Psoralidin

Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Psoralidin?

Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Psoralidin

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Psoralidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Psoralidin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Psoralidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Psoralidin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Psoralidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Psoralidin?

Xenograft Model

Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Psoralidin

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Authors Title Published Journal PubMed Link
pmid:
Srinivasan S et al. Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer. 2010 Apoptosis pmid:19851870
Mar W et al. Cytotoxic constituents of Psoralea corylifolia. 2001 Arch. Pharm. Res. pmid:11440079
Lee SJ et al. Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells. 2009 Arch. Pharm. Res. pmid:19641888
Yang HJ et al. Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation. 2011 Biochem. Pharmacol. pmid:21669192
Zhai Y et al. The higher osteoprotective activity of psoralidin in vivo than coumestrol is attributed by its presence of an isopentenyl group and through activated PI3K/Akt axis. 2018 Biomed. Pharmacother. pmid:29710518
Liu X et al. Psoralidin, a coumestan analogue, as a novel potent estrogen receptor signaling molecule isolated from Psoralea corylifolia. 2014 Bioorg. Med. Chem. Lett. pmid:24507928
Koduru S et al. Identification of a potent herbal molecule for the treatment of breast cancer. 2009 BMC Cancer pmid:19183448
Suman S et al. Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. 2013 Br. J. Cancer pmid:24129237
Pal D et al. Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis. 2017 Br. J. Cancer pmid:28588318