9,10-DiHOME

9,10-dihome is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Maxillary Diseases D008439 3 associated lipids
Goat Diseases D015511 6 associated lipids
Sheep Diseases D012757 10 associated lipids
Cattle Diseases D002418 24 associated lipids
Pulmonary Edema D011654 23 associated lipids
Leukemia D007938 74 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Per page 10 20 50 | Total 29

PubChem Biomolecular Interactions and Pathways

All references with 9,10-DiHOME

Download all related citations
Per page 10 20 50 100 | Total 543
Authors Title Published Journal PubMed Link
Sun DB et al. Identification of three immunodominant regions on leukotoxin protein of Fusobacterium necrophorum. 2009 Vet. Res. Commun. pmid:19449113
Balashova NV et al. Aggregatibacter actinomycetemcomitans LtxC is required for leukotoxin activity and initial interaction between toxin and host cells. 2009 Gene pmid:19450669
Larsen J et al. Evolution of the leukotoxin promoter in genus Mannheimia. 2009 BMC Evol. Biol. pmid:19480674
Ayalew S et al. Intranasal vaccination of calves with Mannheimia haemolytica chimeric protein containing the major surface epitope of outer membrane lipoprotein PlpE, the neutralizing epitope of leukotoxin, and cholera toxin subunit B. 2009 Vet. Immunol. Immunopathol. pmid:19581005
Aberg CH et al. Presence of Aggregatibacter actinomycetemcomitans in young individuals: a 16-year clinical and microbiological follow-up study. 2009 J. Clin. Periodontol. pmid:19678862
Kawamoto D et al. Genetic diversity and toxic activity of Aggregatibacter actinomycetemcomitans isolates. 2009 Oral Microbiol. Immunol. pmid:19832802
Kim TS et al. Serotypes of Aggregatibacter actinomycetemcomitans in patients with different ethnic backgrounds. 2009 J. Periodontol. pmid:19961385
Fett T et al. Mannheimia haemolytica leukotoxin-induced cytolysis of caprine (Capra hircus) leukocytes is mediated by the CD18 subunit of beta2-integrins. 2008 Nov-Dec Microb. Pathog. pmid:18775487
Isaza MP et al. Screen for leukotoxin mutants in Aggregatibacter actinomycetemcomitans: genes of the phosphotransferase system are required for leukotoxin biosynthesis. 2008 Infect. Immun. pmid:18541661
Venketaraman V et al. Both leukotoxin and poly-N-acetylglucosamine surface polysaccharide protect Aggregatibacter actinomycetemcomitans cells from macrophage killing. 2008 Microb. Pathog. pmid:18573331
Ayalew S et al. Mannheimia haemolytica chimeric protein vaccine composed of the major surface-exposed epitope of outer membrane lipoprotein PlpE and the neutralizing epitope of leukotoxin. 2008 Vaccine pmid:18675308
Dassanayake RP et al. Bighorn sheep beta2-integrin LFA-1 serves as a receptor for Mannheimia haemolytica leukotoxin. 2008 J. Wildl. Dis. pmid:18689665
Takashima E and Konishi K Characterization of a quinol peroxidase mutant in Aggregatibacter actinomycetemcomitans. 2008 FEMS Microbiol. Lett. pmid:18616592
Gallant CV et al. Membrane morphology and leukotoxin secretion are associated with a novel membrane protein of Aggregatibacter actinomycetemcomitans. 2008 J. Bacteriol. pmid:18621903
Baum MS Destroying malignant white cells. 2008 J N J Dent Assoc pmid:18557488
Atapattu DN et al. Dynamin-2-dependent targeting of mannheimia haemolytica leukotoxin to mitochondrial cyclophilin D in bovine lymphoblastoid cells. 2008 Infect. Immun. pmid:18765728
Wang D et al. Molecular mimicry of Aggregatibacter actinomycetemcomitans with beta2 glycoprotein I. 2008 Oral Microbiol. Immunol. pmid:18793363
Harris TR et al. Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules. 2008 Arch. Biochem. Biophys. pmid:18267101
Wernicki A et al. Comparison of immunogenic properties of native and inactivated Mannheimia haemolytica Lkt in calves. 2008 Pol J Vet Sci pmid:18683535
Kelk P et al. IL-1beta secretion induced by Aggregatibacter (Actinobacillus) actinomycetemcomitans is mainly caused by the leukotoxin. 2008 Int. J. Med. Microbiol. pmid:17888725
Tadepalli S et al. Leukotoxin operon and differential expressions of the leukotoxin gene in bovine Fusobacterium necrophorum subspecies. 2008 Anaerobe pmid:17988899
McClenahan D et al. Effects of lipopolysaccharide and Mannheimia haemolytica leukotoxin on bovine lung microvascular endothelial cells and alveolar epithelial cells. 2008 Clin. Vaccine Immunol. pmid:18032592
Schaeffer LM et al. Induction of Aggregatibacter actinomycetemcomitans leukotoxin expression by IS1301 and orfA. 2008 Microbiology (Reading, Engl.) pmid:18227257
Tadepalli S et al. Human Fusobacterium necrophorum strains have a leukotoxin gene and exhibit leukotoxic activity. 2008 J. Med. Microbiol. pmid:18201990
Roblin P et al. A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins. 2008 Proteins pmid:18214982
du Preez JC et al. Kinetics of growth and leukotoxin production by Mannheimia haemolytica in continuous culture. 2008 J. Ind. Microbiol. Biotechnol. pmid:18283506
Lawrence PK et al. beta(2) integrin Mac-1 is a receptor for Mannheimia haemolytica leukotoxin on bovine and ovine leukocytes. 2008 Vet. Immunol. Immunopathol. pmid:18262657
Rainard P Staphylococcus aureus leucotoxin LukM/F' is secreted and stimulates neutralising antibody response in the course of intramammary infection. 2007 Sep-Oct Vet. Res. pmid:17583665
Dassanayake RP et al. Mannheimia haemolytica leukotoxin-induced cytolysis of ovine (Ovis aries) leukocytes is mediated by CD18, the beta subunit of beta2-integrins. 2007 May-Jun Microb. Pathog. pmid:17368825
Kieba IR et al. Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. 2007 Cell. Microbiol. pmid:17587330
Crosby JA and Kachlany SC TdeA, a TolC-like protein required for toxin and drug export in Aggregatibacter (Actinobacillus) actinomycetemcomitans. 2007 Gene pmid:17116373
Larsen J et al. Analysis of gene order data supports vertical inheritance of the leukotoxin operon and genome rearrangements in the 5' flanking region in genus Mannheimia. 2007 BMC Evol. Biol. pmid:17915007
Kanangat S et al. Modulation of virulence gene expression in Staphylococcus aureus by interleukin-1beta: novel implications in bacterial pathogenesis. 2007 Microbes Infect. pmid:17307379
Dileepan T et al. Integrin-EGF-3 domain of bovine CD18 is critical for Mannheimia haemolytica leukotoxin species-specific susceptibility. 2007 FEMS Microbiol. Lett. pmid:17590223
Lawrence PK et al. Transfection of non-susceptible cells with Ovis aries recombinant lymphocyte function-associated antigen 1 renders susceptibility to Mannheimia haemolytica leukotoxin. 2007 Vet. Microbiol. pmid:17590539
van Rensburg E and du Preez JC Effect of pH, temperature and nutrient limitations on growth and leukotoxin production by Mannheimia haemolytica in batch and continuous culture. 2007 J. Appl. Microbiol. pmid:17448162
Liu W et al. Mannheimia (Pasteurella) haemolytica leukotoxin utilizes CD18 as its receptor on bighorn sheep leukocytes. 2007 J. Wildl. Dis. pmid:17347395
Atapattu DN and Czuprynski CJ Mannheimia haemolytica leukotoxin binds to lipid rafts in bovine lymphoblastoid cells and is internalized in a dynamin-2- and clathrin-dependent manner. 2007 Infect. Immun. pmid:17682044
Dileepan T et al. Human CD18 is the functional receptor for Aggregatibacter actinomycetemcomitans leukotoxin. 2007 Infect. Immun. pmid:17635865
Balashova NV et al. Interaction between leukotoxin and Cu,Zn superoxide dismutase in Aggregatibacter actinomycetemcomitans. 2007 Infect. Immun. pmid:17635874
Rice JA et al. Mannheimia haemolytica and bovine respiratory disease. 2007 Anim Health Res Rev pmid:18218156
Dassanayake RP et al. Monomeric expression of bovine beta2-integrin subunits reveals their role in Mannheimia haemolytica leukotoxin-induced biological effects. 2007 Infect. Immun. pmid:17698568
Larsen J et al. Evidence for vertical inheritance and loss of the leukotoxin operon in genus Mannheimia. 2007 J. Mol. Evol. pmid:17437147
de Haar SF et al. Role of polymorphonuclear leukocyte-derived serine proteinases in defense against Actinobacillus actinomycetemcomitans. 2006 Infect. Immun. pmid:16926422
Wu H et al. Inactivation of DNA adenine methyltransferase alters virulence factors in Actinobacillus actinomycetemcomitans. 2006 Oral Microbiol. Immunol. pmid:16842508
Confer AW et al. Recombinant Mannheimia haemolytica serotype 1 outer membrane protein PlpE enhances commercial M. haemolytica vaccine-induced resistance against serotype 6 challenge. 2006 Vaccine pmid:16430995
Van Rensburg E et al. Quantification of Mannheimia haemolytica leukotoxin by indirect ELISA. 2006 Onderstepoort J. Vet. Res. pmid:17283723
Permpanich P et al. Resistance of fluorescent-labelled Actinobacillus actinomycetemcomitans strains to phagocytosis and killing by human neutrophils. 2006 Cell. Microbiol. pmid:16367867
Prado ME et al. Maternally and naturally acquired antibodies to Mannheimia haemolytica and Pasteurella multocida in beef calves. 2006 Vet. Immunol. Immunopathol. pmid:16386312
Zhang F et al. The two major subspecies of Fusobacterium necrophorum have distinct leukotoxin operon promoter regions. 2006 Vet. Microbiol. pmid:16303263

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