MeSH term | MeSH ID | Detail |
---|---|---|
Inflammation | D007249 | 119 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Glyceollin is a lipid of Polyketides (PK) class. Glyceollin is associated with abnormalities such as Malignant Carcinoid Syndrome, Infection, infection induced, Diabetes and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Agent, Binding, Competitive, Signal Transduction, Gene Expression and Transcription, Genetic. Glyceollin often locates in Body tissue, Epithelium, viral nucleocapsid location, Membrane and Mouse Uterus. The associated genes with Glyceollin are CXCL12 wt Allele, PGR gene, Genes, Reporter, TFF1 gene and NGFR gene. The related experimental models are Xenograft Model.
To understand associated biological information of Glyceollin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Glyceollin is suspected in Malignant Carcinoid Syndrome, Infection, infection induced, Diabetes, Diabetes Mellitus, Non-Insulin-Dependent, hypercholesterolemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Glyceollin
MeSH term | MeSH ID | Detail |
---|---|---|
Inflammation | D007249 | 119 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Antiestrogenic glyceollins suppress human breast and ovarian carcinoma tumorigenesis.' (Salvo VA et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Seo JY et al. | Soybean-Derived Phytoalexins Improve Cognitive Function through Activation of Nrf2/HO-1 Signaling Pathway. | 2018 | Int J Mol Sci | pmid:29337893 |
Drennen C et al. | Cellular Pharmacokinetic Model-Based Analysis of Genistein, Glyceollin, and MK-571 Effects on 5 (and 6)-Carboxy-2',7'-Dichloroflourescein Disposition in Caco-2 Cells. | 2018 | J Pharm Sci | pmid:29247742 |
Lecomte S et al. | Glyceollins trigger anti-proliferative effects through estradiol-dependent and independent pathways in breast cancer cells. | 2017 | Cell Commun. Signal | pmid:28666461 |
Seo H et al. | Protective Effect of Glyceollins in a Mouse Model of Dextran Sulfate Sodium-Induced Colitis. | 2017 | J Med Food | pmid:28956670 |
Farrell K et al. | Distinct Mechanisms of Biotic and Chemical Elicitors Enable Additive Elicitation of the Anticancer Phytoalexin Glyceollin I. | 2017 | Molecules | pmid:28749423 |
van de Schans MG et al. | Glyceollins and dehydroglyceollins isolated from soybean act as SERMs and ER subtype-selective phytoestrogens. | 2016 | J. Steroid Biochem. Mol. Biol. | pmid:26655113 |
Yoneyama K et al. | Molecular Characterization of Soybean Pterocarpan 2-Dimethylallyltransferase in Glyceollin Biosynthesis: Local Gene and Whole-Genome Duplications of Prenyltransferase Genes Led to the Structural Diversity of Soybean Prenylated Isoflavonoids. | 2016 | Plant Cell Physiol. | pmid:27986914 |
Chimezie C et al. | Glyceollin Effects on MRP2 and BCRP in Caco-2 Cells, and Implications for Metabolic and Transport Interactions. | 2016 | J Pharm Sci | pmid:26296158 |
Schexnayder C and Stratford RE | Genistein and Glyceollin Effects on ABCC2 (MRP2) and ABCG2 (BCRP) in Caco-2 Cells. | 2015 | Int J Environ Res Public Health | pmid:26703673 |
Carriere PP et al. | Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1. | 2015 | Int J Environ Res Public Health | pmid:26703648 |