MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.
To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Psoralidin
MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Srinivasan S et al. | Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer. | 2010 | Apoptosis | pmid:19851870 |
Mar W et al. | Cytotoxic constituents of Psoralea corylifolia. | 2001 | Arch. Pharm. Res. | pmid:11440079 |
Lee SJ et al. | Induction of quinone reductase activity by psoralidin isolated from Psoralea corylifolia in mouse hepa 1c1c7 cells. | 2009 | Arch. Pharm. Res. | pmid:19641888 |
Yang HJ et al. | Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation. | 2011 | Biochem. Pharmacol. | pmid:21669192 |
Zhai Y et al. | The higher osteoprotective activity of psoralidin in vivo than coumestrol is attributed by its presence of an isopentenyl group and through activated PI3K/Akt axis. | 2018 | Biomed. Pharmacother. | pmid:29710518 |
Liu X et al. | Psoralidin, a coumestan analogue, as a novel potent estrogen receptor signaling molecule isolated from Psoralea corylifolia. | 2014 | Bioorg. Med. Chem. Lett. | pmid:24507928 |
Koduru S et al. | Identification of a potent herbal molecule for the treatment of breast cancer. | 2009 | BMC Cancer | pmid:19183448 |
Suman S et al. | Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. | 2013 | Br. J. Cancer | pmid:24129237 |
Pal D et al. | Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis. | 2017 | Br. J. Cancer | pmid:28588318 |