Glyceollin

Glyceollin is a lipid of Polyketides (PK) class. Glyceollin is associated with abnormalities such as Malignant Carcinoid Syndrome, Infection, infection induced, Diabetes and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Agent, Binding, Competitive, Signal Transduction, Gene Expression and Transcription, Genetic. Glyceollin often locates in Body tissue, Epithelium, viral nucleocapsid location, Membrane and Mouse Uterus. The associated genes with Glyceollin are CXCL12 wt Allele, PGR gene, Genes, Reporter, TFF1 gene and NGFR gene. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of Glyceollin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glyceollin?

Glyceollin is suspected in Malignant Carcinoid Syndrome, Infection, infection induced, Diabetes, Diabetes Mellitus, Non-Insulin-Dependent, hypercholesterolemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Glyceollin

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Glyceollin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glyceollin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Glyceollin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Glyceollin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Glyceollin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glyceollin?

Xenograft Model

Xenograft Model are used in the study 'Antiestrogenic glyceollins suppress human breast and ovarian carcinoma tumorigenesis.' (Salvo VA et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Glyceollin

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Authors Title Published Journal PubMed Link
Seo JY et al. Soybean-Derived Phytoalexins Improve Cognitive Function through Activation of Nrf2/HO-1 Signaling Pathway. 2018 Int J Mol Sci pmid:29337893
Drennen C et al. Cellular Pharmacokinetic Model-Based Analysis of Genistein, Glyceollin, and MK-571 Effects on 5 (and 6)-Carboxy-2',7'-Dichloroflourescein Disposition in Caco-2 Cells. 2018 J Pharm Sci pmid:29247742
Lecomte S et al. Glyceollins trigger anti-proliferative effects through estradiol-dependent and independent pathways in breast cancer cells. 2017 Cell Commun. Signal pmid:28666461
Seo H et al. Protective Effect of Glyceollins in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis. 2017 J Med Food pmid:28956670
Farrell K et al. Distinct Mechanisms of Biotic and Chemical Elicitors Enable Additive Elicitation of the Anticancer Phytoalexin Glyceollin I. 2017 Molecules pmid:28749423
van de Schans MG et al. Glyceollins and dehydroglyceollins isolated from soybean act as SERMs and ER subtype-selective phytoestrogens. 2016 J. Steroid Biochem. Mol. Biol. pmid:26655113
Yoneyama K et al. Molecular Characterization of Soybean Pterocarpan 2-Dimethylallyltransferase in Glyceollin Biosynthesis: Local Gene and Whole-Genome Duplications of Prenyltransferase Genes Led to the Structural Diversity of Soybean Prenylated Isoflavonoids. 2016 Plant Cell Physiol. pmid:27986914
Chimezie C et al. Glyceollin Effects on MRP2 and BCRP in Caco-2 Cells, and Implications for Metabolic and Transport Interactions. 2016 J Pharm Sci pmid:26296158
Schexnayder C and Stratford RE Genistein and Glyceollin Effects on ABCC2 (MRP2) and ABCG2 (BCRP) in Caco-2 Cells. 2015 Int J Environ Res Public Health pmid:26703673
Carriere PP et al. Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1. 2015 Int J Environ Res Public Health pmid:26703648