9,10-DiHOME

9,10-dihome is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2500 references associated with 9,10-DiHOME in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 9,10-DiHOME

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 9,10-DiHOME

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Maxillary Diseases D008439 3 associated lipids
Goat Diseases D015511 6 associated lipids
Sheep Diseases D012757 10 associated lipids
Cattle Diseases D002418 24 associated lipids
Pulmonary Edema D011654 23 associated lipids
Leukemia D007938 74 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Per page 10 20 50 | Total 29

PubChem Biomolecular Interactions and Pathways

All references with 9,10-DiHOME

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Per page 10 20 50 100 | Total 543
Authors Title Published Journal PubMed Link
Gentry MJ et al. Effect of repeated in vitro transfer of Pasteurella haemolytica A1 on encapsulation, leukotoxin production, and virulence. 1987 J. Clin. Microbiol. pmid:3793866
Sugiyama S et al. Leukotoxin, 9, 10-epoxy-12-octadecenoate, causes cardiac failure in dogs. 1987 Life Sci. pmid:3796222
Zambon JJ Actinobacillus actinomycetemcomitans in human periodontal disease. 1985 J. Clin. Periodontol. pmid:3882766
Lo RY et al. Cloning and expression of the leukotoxin gene of Pasteurella haemolytica A1 in Escherichia coli K-12. 1985 Infect. Immun. pmid:3905610
Rotstein OD et al. A Bacteroides by-product inhibits human polymorphonuclear leukocyte function. 1986 Arch Surg pmid:3942502
Chang YF and Renshaw HW Pasteurella haemolytica leukotoxin: comparison of 51chromium-release, trypan blue dye exclusion, and luminol-dependent chemiluminescence-inhibition assays for sensitivity in detecting leukotoxin activity. 1986 Am. J. Vet. Res. pmid:3946893
Chang YF et al. Pasteurella haemolytica leukotoxin: chemiluminescent responses of peripheral blood leukocytes from several different mammalian species to leukotoxin- and opsonin-treated living and killed Pasteurella haemolytica and Staphylococcus aureus. 1986 Am. J. Vet. Res. pmid:3946910
Ozawa T et al. Biosynthesis of leukotoxin, 9,10-epoxy-12 octadecenoate, by leukocytes in lung lavages of rat after exposure to hyperoxia. 1986 Biochem. Biophys. Res. Commun. pmid:3947358
Chang YF et al. Pasteurella haemolytica leukotoxin: physicochemical characteristics and susceptibility of leukotoxin to enzymatic treatment. 1986 Am. J. Vet. Res. pmid:3963575
DiRienzo JM et al. Monoclonal antibodies to leukotoxin of Actinobacillus actinomycetemcomitans. 1985 Infect. Immun. pmid:3965404
Moore RN et al. Antileukotoxin antibody produced in the bovine lung after aerosol exposure to viable Pasteurella haemolytica. 1985 Am. J. Vet. Res. pmid:4051300
Baehni PC et al. Leukotoxic activity in different strains of the bacterium Actinobacillus actinomycetemcomitans isolated from juvenile periodontitis in man. 1981 Arch. Oral Biol. pmid:6172101
Ebersole JL et al. Human immune responses to oral microorganisms. II. Serum antibody responses to antigens from Actinobacillus actinomycetemcomitans and the correlation with localized juvenile periodontitis. 1983 J. Clin. Immunol. pmid:6197423
Taichman NS et al. Cytopathic effects of Actinobacillus actinomycetemcomitans on monkey blood leukocytes. 1984 J. Periodont. Res. pmid:6231364
Spitznagel JK Microbial interactions with neutrophils. 1983 Sep-Oct Rev. Infect. Dis. pmid:6314473
Tsai CC et al. Extraction and isolation of a leukotoxin from Actinobacillus actinomycetemcomitans with polymyxin B. 1984 Infect. Immun. pmid:6319288
Pruett TL et al. Mechanism of the adjuvant effect of hemoglobin in experimental peritonitis: VIII. A leukotoxin is produced by Escherichia coli metabolism in hemoglobin. 1984 Surgery pmid:6379961
McArthur WP et al. Leukotoxic effects of Actinobacillus actinomycetemcomitans. Modulation by serum components. 1981 J. Periodont. Res. pmid:6453979
Zambon JJ et al. Studies of leukotoxin from Actinobacillus actinomycetemcomitans using the promyelocytic HL-60 cell line. 1983 Infect. Immun. pmid:6572616
Slots J and Genco RJ Black-pigmented Bacteroides species, Capnocytophaga species, and Actinobacillus actinomycetemcomitans in human periodontal disease: virulence factors in colonization, survival, and tissue destruction. 1984 J. Dent. Res. pmid:6583243
Sullivan GW and Mandell GL Role of neutrophil degranulation in streptococcal leukotoxicity. 1981 Infect. Immun. pmid:7021425
Stevens RH et al. Characterization of an inducible bacteriophage from a leukotoxic strain of Actinobacillus actinomycetemcomitans. 1982 Infect. Immun. pmid:7054125
Scanlan CM et al. Comparative in vitro leukotoxin production of three bovine strains of Fusobacterium necrophorum. 1982 Am. J. Vet. Res. pmid:7103216
Ginsburg I et al. Phospholipids inhibit cytotoxic effects of Actinobacillus actinomycetemcomitans leukotoxin on human polymorphonuclear leukocytes. 1982 Inflammation pmid:7160873
Taichman NS and Wilton JM Leukotoxicity of an extract from Actinobacillus actinomycetemcomitans for human gingival polymorphonuclear leukocytes. 1981 Inflammation pmid:7228351
Yoo HS et al. Purified Pasteurella haemolytica leukotoxin induces expression of inflammatory cytokines from bovine alveolar macrophages. 1995 Microb. Pathog. pmid:7476090
Guthmiller JM et al. Mutational analysis of the putative leukotoxin transport genes in Actinobacillus actinomycetemcomitans. 1995 Microb. Pathog. pmid:7476096
DeSilva RT et al. Partial characterization of the leukotoxin of Pasteurella haemolytica-like bacteria isolated from swine enteritis. 1995 Vet. Microbiol. pmid:7483245
Iwase H et al. pH dependent alterations of monoepoxides and monochlorohydrins of linoleic acid, and their existence in vivo. 1995 Biochem. Biophys. Res. Commun. pmid:7488065
Adusu TE et al. Pasteurella haemolytica leukotoxin induces histamine release from bovine pulmonary mast cells. 1994 Can. J. Vet. Res. pmid:7511483
Ishizaki T et al. Leukotoxin, 9,10-epoxy-12-octadecenoate causes edematous lung injury via activation of vascular nitric oxide synthase. 1995 Am. J. Physiol. pmid:7543250
Lear JD et al. Actinobacillus actinomycetemcomitans leukotoxin forms large conductance, voltage-gated ion channels when incorporated into planar lipid bilayers. 1995 Biochim. Biophys. Acta pmid:7544624
Kato S et al. Evidence for apoptosis of murine macrophages by Actinobacillus actinomycetemcomitans infection. 1995 Infect. Immun. pmid:7558299
Stabholz A et al. Occurrence of Actinobacillus actinomycetemcomitans and anti-leukotoxin antibodies in some members of an extended family affected by Papillon-Lefèvre syndrome. 1995 J. Periodontol. pmid:7562358
Sakai T et al. Leukotoxin, 9,10-epoxy-12-octadecenoate inhibits mitochondrial respiration of isolated perfused rat lung. 1995 Am. J. Physiol. pmid:7573465
Chang YF et al. Sequence analysis of leukotoxin secretion determinants from a Pasteurella haemolytica-like organism. 1995 DNA Seq. pmid:7579583
Murphy GL et al. Hemolytic activity of the Pasteurella haemolytica leukotoxin. 1995 Infect. Immun. pmid:7622250
Stevens P and Czuprynski C Dissociation of cytolysis and monokine release by bovine mononuclear phagocytes incubated with Pasteurella haemolytica partially purified leukotoxin and lipopolysaccharide. 1995 Can. J. Vet. Res. pmid:7648522
Spitznagel J et al. The regulation of leukotoxin production in Actinobacillus actinomycetemcomitans strain JP2. 1995 Adv. Dent. Res. pmid:7669214
Zhang F et al. Secretion and circular dichroism analysis of the C-terminal signal peptides of HlyA and LktA. 1995 Biochemistry pmid:7703231
Haubek D et al. Evidence for absence in northern Europe of especially virulent clonal types of Actinobacillus actinomycetemcomitans. 1995 J. Clin. Microbiol. pmid:7714199
Sweeney SJ et al. Comparative leukotoxicities of Pasteurella haemolytica isolates from domestic sheep and free-ranging bighorn sheep (Ovis canadensis). 1994 J. Wildl. Dis. pmid:7760481
Loftus A and Delisle AL Inducible bacteriophages of Actinobacillus actinomycetemcomitans. 1995 Curr. Microbiol. pmid:7766161
Yin Y et al. Structural analysis and comparison of the C-terminal transport signal domains of hemolysin A and leukotoxin A. 1995 FEBS Lett. pmid:7789505
Kolodrubetz D et al. Directed genomic integration in Actinobacillus actinomycetemcomitans: generation of defined leukotoxin-negative mutants. 1995 Infect. Immun. pmid:7790100
Sjödin B et al. Periodontal and systemic findings in children with marginal bone loss in the primary dentition. 1995 J. Clin. Periodontol. pmid:7790527
Mdurvwa EG and Brunner CJ Bovine neutrophil activation by culture fluid from Pasteurella haemolytica serotypes A1 and A11. 1994 Vet. Microbiol. pmid:7801531
Waurzyniak BJ et al. Enhancement of Pasteurella haemolytica leukotoxic activity by bovine serum albumin. 1994 Am. J. Vet. Res. pmid:7802395
Nagao M et al. Production of monoclonal antibody reactive with leukotoxin and its immunohistochemical application. 1994 Forensic Sci. Int. pmid:7813996
Ishizaki T et al. Leukotoxin, 9,10-epoxy-12-octadecenoate causes pulmonary vasodilation in rats. 1995 Am. J. Physiol. pmid:7840218
Chidambaram M et al. Isolation of Pasteurella haemolytica leukotoxin mutants. 1995 Infect. Immun. pmid:7868223
Petras SF et al. Antigenic and virulence properties of Pasteurella haemolytica leukotoxin mutants. 1995 Infect. Immun. pmid:7868224
Tan ZL et al. Purification and quantification of Fusobacterium necrophorum leukotoxin by using monoclonal antibodies. 1994 Vet. Microbiol. pmid:7886927
Lin CY et al. Rapid and specific detection of the leukotoxin sequences of Actinobacillus actinomycetemcomitans from periodontal pockets by the polymerase chain reaction. 1994 J. Formos. Med. Assoc. pmid:7914769
Poulsen K et al. Population structure of Actinobacillus actinomycetemcomitans: a framework for studies of disease-associated properties. 1994 Microbiology (Reading, Engl.) pmid:7921255
Clinkenbeard KD et al. Pasteurella haemolytica leukotoxin-induced synthesis of eicosanoids by bovine neutrophils in vitro. 1994 J. Leukoc. Biol. pmid:7964171
Gatewood DM et al. Growth-condition dependent expression of Pasteurella haemolytica A1 outer membrane proteins, capsule, and leukotoxin. 1994 Vet. Microbiol. pmid:7975148
Lally ET et al. Identification and immunological characterization of the domain of Actinobacillus actinomycetemcomitans leukotoxin that determines its specificity for human target cells. 1994 J. Biol. Chem. pmid:7983074
Tan ZL et al. Biological and biochemical characterization of Fusobacterium necrophorum leukotoxin. 1994 Am. J. Vet. Res. pmid:8017697
Tan ZL et al. Biochemical and biological characterization of ruminal Fusobacterium necrophorum. 1994 FEMS Microbiol. Lett. pmid:8056298
Zhang WD et al. Intercellular localization of leukotoxin (9:10-epoxy-12-octadecenoic acid) in lungs in rats by an immunoelectron microscopy. 1994 Nihon Hoigaku Zasshi pmid:8065066
Ricketts AP et al. A leukotoxin nonproducing mutant of Pasteurella haemolytica. Phagocytosis and killing by bovine polymorphonucleocytes. 1994 Ann. N. Y. Acad. Sci. pmid:8080187
Tan ZL et al. Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. 1994 J. Anim. Sci. pmid:8157537
Hughes HP et al. Regulation of major histocompatibility complex class II expression by Pasteurella haemolytica leukotoxin. 1994 Infect. Immun. pmid:8168921
Highlander SK and Weinstock GM Static DNA bending and protein interactions within the Pasteurella haemolytica leukotoxin promoter region: development of an activation model for leukotoxin transcriptional control. 1994 DNA Cell Biol. pmid:8179822
Burrows LL et al. Molecular analysis of the leukotoxin determinants from Pasteurella haemolytica serotypes 1 to 16. 1993 Infect. Immun. pmid:8225575
Engström PE et al. Specificity and levels of oral and systemic antibodies to Actinobacillus actinomycetemcomitans. 1993 J. Clin. Periodontol. pmid:8276986
Brogan JM et al. Regulation of Actinobacillus actinomycetemcomitans leukotoxin expression: analysis of the promoter regions of leukotoxic and minimally leukotoxic strains. 1994 Infect. Immun. pmid:8300209
Woldehiwet Z et al. The effects of tick-borne fever on the susceptibility of ovine polymorphonuclear cells to P. haemolytica cytotoxin. 1993 J. Comp. Pathol. pmid:8300918
Shenker BJ et al. Flow cytometric analysis of the cytotoxic effects of Actinobacillus actinomycetemcomitans leukotoxin on human natural killer cells. 1994 J. Leukoc. Biol. pmid:8301211
Conlon JA and Shewen PE Clinical and serological evaluation of a Pasteurella haemolytica A1 capsular polysaccharide vaccine. 1993 Vaccine pmid:8342324
Tønjum T and Haas R Identification of Actinobacillus actinomycetemcomitans by leukotoxin gene-specific hybridization and polymerase chain reaction assays. 1993 J. Clin. Microbiol. pmid:8349764
Goncharoff P et al. Identification of Actinobacillus actinomycetemcomitans: polymerase chain reaction amplification of lktA-specific sequences. 1993 Oral Microbiol. Immunol. pmid:8355983
Bélanger A et al. Effects of Pasteurella haemolytica culture supernate on bovine tracheal smooth muscle. 1993 Can. J. Vet. Res. pmid:8358681
Highlander SK et al. Expression of the Pasteurella haemolytica leukotoxin is inhibited by a locus that encodes an ATP-binding cassette homolog. 1993 Infect. Immun. pmid:8359916
Maheswaran SK et al. Enhancement of neutrophil-mediated injury to bovine pulmonary endothelial cells by Pasteurella haemolytica leukotoxin. 1993 Infect. Immun. pmid:8388866
Ohta H et al. Association of Actinobacillus actinomycetemcomitans leukotoxin with nucleic acids on the bacterial cell surface. 1993 Infect. Immun. pmid:8406888
Chang YF et al. Molecular characterization of a leukotoxin gene from a Pasteurella haemolytica-like organism, encoding a new member of the RTX toxin family. 1993 Infect. Immun. pmid:8478098
Zhang F et al. Functional replacement of the hemolysin A transport signal by a different primary sequence. 1993 Proc. Natl. Acad. Sci. U.S.A. pmid:8483936
Sato N et al. Effect of Ca2+ on the binding of Actinobacillus actinomycetemcomitans leukotoxin and the cytotoxicity to promyelocytic leukemia HL-60 cells. 1993 Biochem. Mol. Biol. Int. pmid:8508142
Ishizaki T et al. Endothelin-1 potentiates leukotoxin-induced edematous lung injury. 1995 J. Appl. Physiol. pmid:8567550
Flemmig TF et al. Identification of Actinobacillus actinomycetemcomitans in subgingival plaque by PCR. 1995 J. Clin. Microbiol. pmid:8586681
Iwase H et al. Monoepoxide production from linoleic acid by cytochrome c in the presence of cardiolipin. 1996 Biochem. Biophys. Res. Commun. pmid:8630079
Abouna GM et al. Comparison of the effect of plasmapheresis using human albumin or dextran 40 on the survival of pig-to-dog renal xenografts. 1996 Transplant. Proc. pmid:8644183
Stevens PK and Czuprynski CJ Pasteurella haemolytica leukotoxin induces bovine leukocytes to undergo morphologic changes consistent with apoptosis in vitro. 1996 Infect. Immun. pmid:8698496
Hritz M et al. Differential regulation of the leukotoxin operon in highly leukotoxic and minimally leukotoxic strains of Actinobacillus actinomycetemcomitans. 1996 Infect. Immun. pmid:8698501
Saginala S et al. Serum neutralizing antibody response and protection against experimentally induced liver abscesses in steers vaccinated with Fusobacterium necrophorum. 1996 Am. J. Vet. Res. pmid:8712511
Srinand S et al. Comparative evaluation of antibodies induced by commercial Pasteurella haemolytica vaccines using solid phase immunoassays. 1996 Vet. Microbiol. pmid:8734636
Haubek D et al. Highly toxic clone of Actinobacillus actinomycetemcomitans in geographically widespread cases of juvenile periodontitis in adolescents of African origin. 1996 J. Clin. Microbiol. pmid:8735124
Kolodrubetz D et al. cis Elements and trans factors are both important in strain-specific regulation of the leukotoxin gene in Actinobacillus actinomycetemcomitans. 1996 Infect. Immun. pmid:8751884
Ishizaki T et al. [Lung injury and pulmonary vascular endothelial cell injury]. 1995 Nihon Kyobu Shikkan Gakkai Zasshi pmid:8752510
Pellett S and Welch RA Escherichia coli hemolysin mutants with altered target cell specificity. 1996 Infect. Immun. pmid:8757837
Ludwig A Cytolytic toxins from gram-negative bacteria. 1996 Microbiologia pmid:8767711
Ishizaki T et al. Protective effects of BQ-123, an ETA receptor antagonist, against leukotoxin-induced injury in rat lungs. 1996 Am. J. Physiol. pmid:8843795
Rózalski A [Cytolysins and homologous proteins produced by gram-negative bacteria. I. Hemolysis and leukotoxins of Escherichia coli, Bordetella pertussis, Pasteurella haemolytica and Actinobacillus sp]. 1996 Postepy Hig Med Dosw pmid:8848425
Sreevatsan S et al. Evaluation of three experimental subunit vaccines against pneumonic pasteurellosis in cattle. 1996 Vaccine pmid:8852412
Bauer ME and Welch RA Association of RTX toxins with erythrocytes. 1996 Infect. Immun. pmid:8890223
Ramírez-Romero R and Brogden KA [Pathogenesis of lung damage caused by Pasteurella haemolytica]. 1995 Oct-Dec Rev. Latinoam. Microbiol. pmid:8900571
Sakai T et al. Role of nitric oxide and superoxide anion in leukotoxin-, 9,10-epoxy-12-octadecenoate-induced mitochondrial dysfunction. 1996 Free Radic. Biol. Med. pmid:8904303
DeBey BM et al. In vitro lymphocyte proliferative responses and gamma-interferon production as measures of cell-mediated immunity of cattle exposed to Pasteurella haemolytica. 1996 Can. J. Vet. Res. pmid:8904662

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