| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Neoplasms | D011471 | 126 associated lipids |
Total
1
Psoralidin
Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.
Cross Reference
Introduction
To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Psoralidin?
Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Psoralidin
PubChem Associated disorders and diseases
What pathways are associated with Psoralidin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Psoralidin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Psoralidin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Psoralidin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Psoralidin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Psoralidin?
Xenograft Model
Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Psoralidin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alalaiwe A et al. | The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions: The relationship between structure and percutaneous absorption. | 2018 | Eur J Pharm Sci | pmid:30153523 |
| Zhai Y et al. | The higher osteoprotective activity of psoralidin in vivo than coumestrol is attributed by its presence of an isopentenyl group and through activated PI3K/Akt axis. | 2018 | Biomed. Pharmacother. | pmid:29710518 |
| Rao Z et al. | Protective effects of psoralidin on IL‑1β‑induced chondrocyte apoptosis. | 2018 | Mol Med Rep | pmid:29257269 |
| Kong L et al. | Psoralidin suppresses osteoclastogenesis in BMMs and attenuates LPS-mediated osteolysis by inhibiting inflammatory cytokines. | 2017 | Int. Immunopharmacol. | pmid:28779592 |
| Chen CH et al. | Isoflavones and anti-inflammatory constituents from the fruits of Psoralea corylifolia. | 2017 | Phytochemistry | pmid:28825980 |
| Pal D et al. | Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis. | 2017 | Br. J. Cancer | pmid:28588318 |
| Zhai Y et al. | Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance bone formation of osteoblasts and decrease bone resorption of osteoclasts. | 2017 | Eur. J. Pharmacol. | pmid:28283388 |
| Pal D et al. | Targeting aberrant expression of Notch-1 in ALDH cancer stem cells in breast cancer. | 2017 | Mol. Carcinog. | pmid:27753148 |
| Shi X et al. | Comparison of the in vitro metabolism of psoralidin among different species and characterization of its inhibitory effect against UDP- glucuronosyltransferase (UGT) or cytochrome p450 (CYP450) enzymes. | 2016 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:27428458 |
| Ren G et al. | Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells. | 2016 | Phytomedicine | pmid:27387402 |
| Yin J et al. | Nanoencapsulation of psoralidin via chitosan and Eudragit S100 for enhancement of oral bioavailability. | 2016 | Int J Pharm | pmid:27154253 |
| Sun H et al. | Regio- and isoform-specific glucuronidation of psoralidin: evaluation of 3-o-glucuronidation as a functional marker for UGT1A9. | 2015 | J Pharm Sci | pmid:25941108 |
| Zhang XS et al. | Herb-drug interaction between irinotecan and psoralidin-containing herbs. | 2015 | Eur J Drug Metab Pharmacokinet | pmid:25216634 |
| Song K et al. | In vitro and in vivo assessment of the effect of antiprotozoal compounds isolated from Psoralea corylifolia against Ichthyophthirius multifiliis in fish. | 2015 | Int J Parasitol Drugs Drug Resist | pmid:26042195 |
| Das TP et al. | Induction of reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells. | 2014 | Mol. Carcinog. | pmid:23475579 |
| Liu X et al. | Psoralidin, a coumestan analogue, as a novel potent estrogen receptor signaling molecule isolated from Psoralea corylifolia. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24507928 |
| Li JP et al. | [Study on effect of psoralidin on anti-experimental postmenopausal osteoporosis and its mechanism]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:24010302 |
| Suman S et al. | Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. | 2013 | Br. J. Cancer | pmid:24129237 |
| Bronikowska J et al. | The coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). | 2012 | Molecules | pmid:22643355 |
| Yang HJ et al. | Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation. | 2011 | Biochem. Pharmacol. | pmid:21669192 |
| Chiou WF et al. | Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. | 2011 | Eur. J. Pharmacol. | pmid:20951127 |
| Qiu RL et al. | [Study on the chemical constituents of Psoralea corylifolia]. | 2011 | Zhong Yao Cai | pmid:22233033 |
| Wang Y et al. | Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds. | 2011 | Evid Based Complement Alternat Med | pmid:19131395 |
| Retraction. Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells. | 2011 | Cancer Prev Res (Phila) | pmid:22025547 | |
| Szliszka E et al. | Enhanced TRAIL-mediated apoptosis in prostate cancer cells by the bioactive compounds neobavaisoflavone and psoralidin isolated from Psoralea corylifolia. | 2011 | Pharmacol Rep | pmid:21441621 |
| Kumar R et al. | Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer. | 2010 | Mol. Cancer Ther. | pmid:20736346 |
| Srinivasan S et al. | Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer. | 2010 | Apoptosis | pmid:19851870 |
| Xiao G et al. | Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. | 2010 | J Chromatogr A | pmid:20663508 |
| Khushboo PS et al. | Psoralea corylifolia Linn.-"Kushtanashini". | 2010 | Pharmacogn Rev | pmid:22228944 |
| Pahari P and Rohr J | Total synthesis of psoralidin, an anticancer natural product. | 2009 | J. Org. Chem. | pmid:19254011 |
| Kumar R et al. | Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells. | 2009 | Cancer Prev Res (Phila) | pmid:19223576 |
| Lee SJ et al. | Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells. | 2009 | Arch. Pharm. Res. | pmid:19641888 |
| Koduru S et al. | Identification of a potent herbal molecule for the treatment of breast cancer. | 2009 | BMC Cancer | pmid:19183448 |
| Yi LT et al. | Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice. | 2008 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:18006202 |
| Chen Y et al. | Transcriptional regulation of corticotrophin releasing factor gene by furocoumarins isolated from seeds of Psoralea corylifolia. | 2008 | Life Sci. | pmid:18445497 |
| Qiao CF et al. | Chemical fingerprint and quantitative analysis of fructus psoraleae by high-performance liquid chromatography. | 2007 | J Sep Sci | pmid:17536725 |
| Matsuda H et al. | Bioactive constituents from Chinese natural medicines. XX. Inhibitors of antigen-induced degranulation in RBL-2H3 cells from the seeds of Psoralea corylifolia. | 2007 | Chem. Pharm. Bull. | pmid:17202711 |
| Zhao L et al. | Fingerprint analysis of Psoralea corylifolia L. by HPLC and LC-MS. | 2005 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15905140 |
| Kim YC et al. | In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia. | 2005 | Planta Med. | pmid:15678382 |
| Mar W et al. | Cytotoxic constituents of Psoralea corylifolia. | 2001 | Arch. Pharm. Res. | pmid:11440079 |
| Yang YM et al. | The cytotoxicity of psoralidin from Psoralea corylifolia. | 1996 | Planta Med. | pmid:8792669 |
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