9,10-DiHOME

9,10-dihome is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Maxillary Diseases D008439 3 associated lipids
Goat Diseases D015511 6 associated lipids
Sheep Diseases D012757 10 associated lipids
Cattle Diseases D002418 24 associated lipids
Pulmonary Edema D011654 23 associated lipids
Leukemia D007938 74 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Per page 10 20 50 | Total 29

PubChem Biomolecular Interactions and Pathways

All references with 9,10-DiHOME

Download all related citations
Per page 10 20 50 100 | Total 543
Authors Title Published Journal PubMed Link
Prado ME et al. Maternally and naturally acquired antibodies to Mannheimia haemolytica and Pasteurella multocida in beef calves. 2006 Vet. Immunol. Immunopathol. pmid:16386312
Confer AW et al. Recombinant Mannheimia haemolytica serotype 1 outer membrane protein PlpE enhances commercial M. haemolytica vaccine-induced resistance against serotype 6 challenge. 2006 Vaccine pmid:16430995
Joubert O et al. Engineered covalent leucotoxin heterodimers form functional pores: insights into S-F interactions. 2006 Biochem. J. pmid:16494579
Balashova NV et al. Leukotoxin confers beta-hemolytic activity to Actinobacillus actinomycetemcomitans. 2006 Infect. Immun. pmid:16552030
Gatto NT et al. Lung lesions in SCID-bo and SCID-bg mice after intratracheal inoculation with wild-type or leucotoxin-deficient mutant strains of Mannheimia haemolytica serotype 1. 2006 J. Comp. Pathol. pmid:16712865
Orrù G et al. Usefulness of real time PCR for the differentiation and quantification of 652 and JP2 Actinobacillus actinomycetemcomitans genotypes in dental plaque and saliva. 2006 BMC Infect. Dis. pmid:16772039
Fong KP et al. Actinobacillus actinomycetemcomitans leukotoxin requires lipid microdomains for target cell cytotoxicity. 2006 Cell. Microbiol. pmid:16827908
Wu H et al. Inactivation of DNA adenine methyltransferase alters virulence factors in Actinobacillus actinomycetemcomitans. 2006 Oral Microbiol. Immunol. pmid:16842508
Haubek D et al. Aggressive periodontitis in a 16-year-old Ghanaian adolescent, the original source of Actinobacillus actinomycetemcomitans strain HK1651 - a 10-year follow up. 2006 Int J Paediatr Dent pmid:16879336
de Haar SF et al. Role of polymorphonuclear leukocyte-derived serine proteinases in defense against Actinobacillus actinomycetemcomitans. 2006 Infect. Immun. pmid:16926422
Balashova NV et al. Regulation of Aggregatibacter (Actinobacillus) actinomycetemcomitans leukotoxin secretion by iron. 2006 J. Bacteriol. pmid:17041062
Ebersole JL et al. Molecular approaches to leucotoxin as a virulence component in Actinobacillus actinomycetemcomitans. 1990 Arch. Oral Biol. pmid:1708231
Crosby JA and Kachlany SC TdeA, a TolC-like protein required for toxin and drug export in Aggregatibacter (Actinobacillus) actinomycetemcomitans. 2007 Gene pmid:17116373
Van Rensburg E et al. Quantification of Mannheimia haemolytica leukotoxin by indirect ELISA. 2006 Onderstepoort J. Vet. Res. pmid:17283723
McWhinney DR et al. Separable domains define target cell specificities of an RTX hemolysin from Actinobacillus pleuropneumoniae. 1992 J. Bacteriol. pmid:1729215
Hughes HP et al. Molecular chimerization of Pasteurella haemolytica leukotoxin to interleukin-2: effects on cytokine and antigen function. 1992 Infect. Immun. pmid:1730490
Kanangat S et al. Modulation of virulence gene expression in Staphylococcus aureus by interleukin-1beta: novel implications in bacterial pathogenesis. 2007 Microbes Infect. pmid:17307379
Liu W et al. Mannheimia (Pasteurella) haemolytica leukotoxin utilizes CD18 as its receptor on bighorn sheep leukocytes. 2007 J. Wildl. Dis. pmid:17347395
Dassanayake RP et al. Mannheimia haemolytica leukotoxin-induced cytolysis of ovine (Ovis aries) leukocytes is mediated by CD18, the beta subunit of beta2-integrins. 2007 May-Jun Microb. Pathog. pmid:17368825
Larsen J et al. Evidence for vertical inheritance and loss of the leukotoxin operon in genus Mannheimia. 2007 J. Mol. Evol. pmid:17437147
van Rensburg E and du Preez JC Effect of pH, temperature and nutrient limitations on growth and leukotoxin production by Mannheimia haemolytica in batch and continuous culture. 2007 J. Appl. Microbiol. pmid:17448162
Gentry MJ and Srikumaran S Neutralizing monoclonal antibodies to Pasteurella haemolytica leukotoxin affinity-purify the toxin from crude culture supernatants. 1991 Microb. Pathog. pmid:1753879
Rainard P Staphylococcus aureus leucotoxin LukM/F' is secreted and stimulates neutralising antibody response in the course of intramammary infection. 2007 Sep-Oct Vet. Res. pmid:17583665
Kieba IR et al. Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity. 2007 Cell. Microbiol. pmid:17587330
Dileepan T et al. Integrin-EGF-3 domain of bovine CD18 is critical for Mannheimia haemolytica leukotoxin species-specific susceptibility. 2007 FEMS Microbiol. Lett. pmid:17590223
Lawrence PK et al. Transfection of non-susceptible cells with Ovis aries recombinant lymphocyte function-associated antigen 1 renders susceptibility to Mannheimia haemolytica leukotoxin. 2007 Vet. Microbiol. pmid:17590539
Dileepan T et al. Human CD18 is the functional receptor for Aggregatibacter actinomycetemcomitans leukotoxin. 2007 Infect. Immun. pmid:17635865
Balashova NV et al. Interaction between leukotoxin and Cu,Zn superoxide dismutase in Aggregatibacter actinomycetemcomitans. 2007 Infect. Immun. pmid:17635874
Atapattu DN and Czuprynski CJ Mannheimia haemolytica leukotoxin binds to lipid rafts in bovine lymphoblastoid cells and is internalized in a dynamin-2- and clathrin-dependent manner. 2007 Infect. Immun. pmid:17682044
Dassanayake RP et al. Monomeric expression of bovine beta2-integrin subunits reveals their role in Mannheimia haemolytica leukotoxin-induced biological effects. 2007 Infect. Immun. pmid:17698568
Kelk P et al. IL-1beta secretion induced by Aggregatibacter (Actinobacillus) actinomycetemcomitans is mainly caused by the leukotoxin. 2008 Int. J. Med. Microbiol. pmid:17888725
Larsen J et al. Analysis of gene order data supports vertical inheritance of the leukotoxin operon and genome rearrangements in the 5' flanking region in genus Mannheimia. 2007 BMC Evol. Biol. pmid:17915007
Tadepalli S et al. Leukotoxin operon and differential expressions of the leukotoxin gene in bovine Fusobacterium necrophorum subspecies. 2008 Anaerobe pmid:17988899
McClenahan D et al. Effects of lipopolysaccharide and Mannheimia haemolytica leukotoxin on bovine lung microvascular endothelial cells and alveolar epithelial cells. 2008 Clin. Vaccine Immunol. pmid:18032592
Tadepalli S et al. Human Fusobacterium necrophorum strains have a leukotoxin gene and exhibit leukotoxic activity. 2008 J. Med. Microbiol. pmid:18201990
Roblin P et al. A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of beta-barrel pore-forming toxins. 2008 Proteins pmid:18214982
Rice JA et al. Mannheimia haemolytica and bovine respiratory disease. 2007 Anim Health Res Rev pmid:18218156
Schaeffer LM et al. Induction of Aggregatibacter actinomycetemcomitans leukotoxin expression by IS1301 and orfA. 2008 Microbiology (Reading, Engl.) pmid:18227257
Lawrence PK et al. beta(2) integrin Mac-1 is a receptor for Mannheimia haemolytica leukotoxin on bovine and ovine leukocytes. 2008 Vet. Immunol. Immunopathol. pmid:18262657
Harris TR et al. Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules. 2008 Arch. Biochem. Biophys. pmid:18267101
du Preez JC et al. Kinetics of growth and leukotoxin production by Mannheimia haemolytica in continuous culture. 2008 J. Ind. Microbiol. Biotechnol. pmid:18283506
Taichman NS et al. Membranolytic activity of Actinobacillus actinomycetemcomitans leukotoxin. 1991 J. Periodont. Res. pmid:1831848
Lally ET et al. Actinobacillus actinomycetemcomitans leukotoxin is a calcium-binding protein. 1991 J. Periodont. Res. pmid:1831850
Redmond MJ et al. Rotavirus particles function as immunological carriers for the delivery of peptides from infectious agents and endogenous proteins. 1991 Mol. Immunol. pmid:1850113
Isaza MP et al. Screen for leukotoxin mutants in Aggregatibacter actinomycetemcomitans: genes of the phosphotransferase system are required for leukotoxin biosynthesis. 2008 Infect. Immun. pmid:18541661
Baum MS Destroying malignant white cells. 2008 J N J Dent Assoc pmid:18557488
Venketaraman V et al. Both leukotoxin and poly-N-acetylglucosamine surface polysaccharide protect Aggregatibacter actinomycetemcomitans cells from macrophage killing. 2008 Microb. Pathog. pmid:18573331
Takashima E and Konishi K Characterization of a quinol peroxidase mutant in Aggregatibacter actinomycetemcomitans. 2008 FEMS Microbiol. Lett. pmid:18616592
Gallant CV et al. Membrane morphology and leukotoxin secretion are associated with a novel membrane protein of Aggregatibacter actinomycetemcomitans. 2008 J. Bacteriol. pmid:18621903
Ayalew S et al. Mannheimia haemolytica chimeric protein vaccine composed of the major surface-exposed epitope of outer membrane lipoprotein PlpE and the neutralizing epitope of leukotoxin. 2008 Vaccine pmid:18675308

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