrane protein PlpE enhances commercial M. haemolytica vaccine-induced resistance against serotype 6 challenge. | 2006 | Vaccine | pmid:16430995 |
| Joubert O et al. | Engineered covalent leucotoxin heterodimers form functional pores: insights into S-F interactions. | 2006 | Biochem. J. | pmid:16494579 |
| Balashova NV et al. | Regulation of Aggregatibacter (Actinobacillus) actinomycetemcomitans leukotoxin secretion by iron. | 2006 | J. Bacteriol. | pmid:17041062 |
| Haubek D et al. | Aggressive periodontitis in a 16-year-old Ghanaian adolescent, the original source of Actinobacillus actinomycetemcomitans strain HK1651 - a 10-year follow up. | 2006 | Int J Paediatr Dent | pmid:16879336 |
| Balashova NV et al. | Leukotoxin confers beta-hemolytic activity to Actinobacillus actinomycetemcomitans. | 2006 | Infect. Immun. | pmid:16552030 |
| Fong KP et al. | Actinobacillus actinomycetemcomitans leukotoxin requires lipid microdomains for target cell cytotoxicity. | 2006 | Cell. Microbiol. | pmid:16827908 |
| Orrù G et al. | Usefulness of real time PCR for the differentiation and quantification of 652 and JP2 Actinobacillus actinomycetemcomitans genotypes in dental plaque and saliva. | 2006 | BMC Infect. Dis. | pmid:16772039 |
| Gatto NT et al. | Lung lesions in SCID-bo and SCID-bg mice after intratracheal inoculation with wild-type or leucotoxin-deficient mutant strains of Mannheimia haemolytica serotype 1. | 2006 | J. Comp. Pathol. | pmid:16712865 |
| Van Rensburg E et al. | Quantification of Mannheimia haemolytica leukotoxin by indirect ELISA. | 2006 | Onderstepoort J. Vet. Res. | pmid:17283723 |
| Permpanich P et al. | Resistance of fluorescent-labelled Actinobacillus actinomycetemcomitans strains to phagocytosis and killing by human neutrophils. | 2006 | Cell. Microbiol. | pmid:16367867 |
| Prado ME et al. | Maternally and naturally acquired antibodies to Mannheimia haemolytica and Pasteurella multocida in beef calves. | 2006 | Vet. Immunol. Immunopathol. | pmid:16386312 |
| Zhang F et al. | The two major subspecies of Fusobacterium necrophorum have distinct leukotoxin operon promoter regions. | 2006 | Vet. Microbiol. | pmid:16303263 |
| Thumbikat P et al. | Characterization of Mannheimia (Pasteurella) haemolytica leukotoxin interaction with bovine alveolar macrophage beta2 integrins. | 2005 Sep-Dec | Vet. Res. | pmid:16120252 |
| Zecchinon L et al. | How Mannheimia haemolytica defeats host defence through a kiss of death mechanism. | 2005 Mar-Apr | Vet. Res. | pmid:15720968 |
| Cortelli JR et al. | Prevalence of periodontal pathogens in Brazilians with aggressive or chronic periodontitis. | 2005 | J. Clin. Periodontol. | pmid:15998269 |
| Cortelli SC et al. | Detection of Actinobacillus actinomycetemcomitans in unstimulated saliva of patients with chronic periodontitis. | 2005 | J. Periodontol. | pmid:15974843 |
| Johansson A et al. | The immunoreactivity of systemic antibodies to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in adult periodontitis. | 2005 | Eur. J. Oral Sci. | pmid:15953243 |
| Wessely-Szponder J et al. | Effect of leukotoxin of Mannheimia haemolytica and LPS of E. coli on secretory response of bovine neutrophils in vitro. | 2005 | Pol J Vet Sci | pmid:15989128 |
| Eriksen KT et al. | Intragenomic recombination in the highly leukotoxic JP2 clone of Actinobacillus actinomycetemcomitans. | 2005 | Microbiology (Reading, Engl.) | pmid:16207919 |
| Johansson A et al. | Systemic antibodies to the leukotoxin of the oral pathogen Actinobacillus actinomycetemcomitans correlate negatively with stroke in women. | 2005 | Cerebrovasc. Dis. | pmid:16123541 |
| Kelk P et al. | Abundant secretion of bioactive interleukin-1beta by human macrophages induced by Actinobacillus actinomycetemcomitans leukotoxin. | 2005 | Infect. Immun. | pmid:15618184 |
| Leite F et al. | Incubation of bovine PMNs with conditioned medium from BHV-1 infected peripheral blood mononuclear cells increases their susceptibility to Mannheimia haemolytica leukotoxin. | 2005 | Vet. Immunol. Immunopathol. | pmid:15621305 |
| Foster TJ | Immune evasion by staphylococci. | 2005 | Nat. Rev. Microbiol. | pmid:16322743 |
| Belibasakis GN et al. | The cytolethal distending toxin induces receptor activator of NF-kappaB ligand expression in human gingival fibroblasts and periodontal ligament cells. | 2005 | Infect. Immun. | pmid:15618171 |
| Yamada T et al. | Leukotoxin family genes in Staphylococcus aureus isolated from domestic animals and prevalence of lukM-lukF-PV genes by bacteriophages in bovine isolates. | 2005 | Vet. Microbiol. | pmid:16112825 |
| Atapattu DN and Czuprynski CJ | Mannheimia haemolytica leukotoxin induces apoptosis of bovine lymphoblastoid cells (BL-3) via a caspase-9-dependent mitochondrial pathway. | 2005 | Infect. Immun. | pmid:16113266 |
| Gopinath RS et al. | Mannheimia (Pasteurella) haemolytica leukotoxin binding domain lies within amino acids 1 to 291 of bovine CD18. | 2005 | Infect. Immun. | pmid:16113344 |
| Leung WK et al. | Characterization of Actinobacillus actinomycetemcomitans isolated from young Chinese aggressive periodontitis patients. | 2005 | J. Periodont. Res. | pmid:15853973 |
| von Eiff C et al. | Prevalence of genes encoding for members of the staphylococcal leukotoxin family among clinical isolates of Staphylococcus aureus. | 2004 | Diagn. Microbiol. Infect. Dis. | pmid:15246504 |
| Harvey VL and Stephens GJ | Mechanism of GABA receptor-mediated inhibition of spontaneous GABA release onto cerebellar Purkinje cells. | 2004 | Eur. J. Neurosci. | pmid:15255979 |
| Guillet V et al. | Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins. | 2004 | J. Biol. Chem. | pmid:15262988 |
| Urban-Chmiel R et al. | Evaluation of Mannheimia haemolytica leukotoxin prepared in nonsupplemented and BSA or FBS supplemented RPMI 1640 medium. | 2004 | Pol J Vet Sci | pmid:15061478 |
| Le Quéré V et al. | Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides. | 2004 | J. Lipid Res. | pmid:15145985 |
| Leite F et al. | BHV-1 infection and inflammatory cytokines amplify the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood mononuclear cells in vitro. | 2004 | Vet. Immunol. Immunopathol. | pmid:15135985 |
| Malazdrewich C et al. | Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages. | 2004 | Microb. Pathog. | pmid:14726234 |
| Guillet V et al. | Crystallization and preliminary crystallographic data of a leucotoxin S component from Staphylococcus aureus. | 2004 | Acta Crystallogr. D Biol. Crystallogr. | pmid:14747708 |
| Yamaguchi N et al. | Tumor necrosis factor alpha enhances Actinobacillus actinomycetemcomitans leukotoxin-induced HL-60 cell apoptosis by stimulating lymphocyte function-associated antigen 1 expression. | 2004 | Infect. Immun. | pmid:14688105 |
| Haubek D and Westergaard J | Detection of a highly toxic clone of Actinobacillus actinomycetemcomitans (JP2) in a Moroccan immigrant family with multiple cases of localized aggressive periodontitis. | 2004 | Int J Paediatr Dent | pmid:14706027 |
| Mena-Rojas E et al. | Antigenic secreted proteins from Haemophilus paragallinarum. A 110-kDa putative RTX protein. | 2004 | FEMS Microbiol. Lett. | pmid:15019738 |
| Futagawa-Saito K et al. | Prevalence and characterization of leukotoxin-producing Staphylococcus intermedius in Isolates from dogs and pigeons. | 2004 | J. Clin. Microbiol. | pmid:15528733 |
| Cortelli SC et al. | Detection of highly and minimally leukotoxic Actinobacillus actinomycetemcomitans strains in patients with periodontal disease. | 2003 Apr-Jun | Pesqui Odontol Bras | pmid:14569364 |
| McNeil HJ et al. | Novel protease produced by a Pasteurella trehalosi serotype 10 isolate from a pneumonic bighorn sheep: characteristics and potential relevance to protection. | 2003 | Vet. Microbiol. | pmid:12637002 |
| Rainard P et al. | Leucotoxic activities of Staphylococcus aureus strains isolated from cows, ewes, and goats with mastitis: importance of LukM/LukF'-PV leukotoxin. | 2003 | Clin. Diagn. Lab. Immunol. | pmid:12626454 |
| Johansson A et al. | Serum-mediated release of leukotoxin from the cell surface of the periodontal pathogen Actinobacillus actinomycetemcomitans. | 2003 | Eur. J. Oral Sci. | pmid:12786951 |
| Colin DA and Monteil H | Control of the oxidative burst of human neutrophils by staphylococcal leukotoxins. | 2003 | Infect. Immun. | pmid:12819053 |
| Leite F et al. | Prior exposure to Mannheimia haemolytica leukotoxin or LPS enhances beta(2)-integrin expression by bovine neutrophils and augments LKT cytotoxicity. | 2003 | Microb. Pathog. | pmid:12782479 |
| Wernicki A et al. | The influence of transport stress on the humoral immunological response of calves induced by Mannheimia haemolytica leukotoxin. | 2003 | Pol J Vet Sci | pmid:12675467 |
| Frank GH et al. | Effect of intranasal exposure to leukotoxin-deficient Mannheimia haemolytica at the time of arrival at the feedyard on subsequent isolation of M haemolytica from nasal secretions of calves. | 2003 | Am. J. Vet. Res. | pmid:12755298 |
| Cudd L et al. | Mannheimia haemolytica leukotoxin-induced increase in leukotriene B4 production by bovine neutrophils is mediated by a sustained and excessive increase in intracellular calcium concentration. | 2003 | FEMS Microbiol. Lett. | pmid:12855172 |
| Mitchell C et al. | Positive and negative cis-acting regulatory sequences control expression of leukotoxin in Actinobacillus actinomycetemcomitans 652. | 2003 | Infect. Immun. | pmid:14500484 |
| Nalbant A et al. | Induction of T-cell apoptosis by Actinobacillus actinomycetemcomitans mutants with deletion of ltxA and cdtABC genes: possible activity of GroEL-like molecule. | 2003 | Oral Microbiol. Immunol. | pmid:14622339 |
| Kolodrubetz D et al. | Anaerobic regulation of Actinobacillus actinomycetemcomitans leukotoxin transcription is ArcA/FnrA-independent and requires a novel promoter element. | 2003 | Res. Microbiol. | pmid:14596902 |
| Poulsen K et al. | Improved PCR for detection of the highly leukotoxic JP2 clone of Actinobacillus actinomycetemcomitans in subgingival plaque samples. | 2003 | J. Clin. Microbiol. | pmid:14532234 |
| Rudolph KM et al. | Sharing of Pasteurella spp. between free-ranging bighorn sheep and feral goats. | 2003 | J. Wildl. Dis. | pmid:14733287 |
| Henderson B et al. | Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans. | 2003 | Annu. Rev. Microbiol. | pmid:14527274 |