MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.
To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Psoralidin
MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Yang YM et al. | The cytotoxicity of psoralidin from Psoralea corylifolia. | 1996 | Planta Med. | pmid:8792669 |
Mar W et al. | Cytotoxic constituents of Psoralea corylifolia. | 2001 | Arch. Pharm. Res. | pmid:11440079 |
Zhao L et al. | Fingerprint analysis of Psoralea corylifolia L. by HPLC and LC-MS. | 2005 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:15905140 |
Kim YC et al. | In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia. | 2005 | Planta Med. | pmid:15678382 |
Qiao CF et al. | Chemical fingerprint and quantitative analysis of fructus psoraleae by high-performance liquid chromatography. | 2007 | J Sep Sci | pmid:17536725 |
Matsuda H et al. | Bioactive constituents from Chinese natural medicines. XX. Inhibitors of antigen-induced degranulation in RBL-2H3 cells from the seeds of Psoralea corylifolia. | 2007 | Chem. Pharm. Bull. | pmid:17202711 |
Yi LT et al. | Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice. | 2008 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:18006202 |
Chen Y et al. | Transcriptional regulation of corticotrophin releasing factor gene by furocoumarins isolated from seeds of Psoralea corylifolia. | 2008 | Life Sci. | pmid:18445497 |
Pahari P and Rohr J | Total synthesis of psoralidin, an anticancer natural product. | 2009 | J. Org. Chem. | pmid:19254011 |