| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
Total
1
Maackiain
Maackiain is a lipid of Polyketides (PK) class. Maackiain is associated with abnormalities such as Allergic rhinitis NOS. The involved functions are known as Gene Expression, inhibitors, Drug Interactions, Transcriptional Activation and Phosphorylation. Maackiain often locates in Muscle, Structure of mucous membrane of nose, Cell Fraction and Protoplasm. The associated genes with Maackiain are IL4 gene and EMILIN1 gene.
Cross Reference
Introduction
To understand associated biological information of Maackiain, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Maackiain?
Maackiain is suspected in Allergic rhinitis NOS and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Maackiain
PubChem Associated disorders and diseases
What pathways are associated with Maackiain
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Maackiain?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Maackiain?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Maackiain?
There are no associated biomedical information in the current reference collection.
What genes are associated with Maackiain?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Maackiain?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Maackiain
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Li Y et al. | Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. | 2018 | Toxicol. Lett. | pmid:29753067 |
| Lee HW et al. | Potent selective monoamine oxidase B inhibition by maackiain, a pterocarpan from the roots of Sophora flavescens. | 2016 | Bioorg. Med. Chem. Lett. | pmid:27575476 |
| Fukui H et al. | [Molecular pharmacology of (-)maackiain, from Kujin, an anti-allergic Kampo medicine]. | 2016 | Nippon Yakurigaku Zasshi | pmid:26960774 |
| Gampe N et al. | Characterization and identification of isoflavonoid glycosides in the root of Spiny restharrow (Ononis spinosa L.) by HPLC-QTOF-MS, HPLC-MS/MS and NMR. | 2016 | J Pharm Biomed Anal | pmid:26874257 |
| Bezerra-Silva PC et al. | Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito. | 2015 | Exp. Parasitol. | pmid:25819294 |
| Jang SM et al. | Pharmacokinetic properties of trifolirhizin, (-)-maackiain, (-)-sophoranone and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran after intravenous and oral administration of Sophora tonkinensis extract in rats. | 2015 | Xenobiotica | pmid:26068519 |
| Nariai Y et al. | Disruption of Heat Shock Protein 90 (Hsp90)-Protein Kinase Cδ (PKCδ) Interaction by (-)-Maackiain Suppresses Histamine H1 Receptor Gene Transcription in HeLa Cells. | 2015 | J. Biol. Chem. | pmid:26391399 |
| Yin T et al. | Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping(Antitumor B). | 2015 | J Ethnopharmacol | pmid:26099633 |
| Yoo H et al. | Simultaneous determination of trifolirhizin, (-)-maackiain, (-)-sophoranone, and 2-(2,4-dihydroxyphenyl)-5,6-methylenedioxybenzofuran from Sophora tonkinensis in rat plasma by liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study. | 2014 | J Sep Sci | pmid:25156071 |
| Wu C et al. | [Simultaneous determination of 4 alkaloids and a flavonoid in Picrasmae Ramulus et Folium by RP-HPLC]. | 2014 | Zhongguo Zhong Yao Za Zhi | pmid:25095379 |