9,10-DiHOME

9,10-dihome is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Maxillary Diseases D008439 3 associated lipids
Goat Diseases D015511 6 associated lipids
Sheep Diseases D012757 10 associated lipids
Cattle Diseases D002418 24 associated lipids
Pulmonary Edema D011654 23 associated lipids
Leukemia D007938 74 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Per page 10 20 50 | Total 29

PubChem Biomolecular Interactions and Pathways

All references with 9,10-DiHOME

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Per page 10 20 50 100 | Total 543
Authors Title Published Journal PubMed Link
Cudd L et al. Mannheimia haemolytica leukotoxin-induced increase in leukotriene B4 production by bovine neutrophils is mediated by a sustained and excessive increase in intracellular calcium concentration. 2003 FEMS Microbiol. Lett. pmid:12855172
Mitchell C et al. Positive and negative cis-acting regulatory sequences control expression of leukotoxin in Actinobacillus actinomycetemcomitans 652. 2003 Infect. Immun. pmid:14500484
Nalbant A et al. Induction of T-cell apoptosis by Actinobacillus actinomycetemcomitans mutants with deletion of ltxA and cdtABC genes: possible activity of GroEL-like molecule. 2003 Oral Microbiol. Immunol. pmid:14622339
Henderson B et al. Molecular pathogenicity of the oral opportunistic pathogen Actinobacillus actinomycetemcomitans. 2003 Annu. Rev. Microbiol. pmid:14527274
Leite F et al. Effect of experimental infection of cattle with bovine herpesvirus-1 (BHV-1) on the ex vivo interaction of bovine leukocytes with Mannheimia (Pasteurella) haemolytica leukotoxin. 2002 Vet. Immunol. Immunopathol. pmid:11825601
Kaplan JB et al. Population structure and genetic diversity of Actinobacillus actinomycetemcomitans strains isolated from localized juvenile periodontitis patients. 2002 J. Clin. Microbiol. pmid:11923328
Narayanan SK et al. Leukotoxins of gram-negative bacteria. 2002 Vet. Microbiol. pmid:11750142
Kato S et al. Outer membrane-like vesicles secreted by Actinobacillus actinomycetemcomitans are enriched in leukotoxin. 2002 Microb. Pathog. pmid:11782116
Davies RL et al. Mosaic structure and molecular evolution of the leukotoxin operon (lktCABD) in Mannheimia (Pasteurella) haemolytica, Mannheimia glucosida, and Pasteurella trehalosi. 2002 J. Bacteriol. pmid:11741868
Leite F et al. Inflammatory cytokines enhance the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood neutrophils in vitro. 2002 Infect. Immun. pmid:12117943
Narayanan S et al. Fusobacterium necrophorum leukotoxin induces activation and apoptosis of bovine leukocytes. 2002 Infect. Immun. pmid:12117974
Kachlany SC et al. Purification of secreted leukotoxin (LtxA) from Actinobacillus actinomycetemcomitans. 2002 Protein Expr. Purif. pmid:12182827
Deshpande MS et al. Bovine CD18 is necessary and sufficient to mediate Mannheimia (Pasteurella) haemolytica leukotoxin-induced cytolysis. 2002 Infect. Immun. pmid:12183553
Okamura S et al. Leukotoxin-activated human pulmonary artery endothelial cell produces nitric oxide and superoxide anion. 2002 Pulm Pharmacol Ther pmid:11969361
Marcatili A et al. p53 and c-myc activation by Pasteurella haemolytica leukotoxin is correlated with bovine mononuclear cells apoptosis. 2002 New Microbiol. pmid:12019726
Murakami Y et al. Inhibitory effect of synthetic histatin 5 on leukotoxin from Actinobacillus actinomycetemcomitans. 2002 Oral Microbiol. Immunol. pmid:12030965
Claesson R et al. Release and activation of matrix metalloproteinase 8 from human neutrophils triggered by the leukotoxin of Actinobacillus actinomycetemcomitans. 2002 J. Periodont. Res. pmid:12366858
Haubek D et al. Attachment loss in Moroccan early onset periodontitis patients and infection with the JP2-type of Actinobacillus actinomycetemcomitans. 2002 J. Clin. Periodontol. pmid:12354092
Saddi-Ortega L et al. Actinobacillus actinomycetemcomitans genetic heterogeneity: amplification of JP2-like ltx promoter pattern correlated with specific arbitrarily primed polymerase chain reaction (AP-PCR) genotypes from human but not marmoset Brazilian isolates. 2002 Can. J. Microbiol. pmid:12224559
Mombelli A et al. Can presence or absence of periodontal pathogens distinguish between subjects with chronic and aggressive periodontitis? A systematic review. 2002 J. Clin. Periodontol. pmid:12787203
Jeyaseelan S et al. Role of Mannheimia haemolytica leukotoxin in the pathogenesis of bovine pneumonic pasteurellosis. 2002 Anim Health Res Rev pmid:12665107
Johansson A et al. Lack of lipoprotein-dependent effects on the cytotoxic interactions of Actinobacillus actinomycetemcomitans leukotoxin with human neutrophils. 2002 APMIS pmid:12645663
Barnes AI et al. Enterobacter cloacae leukotoxin: modulation of reactive oxidant species generated by neutrophils. 2001 Jan-Feb Luminescence pmid:11180656
Ewen C and Baca-Estrada ME Evaluation of interleukin-4 concentration by ELISA is influenced by the consumption of IL-4 by cultured cells. 2001 J. Interferon Cytokine Res. pmid:11177579
Cudd LA et al. Effects of Mannheimia haemolytica leukotoxin on apoptosis and oncosis of bovine neutrophils. 2001 Am. J. Vet. Res. pmid:11197552
Jeyaseelan S et al. Pasteurella (Mannheimia) haemolytica leukotoxin-induced cytolysis of bovine leukocytes: role of arachidonic acid and its regulation. 2001 Microb. Pathog. pmid:11162186
Johansson A et al. Protease inhibitors, the responsible components for the serum-dependent enhancement of Actinobacillus actinomycetemcomitans leukotoxicity. 2001 Eur. J. Oral Sci. pmid:11695755
Fong KP et al. Intra- and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS. 2001 Infect. Immun. pmid:11705942
Inoue T et al. Fermentable-sugar-level-dependent regulation of leukotoxin synthesis in a variably toxic strain of Actinobacillus actinomycetemcomitans. 2001 Microbiology (Reading, Engl.) pmid:11577154
Marciel AM and Highlander SK Use of operon fusions in Mannheimia haemolytica to identify environmental and cis-acting regulators of leukotoxin transcription. 2001 Infect. Immun. pmid:11553565
Fukunaga M and Tsuruda K Actinobacillus actinomycetemcomitans induces lethal effects on the macrophage-like human cell line U937. 2001 Oral Microbiol. Immunol. pmid:11555305
Tan KS et al. Prevalence of Actinobacillus actinomycetemcomitans in an ethnic adult Chinese population. 2001 J. Clin. Periodontol. pmid:11493360
Haubek D et al. Early-onset periodontitis in Morocco is associated with the highly leukotoxic clone of Actinobacillus actinomycetemcomitans. 2001 J. Dent. Res. pmid:11499517
Narayanan SK et al. Cloning, sequencing, and expression of the leukotoxin gene from Fusobacterium necrophorum. 2001 Infect. Immun. pmid:11500416
Yamaguchi N et al. Maintenance of oxidative phosphorylation protects cells from Actinobacillus actinomycetemcomitans leukotoxin-induced apoptosis. 2001 Cell. Microbiol. pmid:11736993
Guthmiller JM et al. Beyond the specific plaque hypothesis: are highly leukotoxic strains of Actinobacillus actinomycetemcomitans a paradigm for periodontal pathogenesis? 2001 Crit. Rev. Oral Biol. Med. pmid:11345522
Podmore M et al. Immunodominant antigens in periodontal disease: a real or illusive concept? 2001 Crit. Rev. Oral Biol. Med. pmid:11345527
Müller HP et al. Intraoral distribution of Actinobacillus actinomycetemcomitans in young adults with minimal periodontal disease. 2001 J. Periodont. Res. pmid:11327078
Schuberth HJ et al. Characterization of leukocytotoxic and superantigen-like factors produced by Staphylococcus aureus isolates from milk of cows with mastitis. 2001 Vet. Microbiol. pmid:11423209
Lafleur RL et al. Lipopolysaccharide enhances cytolysis and inflammatory cytokine induction in bovine alveolar macrophages exposed to Pasteurella (Mannheimia) haemolytica leukotoxin. 2001 Microb. Pathog. pmid:11399141
Prévost G et al. Staphylococcal pore-forming toxins. 2001 Curr. Top. Microbiol. Immunol. pmid:11417122
Zheng J et al. Leukotoxin-diol: a putative toxic mediator involved in acute respiratory distress syndrome. 2001 Am. J. Respir. Cell Mol. Biol. pmid:11694448
Odendaal MW and Du Plessies L The influence of Mannheimia haemolytica A1 seed culture inoculum cell density on the production of leukotoxin in submerged culture supernatant. 2000 Onderstepoort J. Vet. Res. pmid:11131122
Johansson A et al. Inhibition of Actinobacillus actinomycetemcomitans leukotoxicity by bacteria from the subgingival flora. 2000 Oral Microbiol. Immunol. pmid:11154406
Contreras A et al. Frequency of 530-bp deletion in Actinobacillus actinomycetemcomitans leukotoxin promoter region. 2000 Oral Microbiol. Immunol. pmid:11154428
Wang Z et al. [Detecting the level of Actinobacillus actinomycetemcomitans leukotoxin]. 2000 Zhonghua Kou Qiang Yi Xue Za Zhi pmid:11780480
Jeyaseelan S et al. Lymphocyte function-associated antigen 1 is a receptor for Pasteurella haemolytica leukotoxin in bovine leukocytes. 2000 Infect. Immun. pmid:10603370
Paju S et al. Heterogeneity of Actinobacillus actinomycetemcomitans strains in various human infections and relationships between serotype, genotype, and antimicrobial susceptibility. 2000 J. Clin. Microbiol. pmid:10618067
Menestrina G Use of Fourier-transformed infrared spectroscopy for secondary structure determination of staphylococcal pore-forming toxins. 2000 Methods Mol. Biol. pmid:10820719
Argiriadi MA et al. Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. 2000 J. Biol. Chem. pmid:10747889
Uhlich GA et al. FnrP interactions with the Pasteurella haemolytica leukotoxin promoter. 2000 FEMS Microbiol. Lett. pmid:10779715
McClenahan D et al. Role of inflammatory mediators in priming, activation, and deformability of bovine neutrophils. 2000 Am. J. Vet. Res. pmid:10803642
Johansson A et al. Anaerobic neutrophil-dependent killing of Actinobacillus actinomycetemcomitans in relation to the bacterial leukotoxicity. 2000 Eur. J. Oral Sci. pmid:10768727
McClenahan DJ et al. Association among filamentous actin content, CD11b expression, and membrane deformability in stimulated and unstimulated bovine neutrophils. 2000 Am. J. Vet. Res. pmid:10772101
Greene JF et al. Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase. 2000 Chem. Res. Toxicol. pmid:10775319
Korostoff J et al. Perturbation of mitochondrial structure and function plays a central role in Actinobacillus actinomycetemcomitans leukotoxin-induced apoptosis. 2000 Microb. Pathog. pmid:11031121
Kachlany SC et al. Secretion of RTX leukotoxin by Actinobacillus actinomycetemcomitans. 2000 Infect. Immun. pmid:11035711
Bronner S et al. Variable expressions of Staphylococcus aureus bicomponent leucotoxins semiquantified by competitive reverse transcription-PCR. 2000 Appl. Environ. Microbiol. pmid:10966411
Leite F et al. Recombinant bovine interleukin-1beta amplifies the effects of partially purified Pasteurella haemolytica leukotoxin on bovine neutrophils in a beta(2)-integrin-dependent manner. 2000 Infect. Immun. pmid:10992457
Gibb DJ et al. Effect of a trainer cow on health, behavior, and performance of newly weaned beef calves. 2000 J. Anim. Sci. pmid:10907812
Johansson A et al. Polymorphonuclear leukocyte degranulation induced by leukotoxin from Actinobacillus actinomycetemcomitans. 2000 J. Periodont. Res. pmid:10863962
Nakanishi M et al. Leukotoxin, 9,10-epoxy-12-octadecenoate, causes pulmonary vasodilation by stimulation of vascular eNOS and iNOS. 2000 Lung pmid:10871432
Highlander SK et al. Inactivation of Pasteurella (Mannheimia) haemolytica leukotoxin causes partial attenuation of virulence in a calf challenge model. 2000 Infect. Immun. pmid:10858203
Haraszthy VI et al. Evidence for the role of highly leukotoxic Actinobacillus actinomycetemcomitans in the pathogenesis of localized juvenile and other forms of early-onset periodontitis. 2000 J. Periodontol. pmid:10914794
Baca-Estrada ME et al. Effects of IL-12 on immune responses induced by transcutaneous immunization with antigens formulated in a novel lipid-based biphasic delivery system. 2000 Vaccine pmid:10699333
Totani Y et al. Leukotoxin and its diol induce neutrophil chemotaxis through signal transduction different from that of fMLP. 2000 Eur. Respir. J. pmid:10678624
Lear JD et al. Conformational studies of Actinobacillus actinomycetemcomitans leukotoxin: partial denaturation enhances toxicity. 2000 Biochim. Biophys. Acta pmid:10669799
Sun Y et al. Ultrastructural characterization of apoptosis in bovine lymphocytes exposed to Pasteurella haemolytica leukotoxin. 2000 Am. J. Vet. Res. pmid:10630778
Iwase H et al. Effect of cytochrome c on the linoleic acid-degrading activity of porcine leukocyte 12-lipoxygenase. 2000 Free Radic. Biol. Med. pmid:10802222
Jaramillo ML et al. [Mechanisms of pathogenicity and adhesion in Pasteurella haemolytica]. 1999 Apr-Jun Rev. Latinoam. Microbiol. pmid:10932756
Li J and Clinkenbeard KD Lipopolysaccharide complexes with Pasteurella haemolytica leukotoxin. 1999 Infect. Immun. pmid:10338500
Li J et al. Bovine CD18 identified as a species specific receptor for Pasteurella haemolytica leukotoxin. 1999 Vet. Microbiol. pmid:10414364
Wang Z et al. Role of phospholipase D in Pasteurella haemolytica leukotoxin-induced increase in phospholipase A(2) activity in bovine neutrophils. 1999 Infect. Immun. pmid:10417136
Engström PE et al. Oral and systemic immunoglobulin G-subclass antibodies to Actinobacillus actinomycetemcomitans leukotoxin. 1999 Oral Microbiol. Immunol. pmid:10219169
Hsuan SL et al. Pasteurella haemolytica leukotoxin and endotoxin induced cytokine gene expression in bovine alveolar macrophages requires NF-kappaB activation and calcium elevation. 1999 Microb. Pathog. pmid:10222211
Basaraba RJ et al. Actin polymerization enhances Pasteurella haemolytica leukotoxicity. 1999 Vet. Microbiol. pmid:10063536
Sun Y et al. Pasteurella haemolytica leukotoxin induced apoptosis of bovine lymphocytes involves DNA fragmentation. 1999 Vet. Microbiol. pmid:10078599
Cudd L et al. Role of intracellular calcium in Pasteurella haemolytica leukotoxin-induced bovine neutrophil leukotriene B4 production and plasma membrane damage. 1999 FEMS Microbiol. Lett. pmid:10188239
Ambagala TC et al. The leukotoxin of Pasteurella haemolytica binds to beta(2) integrins on bovine leukocytes. 1999 FEMS Microbiol. Lett. pmid:10481101
Lally ET et al. The interaction between RTX toxins and target cells. 1999 Trends Microbiol. pmid:10470043
Ehmke B et al. Clonal infection with Actinobacillus actinomycetemcomitans following periodontal therapy. 1999 J. Dent. Res. pmid:10512386
Lippmann JE et al. Use of the Actinobacillus actinomycetemcomitans leukotoxin promoter to drive expression of the green fluorescent protein in an oral pathogen. 1999 Oral Microbiol. Immunol. pmid:10551160
Macheleidt A et al. Clonal diversity of Actinobacillus actinomycetemcomitans isolates from young adults with minimal periodontal disease. 1999 J. Periodont. Res. pmid:10444741
Sun Y et al. Correlation of Pasteurella haemolytica leukotoxin binding with susceptibility to intoxication of lymphoid cells from various species. 1999 Infect. Immun. pmid:10569736
He T et al. A novel insertion sequence increases the expression of leukotoxicity in Actinobacillus actinomycetemcomitans clinical isolates. 1999 J. Periodontol. pmid:10588488
Macheleidt A et al. Absence of an especially toxic clone among isolates of Actinobacillus actinomycetemcomitans recovered from army recruits. 1999 Clin Oral Investig pmid:10803129
Odendaal MW and Ellis CE The production and evaluation of Pasteurella haemolytica leukotoxin in the supernatant of submerged cultures in fermenters. 1999 Onderstepoort J. Vet. Res. pmid:10689699
Stimers JR et al. Effects of linoleic acid metabolites on electrical activity in adult rat ventricular myocytes. 1999 Biochim. Biophys. Acta pmid:10366778
Lépine G et al. Epithelial cell invasion by Actinobacillus actinomycetemcomitans strains from restriction fragment-length polymorphism groups associated with juvenile periodontitis or carrier status. 1998 Oral Microbiol. Immunol. pmid:9872109
Confer AW et al. Duration of serum antibody responses following vaccination and revaccination of cattle with non-living commercial Pasteurella haemolytica vaccines. 1998 Vaccine pmid:9796051
Hodgins DC and Shewen PE Serologic responses of young colostrum fed dairy calves to antigens of Pasteurella haemolytica A1. 1998 Vaccine pmid:9796059
Bueno LC et al. Relationship between conversion of localized juvenile periodontitis-susceptible children from health to disease and Actinobacillus actinomycetemcomitans leukotoxin promoter structure. 1998 J. Periodontol. pmid:9776028
Schenkein HA Etiology of localized juvenile periodontitis. 1998 J. Periodontol. pmid:9776037
Wang JF et al. Molecular and biochemical mechanisms of Pasteurella haemolytica leukotoxin-induced cell death. 1998 Microb. Pathog. pmid:9895270
Veit HP et al. Toxin production by Pasteurella granulomatis. 1998 Ann. N. Y. Acad. Sci. pmid:9668517
Mombelli A et al. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in young Chinese adults. 1998 Oral Microbiol. Immunol. pmid:10093538
Mosier DA et al. Comparison of serologic and protective responses induced by two Pasteurella vaccines. 1998 Can. J. Vet. Res. pmid:9684046
Sun Y and Clinkenbeard KD Serum-free culture of Pasteurella haemolytica optimized for leukotoxin production. 1998 Am. J. Vet. Res. pmid:9659550
Wang Z et al. Pasteurella haemolytica leukotoxin-induced increase in phospholipase A2 activity in bovine neutrophils. 1998 Infect. Immun. pmid:9573065
Cheryk LA et al. Alterations in bovine platelet function and acute phase proteins induced by Pasteurella haemolytica A1. 1998 Can. J. Vet. Res. pmid:9442932

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